The hope and hype of ellagic acid and urolithins as ligands of SARS-CoV-2 Nsp5 and inhibitors of viral replication.

Autor: Bianconi E; Department of Pharmaceutical Sciences, University of Perugia, Perugia, Italy., Gidari A; Department of Medicine and Surgery, Clinic of Infectious Diseases, University of Perugia, Perugia, Italy., Souma M; Department of Pharmaceutical Sciences, University of Perugia, Perugia, Italy., Sabbatini S; Medical Microbiology Section, Department of Medicine and Surgery, University of Perugia, Perugia, Italy., Grifagni D; Centre for Magnetic Resonance, University of Florence, Sesto Fiorentino, Italy.; Department of Chemistry, University of Florence, Sesto Fiorentino, Italy., Bigiotti C; Department of Pharmaceutical Sciences, University of Perugia, Perugia, Italy., Schiaroli E; Department of Medicine and Surgery, Clinic of Infectious Diseases, University of Perugia, Perugia, Italy., Comez L; Istituto Officina dei Materiali-IOM, National Research Council-CNR, Perugia, Italy., Paciaroni A; Department of Physics and Geology, University of Perugia, Perugia, Italy., Cantini F; Centre for Magnetic Resonance, University of Florence, Sesto Fiorentino, Italy.; Department of Chemistry, University of Florence, Sesto Fiorentino, Italy., Francisci D; Department of Medicine and Surgery, Clinic of Infectious Diseases, University of Perugia, Perugia, Italy., Macchiarulo A; Department of Pharmaceutical Sciences, University of Perugia, Perugia, Italy.

Publikováno v: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2023 Dec; Vol. 38 (1), pp. 2251721.

The effect of male fetal gender on the cesarean section rate in Greek women with induced labor.

Autor: Antonakou, A.¹ angelantonakou@gmail.com, Souma, M.¹, Tsourlou, E.¹, Papoutsis, D.²

Publikováno v: Archives of Hellenic Medicine / Arheia Ellenikes Iatrikes. 2019, Vol. 36 Issue 5, p643-649. 7p.

Development of 3α,7α-dihydroxy-6α-ethyl-24-nor-5β-cholan-23-sulfate sodium salt (INT-767): Process optimization, synthesis and characterization of metabolites.

Autor: Cerra B; Laboratory of Medicinal and Advanced Synthetic Chemistry, Department of Pharmaceutical Sciences, University of Perugia, Via del Liceo 1, 06122, Perugia, Italy., Venturoni F; Laboratory of Medicinal and Advanced Synthetic Chemistry, Department of Pharmaceutical Sciences, University of Perugia, Via del Liceo 1, 06122, Perugia, Italy., Souma M; Laboratory of Medicinal and Advanced Synthetic Chemistry, Department of Pharmaceutical Sciences, University of Perugia, Via del Liceo 1, 06122, Perugia, Italy., Ceccarelli G; Laboratory of Medicinal and Advanced Synthetic Chemistry, Department of Pharmaceutical Sciences, University of Perugia, Via del Liceo 1, 06122, Perugia, Italy., Lozza AM; Laboratory of Medicinal and Advanced Synthetic Chemistry, Department of Pharmaceutical Sciences, University of Perugia, Via del Liceo 1, 06122, Perugia, Italy., Passeri D; TES Pharma, Via Palmiro Togliatti 20, 06073, Taverne di Corciano, Perugia, Italy., De Franco F; TES Pharma, Via Palmiro Togliatti 20, 06073, Taverne di Corciano, Perugia, Italy., Baxendale IR; Department of Chemistry, Durham University, South Road, Durham, United Kingdom., Pellicciari R; TES Pharma, Via Palmiro Togliatti 20, 06073, Taverne di Corciano, Perugia, Italy., Macchiarulo A; Laboratory of Medicinal and Advanced Synthetic Chemistry, Department of Pharmaceutical Sciences, University of Perugia, Via del Liceo 1, 06122, Perugia, Italy., Gioiello A; Laboratory of Medicinal and Advanced Synthetic Chemistry, Department of Pharmaceutical Sciences, University of Perugia, Via del Liceo 1, 06122, Perugia, Italy. Electronic address: antimo.gioiello@unipg.it.

Publikováno v: European journal of medicinal chemistry [Eur J Med Chem] 2022 Nov 15; Vol. 242, pp. 114652. Date of Electronic Publication: 2022 Aug 20.

Critical Assessment of a Structure-Based Screening Campaign for IDO1 Inhibitors: Tips and Pitfalls.

Autor: Mammoli A; Department of Pharmaceutical Sciences, University of Perugia, Via del Liceo n.1, 06123 Perugia, Italy., Bianconi E; Department of Pharmaceutical Sciences, University of Perugia, Via del Liceo n.1, 06123 Perugia, Italy., Ruta L; Department of Pharmaceutical Sciences, University of Perugia, Via del Liceo n.1, 06123 Perugia, Italy., Riccio A; Department of Pharmaceutical Sciences, University of Perugia, Via del Liceo n.1, 06123 Perugia, Italy., Bigiotti C; Department of Pharmaceutical Sciences, University of Perugia, Via del Liceo n.1, 06123 Perugia, Italy., Souma M; Department of Pharmaceutical Sciences, University of Perugia, Via del Liceo n.1, 06123 Perugia, Italy., Carotti A; Department of Pharmaceutical Sciences, University of Perugia, Via del Liceo n.1, 06123 Perugia, Italy., Rossini S; Department of Medicine and Surgery, University of Perugia, P.le Gambuli, 06132 Perugia, Italy., Suvieri C; Department of Medicine and Surgery, University of Perugia, P.le Gambuli, 06132 Perugia, Italy., Pallotta MT; Department of Medicine and Surgery, University of Perugia, P.le Gambuli, 06132 Perugia, Italy., Grohmann U; Department of Medicine and Surgery, University of Perugia, P.le Gambuli, 06132 Perugia, Italy., Camaioni E; Department of Pharmaceutical Sciences, University of Perugia, Via del Liceo n.1, 06123 Perugia, Italy., Macchiarulo A; Department of Pharmaceutical Sciences, University of Perugia, Via del Liceo n.1, 06123 Perugia, Italy.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2022 Apr 02; Vol. 23 (7). Date of Electronic Publication: 2022 Apr 02.

Ellagic acid alleviates NLRP6/caspase-1/GSDMD-mediated inflammation and pyroptosis in rats post cerebral ischemia/ reperfusion injury.

Autor: Ling Hu¹, Xiaoqiong Wei², Guofu Shen², Xiaohuan Huang¹ huangxiaohuan@cqtgmc.edu.cn

Publikováno v: Iranian Journal of Basic Medical Sciences. Jan2025, Vol. 28 Issue 1, p105-112. 8p.