Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Soula Ganiatsas"'
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Akademický článek
A randomised phase II trial to examine feasibility of standardised, early palliative (STEP) care for patients with advanced cancer and their families [ACTRN12617000534381]: a research protocol
Autor: Jennifer Philip, Anna Collins, Brian Le, Vijaya Sundararajan, Caroline Brand, Susan Hanson, Jon Emery, Peter Hudson, Linda Mileshkin, Soula Ganiatsas
Publikováno v: Pilot and Feasibility Studies, Vol 5, Iss 1, Pp 1-10 (2019)
Abstract Background Current international consensus is that ‘early’ referral to palliative care services improves cancer patient and family carer outcomes; however, in practice, these referrals are not routine. Uncertainty about the ‘best time
Externí odkaz: https://doaj.org/article/5d4dfe4af9974be5bf0e91e7e07525fd
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2
E2F4 Is Essential for Normal Erythrocyte Maturation and Neonatal Viability
Autor: Susan E. Erdman, Catherine Rogers, Rebecca L. Landsberg, Patrick O. Humbert, Carlo Brugnara, Roderick T. Bronson, Jeffrey M. Trimarchi, Jacqueline A. Lees, Soula Ganiatsas, Mark D. Schrenzel, Savita Dandapani
Publikováno v: Molecular Cell. 6(2):281-291
The retinoblastoma protein (pRB) plays a key role in the control of normal development and proliferation through the regulation of the E2F transcription factors. We generated a mutant mouse model to assess the in vivo role of the predominant E2F fami
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c91cd72801a953045ed4db5713e1580
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3
SEK1/MKK4 Is Required for Maintenance of a Normal Peripheral Lymphoid Compartment but Not for Lymphocyte Development
Autor: Roger Ferrini, Mark A. Labow, Ramnik J. Xavier, Frederick W. Alt, Soula Ganiatsas, Wojciech Swat, Richard A. Flavell, Roger J. Davis, Nancy L. Harris, Leonard I. Zon, Di Yang, Keiko Fujikawa, Laurie Davidson
Publikováno v: Immunity. 8(5):625-634
SAPK is a member of the group of evolutionary conserved stress-activated kinases that mediate control of cellular death and proliferation. In lymphocytes, the SAPK pathway has been implicated in signaling from antigen, costimulatory, and death recept
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5936a4074dec5853338179b149ee42aa
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4
Alternative mammary oncogenic pathways are induced by D-type cyclins; MMTV-cyclin D3 transgenic mice develop squamous cell carcinoma
Autor: Paul Waring, Joy Hendley, Anne Thompson, Doris Germain, Kerry Warren, Renee Dow, Andreja Pirkmaier, Soula Ganiatsas
Publikováno v: Oncogene. 22(28)
The three human D-type cyclins, cyclin D1, D2 and D3 share the ability to bind to and activate cdk4 and 6. MMTV-cyclin D1 transgenic mice develop mainly adenocarcinoma, while MMTV-cyclin D2 mice show a lack of alveologenesis during pregnancy and only
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47c4c7d97809b4dc6dfc251c8c88cfcd
https://pubmed.ncbi.nlm.nih.gov/12853979
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5
Role of MEKK2-MEK5 in the regulation of TNF-α gene expression and MEKK2-MKK7 in the activation of c-Jun N-terminal kinase in mast cells
Autor: Soula Ganiatsas, Timothy P. Garrington, Philip J. Papst, Tamotsu Ishizuka, Gary L. Johnson, Kosuke Chayama, Saiphone Webb, Erwin W. Gelfand, Joanne C. Pratt, Leonard I. Zon, Weiyong Sun
Cross-linking of the high-affinity IgE receptor (FcepsilonRI) on mast cells with IgE and multivalent antigen triggers mitogen-activated protein (MAP) kinase activation and cytokine gene expression. We report here that MAP kinase kinase 4 (MKK4) gene
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::debe2f61be3667e139812f52c792e21c
https://europepmc.org/articles/PMC31880/
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6
A splice variant of Skp2 is retained in the cytoplasm and fails to direct cyclin D1 ubiquitination in the uterine cancer cell line SK-UT
Autor: Soula Ganiatsas, Anne Thompson, Brenda A. Schulman, Renee Dow, Doris Germain
Publikováno v: Oncogene. 20(28)
Cyclin D1 is an important regulator of the transition from G1 into S phase of the cell cycle. The level to which cyclin D1 accumulates is tightly regulated. One mechanism contributing to the control of cyclin D1 levels is the regulation of its ubiqui
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87077c1a42e90ed5dd12a7b17a1506e7
https://pubmed.ncbi.nlm.nih.gov/11439327
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7
In vivo immunological function of mast cells derived from embryonic stem cells: An approach for the rapid analysis of even embryonic lethal mutations in adult mice in vivo
Autor: Jochen Wedemeyer, Mindy Tsai, Leonard I. Zon, Stephen J. Galli, Soula Ganiatsas, See-Ying Tam
An important goal of tissue engineering is to achieve reconstitution of specific functionally active cell types by transplantation of differentiated cell populations derived from normal or genetically altered embryonic stem cellsin vitro. We find tha
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c56477ab3c274bb1152709402f7949cb
https://europepmc.org/articles/PMC16843/
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8
SEK1 deficiency reveals mitogen-activated protein kinase cascade crossregulation and leads to abnormal hepatogenesis
Autor: Leonard I. Zon, Yuko Fujiwara, Tohru Ikeda, Lia Kwee, Andrew C. Perkins, Soula Ganiatsas, Mark A. Labow
SEK1 (MKK4/JNKK) is a mitogen-activated protein kinase activator that has been shown to participate in vitro in two stress-activated cascades terminating with the SAPK and p38 kinases. To define the role of SEK1 in vivo , we studied stress-induced si
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff1ab0c70fe305b4605c9511c7c20e64
https://europepmc.org/articles/PMC22670/
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