Výsledky vyhledávání - "Soujanya Ratna Edupuganti"

Antigenic burden and serum IgG concentrations influence rituximab pharmacokinetics in rheumatoid arthritis patients

Autor: Theodora Bejan-Angoulvant, Gilles Thibault, David Ternant, Julien Mélet, Gilles Paintaud, Christophe Passot, Bertrand Lioger, Valérie Gouilleux-Gruart, Denis Mulleman, Soujanya Ratna Edupuganti, Céline Desvignes

Publikováno v: British Journal of Clinical Pharmacology. 83:1773-1781

Aims Rituximab is a monoclonal antibody directed against CD20, which is approved in rheumatoid arthritis (RA). This study aimed at assessing the influence of CD19+ cell counts as target-antigen amount, and of immunoglobulin G (IgG) serum concentratio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::968f40edf199c94b7eed9ef8dfc64be6
https://doi.org/10.1111/bcp.13270

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Generation of anti-zearalenone scFv and its incorporation into surface plasmon resonance-based assay for the detection of zearalenone in sorghum

Autor: Soujanya Ratna Edupuganti, Richard O'Kennedy, Om Prakash Edupuganti

Publikováno v: Food Control. 34:668-674

Recombinant scFvs to zearalenone were isolated by phage display, expressed in Escherichia coli and the analytical sensitivity of selected scFvs determined by competitive inhibition enzyme-linked immunoassay (CI-ELISA) and surface plasmon resonance (S

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::792abe68134b2b90b6a7a5cc4b745d62
https://doi.org/10.1016/j.foodcont.2013.06.013

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Biological and synthetic binders for immunoassay and sensor-based detection: generation and characterisation of an anti-AFB2 single-chain variable fragment (scFv)

Autor: Richard O'Kennedy, Om Prakash Edupuganti, Soujanya Ratna Edupuganti

Publikováno v: World Mycotoxin Journal. 6:273-280

Aflatoxins are highly carcinogenic in nature and occur in a variety of food and feed samples. To ensure food is free from aflatoxins and safe for human consumption, methods to detect these toxins are necessary. Both aflatoxin B1 and aflatoxin B2 (AFB

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c573216f01e9ef7d4d7e1a13e00c145a
https://doi.org/10.3920/wmj2012.1523

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Development and validation of an enzyme-linked immunosorbent assay to measure adalimumab concentration

Autor: Anne-Claire Duveau, Céline Desvignes, Gilles Paintaud, Soujanya Ratna Edupuganti, François Darrouzain, Denis Mulleman, Amy Loercher

Publikováno v: Bioanalysis
Bioanalysis, Future Science, 2015, 7 (10), pp.1253-1260. ⟨10.4155/bio.15.30⟩

Background: Adalimumab is a therapeutic antibody used for treating inflammatory diseases. To understand interindividual PK variability, there is a need to develop and validate an assay to measure serum adalimumab concentrations. Methods: An ELISA was

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03484ec47ab87cae15949a19756db83e
https://hal.archives-ouvertes.fr/hal-02372930

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F-18 fluorodeoxyglucose positron emission tomography can detect early response to adalimumab, a tumor necrosis factor-α antagonist, in rheumatoid arthritis: A prospective pilot study

Autor: Soujanya Ratna Edupuganti, Philippe Goupille, David Ternant, Denis Mulleman, Gilles Paintaud, François Tranquart, Maxime Courtehoux, Véronique Eder

Publikováno v: Joint bone spine. 82(5)

Joint Bone Spine - In Press.Proof corrected by the author Available online since samedi 14 mars 2015

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08005f408100e5a2340eca272a77f436
https://pubmed.ncbi.nlm.nih.gov/25776440

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Use of T-2 toxin-immobilized amine-activated beads as an efficient affinity purification matrix for the isolation of specific IgY

Autor: Stéphanie Boullanger, Om Prakash Edupuganti, Richard O'Kennedy, Eric Defrancq, Soujanya Ratna Edupuganti

Publikováno v: Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences
Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences, Elsevier, 2013, pp.98-101
Europe PubMed Central

An affinity purification method that isolates T-2 toxin-specific IgY utilizing a T-2-toxin-immobilized column was developed. The T-2 toxin was covalently coupled via a carbonyldiimidazole-activated hydroxyl functional group to amine-activated sepharo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c063dd5e7ce92dde328c36445220a64c
https://hal.archives-ouvertes.fr/hal-00825418

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A highly stable, sensitive, regenerable and rapid immunoassay for detecting aflatoxin B1 in corn incorporating covalent AFB1 immobilization and a recombinant Fab antibody

Autor: Stephen Hearty, Om Prakash Edupuganti, Richard O'Kennedy, Soujanya Ratna Edupuganti

Publikováno v: Talanta. 115

A highly robust immunoassay applicable for the detection of aflatoxin B1 (AFB1) using a Fab antibody fragment was developed. A key factor was the use of covalently immobilized AFB1 which allowed an almost three fold increase in sensitivity, reduced a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bece5a1799ba48455ee3546ffbf93179
https://pubmed.ncbi.nlm.nih.gov/24054599

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