Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Souichi Oomizu"'
Autor:
Souichi Oomizu, Tomohiro Arikawa, Toshiro Niki, Takeshi Kadowaki, Masaki Ueno, Nozomu Nishi, Akira Yamauchi, Toshio Hattori, Tsutomu Masaki, Mitsuomi Hirashima
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e48574 (2012)
Galectin-9 (Gal-9), a β-galactoside binding mammalian lectin, regulates immune responses by reducing pro-inflammatory IL-17-producing Th cells (Th17) and increasing anti-inflammatory Foxp3(+) regulatory T cells (Treg) in vitro and in vivo. These fun
Externí odkaz:
https://doaj.org/article/beed98f5aced4d01a089f68cb14b92e5
Autor:
Shinsuke Tsumura, Tomohiro Arikawa, Keisuke Kojima, Mitsuomi Hirashima, Reina Tanaka, Naoki Saita, Souichi Oomizu, Aiko Masunaga, Toshiro Niki, Hirotsugu Kohrogi, Eisuke Goto
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 184:328-339
Galectin (Gal)-9 plays a crucial role in the modulation of innate and adaptive immunity.To investigate whether Gal-9 plays a role in a murine acute lung injury (ALI) model.C57BL/6 mice were pretreated with Gal-9 by subcutaneous injection 24 and 48 ho
Autor:
Naoki Saita, Masako Seki, Megumi Nagayama, Tomohiro Arikawa, Rika Shinonaga, Ken Mei Sakata, Keisuke Takeshita, Akihiro Matsukawa, Souichi Oomizu, Kanako Ito, Toshiro Niki, Kota Watanabe, Mitsuomi Hirashima
Publikováno v:
Bone. 44:849-857
Galectin-9 (Gal-9), a beta-galactoside binding lectin, plays a crucial role in innate and adaptive immunity. In the rat collagen-induced arthritis model, administration of Gal-9 induced repair of existing cartilage injury even when joints were alread
Autor:
Akira Yamauchi, Toshiro Niki, Tomohiro Arikawa, Minoru Miyake, Keiko Nagahara, Souichi Oomizu, Mitsuomi Hirashima, Keisuke Takeshita, Shigeki Katoh, Nozomu Nishi, Atsuya Nobumoto
Publikováno v:
Clinical Immunology. 130:322-330
Galectin-9 (Gal-9) inhibits the metastasis of tumor cells by blocking their adhesion to endothelium and the extracellular matrix. In this study, we addressed the involvement of Gal-9 in anti-tumor activity. Gal-9 significantly prolonged the survival
Autor:
Akira Yamauchi, Keisuke Takeshita, Akira Tominaga, Shigeki Katoh, Toshiro Niki, Souichi Oomizu, Atsuya Nobumoto, Keiko Nagahara, Nozomu Nishi, Mitsuomi Hirashima
Publikováno v:
Glycobiology. 18:735-744
We previously described an inverse correlation between galectin-9 (Gal-9) expression and metastasis in patients with malignant melanoma and breast cancer. This study verified the ability of Gal-9 to inhibit lung metastasis in experimental mouse model
Autor:
Kota Watanabe, Mitsuomi Hirashima, Kanako Ito, Tomohiro Arikawa, Akihiro Matsukawa, Akira Yamauchi, Ken Mei Sakata, Souichi Oomizu, Keisuke Takeshita, Masako Seki, Toshiro Niki, Atsuko Sakata, Shigeki Katoh, Vijay K. Kuchroo, Nozomu Nishi, Naoki Saita
Publikováno v:
Clinical Immunology. 127:78-88
The effects of galectin-9 on a mouse collagen-induced arthritis (CIA) model were assessed to clarify whether galectin-9 suppresses CIA by regulating T cell immune responses. Galectin-9 suppressed CIA in a dose-dependent manner, and such suppression w
Autor:
Souichi Oomizu, Mitsuomi Hirashima, Shulan Zhang, Akira Yamauchi, Tomohiro Arikawa, Meiyan Liang, Masaki Ueno, Rika Shinonaga
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 134:899-907
Galectin-9 (Gal-9) induces adhesion and aggregation of certain cell types and can be a prognostic factor in the patients with melanoma and breast cancer. We assessed the experiments to resolve whether Gal-9 expression in cervical neoplasm links to ma
Autor:
Akira Yamauchi, Shu-Yan Dai, Mitsuomi Hirashima, Atsuko Sakata, Toshiro Niki, Kanako Ito, Kenmei Sakata, Vijay K. Kuchroo, Atsuya Nobumoto, Michishi Tsukano, Masaki Ueno, Tomohiro Arikawa, Masako Seki, Nozomu Nishi, Souichi Oomizu, Shigeki Katoh, Kouichiro Ishikawa, Naoki Saita
Publikováno v:
Arthritis & Rheumatism. 56:3968-3976
Objective. To compare the expression of galectin 9 (Gal-9) in synovial tissue (ST) from rheumatoid arthritis (RA) patients and osteoarthritis (OA) patients and to evaluate the effects of Gal-9 on fibroblast-like synoviocytes (FLS) in these patients.
Fucoidan prevents Cε germline transcription and NFκB p52 translocation for IgE production in B cells
Publikováno v:
Biochemical and Biophysical Research Communications. 350:501-507
Fucoidan, a dietary fiber contained in seaweed, reduces the increase of antigen-specific IgE in mice exposed to ovalbumin. In this study, we investigated the effect of fucoidan on IgE production and intracellular events in B cells in vitro. Fucoidan
Publikováno v:
Endocrinology. 146:4179-4188
The neurotransmitter dopamine is known to inhibit prolactin secretion and the proliferation of lactotropes in the pituitary gland. In this study, we determined whether dopamine and TGFbeta1 interact to regulate lactotropic cell proliferation. We foun