Comparative small molecule screening of primary human acute leukemias, engineered human leukemia and leukemia cell lines.

Autor: Safa-Tahar-Henni S; Laboratory for High Throughput Biology, Montréal, QC, Canada.; Institute for Research in Immunology and Cancer, Montréal, QC, Canada., Páez Martinez K; Laboratory for High Throughput Biology, Montréal, QC, Canada.; Institute for Research in Immunology and Cancer, Montréal, QC, Canada., Gress V; Unité de recherche en immuno-hémato-oncologie Charles-Bruneau, Centre de recherche Azrieli du CHU Sainte-Justine, Montréal, QC, Canada., Esparza N; Centre de recherche en infectiologie du CHUL, Centre de recherche du CHU de Québec - Université Laval, Québec City, QC, Canada., Roques É; Laboratory for High Throughput Biology, Montréal, QC, Canada.; Institute for Research in Immunology and Cancer, Montréal, QC, Canada., Bonnet-Magnaval F; Laboratory for High Throughput Biology, Montréal, QC, Canada.; Institute for Research in Immunology and Cancer, Montréal, QC, Canada., Bilodeau M; Unité de recherche en immuno-hémato-oncologie Charles-Bruneau, Centre de recherche Azrieli du CHU Sainte-Justine, Montréal, QC, Canada., Gagné V; Laboratory for High Throughput Biology, Montréal, QC, Canada.; Institute for Research in Immunology and Cancer, Montréal, QC, Canada., Bresson E; Centre de recherche en infectiologie du CHUL, Centre de recherche du CHU de Québec - Université Laval, Québec City, QC, Canada., Cardin S; Unité de recherche en immuno-hémato-oncologie Charles-Bruneau, Centre de recherche Azrieli du CHU Sainte-Justine, Montréal, QC, Canada., El-Hachem N; Unité de recherche en immuno-hémato-oncologie Charles-Bruneau, Centre de recherche Azrieli du CHU Sainte-Justine, Montréal, QC, Canada., Iasenza I; Centre for Translational Biology, McGill University Heath Centre Research Institute, Montréal, QC, Canada., Alzial G; Institute for Research in Immunology and Cancer, Montréal, QC, Canada.; Metabolic and Epigenetic Alterations in Cancer Research unit, Montréal, QC, Canada., Boivin I; Institute for Research in Immunology and Cancer, Montréal, QC, Canada.; Molecular Genetics of Stem Cells Research Unit, Montréal, QC, Canada., Nakamichi N; Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, BC, Canada., Soufflet AC; Unité de recherche en immuno-hémato-oncologie Charles-Bruneau, Centre de recherche Azrieli du CHU Sainte-Justine, Montréal, QC, Canada., Mirela Pascariu C; Institute for Research in Immunology and Cancer, Montréal, QC, Canada.; Proteomics and Bioanalytical Mass Spectrometry Research Unit, Montréal, QC, Canada., Duchaine J; Institute for Research in Immunology and Cancer, Montréal, QC, Canada.; High throughput screening platform, Montréal, QC, Canada., Mathien S; Institute for Research in Immunology and Cancer, Montréal, QC, Canada.; High throughput screening platform, Montréal, QC, Canada., Bonneil É; Institute for Research in Immunology and Cancer, Montréal, QC, Canada.; Proteomics and Bioanalytical Mass Spectrometry Research Unit, Montréal, QC, Canada., Eppert K; Centre for Translational Biology, McGill University Heath Centre Research Institute, Montréal, QC, Canada.; Department of Pediatrics, McGill University, Montréal, QC, Canada., Marinier A; Institute for Research in Immunology and Cancer, Montréal, QC, Canada.; Medicinal Chemistry/Drug Discovery Unit, Montréal, QC, Canada.; Department of Chemistry, Université de Montréal, Montréal, QC, Canada., Sauvageau G; Institute for Research in Immunology and Cancer, Montréal, QC, Canada.; Molecular Genetics of Stem Cells Research Unit, Montréal, QC, Canada.; Institut universitaire d'hémato-oncologie et de thérapie cellulaire, Maisonneuve-Rosemont Hospital, Montréal, QC, Canada.; Quebec Leukemia Cell Bank, Maisonneuve-Rosemont Hospital Research Center, Montréal, QC, Canada.; Department of Medicine, Faculty of Medicine, Université de Montréal, Montréal, QC, Canada., Deblois G; Institute for Research in Immunology and Cancer, Montréal, QC, Canada.; Faculty of Medicine, Faculty of Pharmacy, University of Montréal, Montréal, QC, Canada., Thibault P; Institute for Research in Immunology and Cancer, Montréal, QC, Canada.; Proteomics and Bioanalytical Mass Spectrometry Research Unit, Montréal, QC, Canada.; Department of Chemistry, Faculty of Arts and Sciences, Université de Montréal, Montréal, QC, Canada., Hébert J; Institut universitaire d'hémato-oncologie et de thérapie cellulaire, Maisonneuve-Rosemont Hospital, Montréal, QC, Canada.; Quebec Leukemia Cell Bank, Maisonneuve-Rosemont Hospital Research Center, Montréal, QC, Canada.; Department of Medicine, Faculty of Medicine, Université de Montréal, Montréal, QC, Canada., Eaves CJ; Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, BC, Canada.; Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada., Cellot S; Unité de recherche en immuno-hémato-oncologie Charles-Bruneau, Centre de recherche Azrieli du CHU Sainte-Justine, Montréal, QC, Canada. sonia.cellot@umontreal.ca.; Faculty of Medicine, Université de Montréal, Montréal, QC, Canada. sonia.cellot@umontreal.ca., Barabé F; Centre de recherche en infectiologie du CHUL, Centre de recherche du CHU de Québec - Université Laval, Québec City, QC, Canada. Frederic.Barabe@crchudequebec.ulaval.ca.; Department of Medicine, Université Laval, Quebec City, QC, Canada. Frederic.Barabe@crchudequebec.ulaval.ca., Wilhelm BT; Laboratory for High Throughput Biology, Montréal, QC, Canada. brian.wilhelm@umontreal.ca.; Institute for Research in Immunology and Cancer, Montréal, QC, Canada. brian.wilhelm@umontreal.ca.; Department of Medicine, Faculty of Medicine, Université de Montréal, Montréal, QC, Canada. brian.wilhelm@umontreal.ca.

Publikováno v: Leukemia [Leukemia] 2024 Oct 29. Date of Electronic Publication: 2024 Oct 29.