Zobrazeno 1 - 10
of 358
pro vyhledávání: '"Soudijn W"'
Publikováno v:
Journal of Medicinal Chemistry. 38:4303-4308
A series of unsubstituted and substituted succinimido, maleimido, and glutarimidoethyl derivatives of eltoprazine (3) was synthesized and tested for affinity for the 5-HT 1A receptor in rat brain homogenates. The unsubstituted compounds have a modera
Publikováno v:
Progress in Drug Research ISBN: 9783034895460
An overview is presented on progress made in the research on neuronal transporters of serotonin, dopamine and norepinephrine in the central nervous system. Tools developed by molecular biology, such as expression of cloned transporters, their mutants
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44f2e623e5343bbb98ea66710f82b6a6
https://doi.org/10.1007/978-3-0348-8391-7_3
https://doi.org/10.1007/978-3-0348-8391-7_3
Publikováno v:
Journal of pharmacology and experimental therapeutics, 279(3), 1439-1446. American Society for Pharmacology and Experimental Therapeutics
The cardiovascular effects of the nonselective adenosine receptor agonist 8-butylaminoadenosine (BAA) were quantified in conscious normotensive rats. The potency and intrinsic activity for the A1 and A2a receptor were determined separately. The rats
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=narcis______::8ca6946e4cfc652e05f94f2c01468768
https://pure.amc.nl/en/publications/partial-agonism-of-the-nonselective-adenosine-receptor-agonist-8butylaminoadenosine-at-the-a1-receptor-in-vivo(84f78da5-33d2-4264-95d1-091c5c17eaa8).html
https://pure.amc.nl/en/publications/partial-agonism-of-the-nonselective-adenosine-receptor-agonist-8butylaminoadenosine-at-the-a1-receptor-in-vivo(84f78da5-33d2-4264-95d1-091c5c17eaa8).html
Publikováno v:
Europe PubMed Central
The purpose of the present study was to quantify the in vivo potency of the selective adenosine A2a antagonist CSC [8-(3-chlorostyryl)caffeine]. Four groups of conscious, normotensive rats received a continuous i.v. infusion of 0, 6, 12 and 24 μg/mi
Autor:
Mathôt, R. A., van den Aarsen, B. C., Soudijn, W., Breimer, D. D., IJzerman, A. P., Danhof, M.
Publikováno v:
Journal of pharmacology and experimental therapeutics, 273(1), 405-414. American Society for Pharmacology and Experimental Therapeutics
Recently, the commercially available adenosine receptor agonist S-N6-phenylisopropyladenosine (S-PIA) has been demonstrated to be contaminated with the more potent R-diastereomer. The potency of S-PIA may therefore have been overestimated in previous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=narcis______::65c46e813f83eddda316e09ac84e0385
https://pure.amc.nl/en/publications/pharmacokineticpharmacodynamic-modelling-of-the-cardiovascular-effects-of-r-and-sn6phenylisopropyladenosine-in-conscious-normotensive-rats(447c2453-9605-40eb-bcd1-d57c3fcbb53b).html
https://pure.amc.nl/en/publications/pharmacokineticpharmacodynamic-modelling-of-the-cardiovascular-effects-of-r-and-sn6phenylisopropyladenosine-in-conscious-normotensive-rats(447c2453-9605-40eb-bcd1-d57c3fcbb53b).html
Publikováno v:
Europe PubMed Central
The purpose of the investigation was to develop a pharmacokinetic-pharmacodynamic model for the characterization of the cardiovascular effects of the adenosine A1 receptor agonist N6-cyclopentyladenosine (CPA) in individual normotensive rats. After t
Autor:
Mathôt, R. A., van Schaick, E. A., Langemeijer, M. W., Soudijn, W., Breimer, D. D., IJzerman, A. P., Danhof, M.
Publikováno v:
Journal of pharmacology and experimental therapeutics, 268(2), 616-624. American Society for Pharmacology and Experimental Therapeutics
The purpose of the investigation was to develop a pharmacokinetic-pharmacodynamic model for the characterization of the cardiovascular effects of the adenosine A1 receptor agonist N6-cyclopentyladenosine (CPA) in individual normotensive rats. After t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=narcis______::5f7c25d3e0e5164e264ba90f1584665f
https://pure.amc.nl/en/publications/pharmacokineticpharmacodynamic-relationship-of-the-cardiovascular-effects-of-adenosine-a1-receptor-agonist-n6cyclopentyladenosine-in-the-rat(418d0f10-1f5b-4294-8e56-447bcec847e2).html
https://pure.amc.nl/en/publications/pharmacokineticpharmacodynamic-relationship-of-the-cardiovascular-effects-of-adenosine-a1-receptor-agonist-n6cyclopentyladenosine-in-the-rat(418d0f10-1f5b-4294-8e56-447bcec847e2).html
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