Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Souad Diana Tork"'
Autor:
Souad Diana Tork, Mădălina Elena Moisă, Lilla Cserepes, Alina Filip, Levente Csaba Nagy, Florin Dan Irimie, László Csaba Bencze
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Unnatural substituted amino acids play an important role as chiral building blocks, especially for pharmaceutical industry, where the synthesis of chiral biologically active molecules still represents an open challenge. Recently, modificatio
Externí odkaz:
https://doaj.org/article/a1ac952428c94f1ea4e20017a24a8f9e
Autor:
Raluca Bianca Tomoiagă, Souad Diana Tork, Ilka Horváth, Alina Filip, Levente Csaba Nagy, László Csaba Bencze
Publikováno v:
Biomolecules, Vol 10, Iss 6, p 838 (2020)
Phenylalanine ammonia-lyases (PALs) are attractive biocatalysts for the stereoselective synthesis of non-natural phenylalanines. The rational design of PALs with extended substrate scope, highlighted the substrate specificity-modulator role of residu
Externí odkaz:
https://doaj.org/article/c32d4e32defd493da21a30ab83933775
Autor:
Raluca Bianca Tomoiagă, Souad Diana Tork, Alina Filip, Levente Csaba Nagy, László Csaba Bencze
Publikováno v:
Applied Microbiology and Biotechnology. 107:1243-1256
Publikováno v:
The Journal of Organic Chemistry. 88:852-862
Publikováno v:
The Journal of organic chemistry.
An efficient preparative-scale synthetic procedure of l-phenylalanine derivatives has been developed using mutant variants of phenylalanine ammonia-lyase from
Autor:
László Csaba Bencze, Florin D. Irimie, László Poppe, Souad Diana Tork, Alina Filip, Emma Z. A. Nagy, Csaba Paizs, Gergely Bánóczi, Monica Ioana Toşa
Publikováno v:
Chemcatchem
Tailored mutants of phenylalanine ammonia‐lyase from Petroselinum crispum (PcPAL) were created and tested in ammonia elimination from various sterically demanding, non‐natural analogues of phenylalanine and in ammonia addition reactions into the
Autor:
Florin D. Irimie, László Poppe, László Csaba Bencze, Jürgen Brem, Christopher J. Schofield, Monica Ioana Toşa, Souad Diana Tork, Emma Z. A. Nagy, Csaba Paizs, Pauline A. Lang, Alina Filip
Publikováno v:
ACS Catalysis.
Modification of the hydrophobic binding pocket of phenylalanine ammonia-lyase from Petroselinum crispum (PcPAL) enables increased activity and selectivity towards phenylalanines and cinnamic acids mono-substituted with both electron donating (-CH3, -