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Publikováno v:
ACS Synthetic Biology. 11:3973-3985
Changing the substrate/cofactor specificity of an enzyme requires multiple mutations at spatially adjacent positions around the substrate pocket. However, this is challenging when solely based on crystal structure information because enzymes undergo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cc420de04dcaca72ff1c071d6ac76f1
https://doi.org/10.1021/acssynbio.2c00315
https://doi.org/10.1021/acssynbio.2c00315
