Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Sou Sakamoto"'
Publikováno v:
SLAS Discovery, Vol 28, Iss 7, Pp 344-349 (2023)
The beta-glucocerebrosidase (GBA1) gene encodes the lysosomal beta-glucocerebrosidase (GCase) that metabolizes the lipids glucosylceramide (GlcCer) and glucosylsphingosine (GlcSph). Biallelic loss-of-function mutations in GBA1 such as L444P cause Gau
Externí odkaz:
https://doaj.org/article/6fa5022fc3904bd99b6d9e7cc05d8004
Publikováno v:
Journal of General and Family Medicine
Autor:
Takahito Hara, Satoshi Kitazawa, Misa Iwatani, Hitoshi Miyashita, Ryutaro Adachi, Yukiko Yamamoto, Megumi Morimoto, Takeo Arita, Sou Sakamoto, Takaharu Hirayama, Kazumasa Miyamoto
Publikováno v:
Biochemical and Biophysical Research Communications. 488:648-654
Protein translation is highly activated in cancer tissues through oncogenic mutations and amplifications, and this can support survival and aberrant proliferation. Therefore, blocking translation could be a promising way to block cancer progression.
Autor:
Takayuki Komatsu, Tomohisa Nomura, Sou Sakamoto, Hajime Sekii, Hiroki Takami, Manabu Sugita, Keiko Mizuno
Publikováno v:
Juntendo Medical Journal. 60:132-136
Autor:
Kouhei Tsumoto, Emiko Sano, Yoshikazu Tanaka, Sou Sakamoto, Jose M. M. Caaveiro, Motonori Kudou
Publikováno v:
Journal of Molecular Biology. 389:880-894
Human interleukin 15 (hIL15) is a soluble cytokine that plays a key role in the maintenance of long-lasting responses against pathogens and a valuable target for the treatment of autoimmune diseases. In this study, we sought to elucidate the thermody
Autor:
Min Yao, Toshiko Ohta, Sou Sakamoto, Kouhei Tsumoto, Toshiaki Takei, Yoshikazu Tanaka, Makoto Kuroda, Isao Tanaka, Jian Yu
Publikováno v:
Biochemical and Biophysical Research Communications. 376:261-266
Ebh, a giant protein found in staphylococci, contains several domains, including a large central region with 52 imperfect repeats of a domain composed of 126 amino acids. We used electron microscopy to observe the rod-like structure of a partial Ebh
Autor:
Kouhei Tsumoto, Nobuhisa Watanabe, Yoshikazu Tanaka, Isao Tanaka, Makoto Kuroda, Yong-Gui Gao, Shuichiro Goda, Yuzuru Hiragi, Toshiko Ohta, Min Yao, Sou Sakamoto
Publikováno v:
Structure (London, England : 1993). 16(3)
SummaryThe 1.1 MDa cell-wall-associated adhesion protein of staphylococci, Ebh, consists of several distinct regions, including a large central region with 52 imperfect repeats of 126 amino acid residues. We investigated the structure of this giant m
Publikováno v:
Chemistry Letters. 37:556-557
Farnesol and geraniol were glucosylated to the corresponding unnatural β-glucosides, which were two new biotransformation products, by cultured plant cells of Eucalyptus perriniana, Strophanthus gr...
Autor:
Akiyama, Tomohiko, Sato, Saeko, Ko, Shigeru B. H., Sano, Osamu, Sato, Sho, Saito, Masayo, Nagai, Hiroaki, Ko, Minoru S. H., Iwata, Hidehisa
Publikováno v:
Stem Cells Translational Medicine; Apr2021, Vol. 10 Issue 4, p572-581, 10p
Publikováno v:
Drug Week; 11/17/2023, p626-626, 1p