Zobrazeno 1 - 10
of 529
pro vyhledávání: '"Sotorasib"'
Autor:
Warnecke B, Nagasaka M
Publikováno v:
Drug Design, Development and Therapy, Vol Volume 18, Pp 5673-5683 (2024)
Brian Warnecke,1 Misako Nagasaka1,2 1Department of Medicine, University of California Irvine School of Medicine, Chao Family Comprehensive Cancer Center, Orange, CA, USA; 2Department of Medicine, St. Marianna University School of Medicine, Kawasaki,
Externí odkaz:
https://doaj.org/article/0efa164d82a54a04a5e3ddc403c610dd
Autor:
Ofra Novoplansky, Sankar Jagadeeshan, Manu Prasad, Ksenia M. Yegodayev, Divyasree Marripati, Raghda Abu Shareb, Yariv Greenshpan, Sooraj Mathukkada, Talal Ben-Lulu, Baisali Bhattacharya, Angel Porgador, Dexin Kong, Johannes Brägelmann, J. Silvio Gutkind, Moshe Elkabets
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-23 (2024)
Abstract Background Basket clinical trials targeting the KRASG12C-mutation in solid tumors have shown initial promise, including in orphan KRASG12C head and neck cancer (HNC). However, development of resistance to KRASG12C-mutant-specific inhibitors
Externí odkaz:
https://doaj.org/article/c4597987045c4368ad8d1ce46434bbc8
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Lung cancer remains a significant health challenge, characterized by aberrant tissue growth within the pulmonary system. Early carcinogenic events often involve genomic instability and the emergence of a mutator phenotype. In this study, we
Externí odkaz:
https://doaj.org/article/0db7784893b04f35bcd86368efa78a37
Publikováno v:
Lung Cancer: Targets and Therapy, Vol Volume 15, Pp 161-167 (2024)
Faustine X Luo,1,2 Zhaohui Liao Arter1,2 1University of California Irvine School of Medicine, Orange, CA, 92868, USA; 2Chao Family Comprehensive Cancer Center, Orange, CA, 92868, USACorrespondence: Zhaohui Liao Arter, Department of Medicine, Division
Externí odkaz:
https://doaj.org/article/75717a59611c403781716c7eb4bd2f5d
Publikováno v:
Case Reports in Oncology, Vol 17, Iss 1, Pp 1019-1024 (2024)
Introduction: Pulmonary sarcomatoid carcinomas (PSCs) are a rare subgroup of non-small cell lung cancer (NSCLC). In contrast to other NSCLCs, PSCs have a poor prognosis due to limited efficacy of radiation and chemotherapy. Therefore, other therapeut
Externí odkaz:
https://doaj.org/article/e9aeacf3b12541dba69d6d6178168d3b
Publikováno v:
Results in Chemistry, Vol 11, Iss , Pp 101799- (2024)
Sotorasib is a small molecule inhibitor and approved by USFDA for the treatment of non-small cell lung cancer (NSCLC). In the present study, forced degradation behavior of sotorasib was carried out by utilizing LC-MS/MS technique. As per ICH guidelin
Externí odkaz:
https://doaj.org/article/c3700359cad242d2aa10ea514a87e7ed
Publikováno v:
Forum of Clinical Oncology, Vol 14, Iss 2, Pp 3-6 (2024)
Drug dosing based on the body surface area (BSA) has been the mainstay of oncological treatment over the last decades. Although this seems to be an adequate measure of an individual’s appropriate dose for traditional chemotherapeutic drugs accordin
Externí odkaz:
https://doaj.org/article/f6082acdab59410288d5b77585fdb595
Autor:
K. K. Laktionov, K. A. Sarantseva, L. A. Nelyubina, S. V. Gamayunov, E. A. Kolesnikova, M. G. Gordiev
Publikováno v:
Сибирский онкологический журнал, Vol 23, Iss 2, Pp 72-81 (2024)
Lung cancer remains one of the most dangerous and most common cancers, requiring constant improvement of diagnostic and treatment methods. The genetic heterogeneity of lung cancer forces us to search for new therapeutic targets in an attempt to achie
Externí odkaz:
https://doaj.org/article/73b447e88d214b60aa826941c8d2573c
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-4 (2024)
Externí odkaz:
https://doaj.org/article/d42b8804529649f09f876df2d4f83483
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