Zobrazeno 1 - 10
of 691
pro vyhledávání: '"Soto-Gutierrez A"'
Autor:
Julio Aleman, Ravikumar K, Connor Wiegand, Mark E. Schurdak, Lawrence Vernetti, Dillon Gavlock, Celeste Reese, Richard DeBiasio, Greg LaRocca, Yulder Daniel Angarita, Albert Gough, Alejandro Soto-Gutierrez, Jaideep Behari, Vijay K. Yechoor, Mark T. Miedel, Andrew M. Stern, Ipsita Banerjee, D. Lansing Taylor
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-14 (2024)
Abstract Preclinical and clinical studies suggest that lipid-induced hepatic insulin resistance is a primary defect that predisposes to dysfunction in islets, implicating a perturbed liver-pancreas axis underlying the comorbidity of T2DM and MASLD. T
Externí odkaz:
https://doaj.org/article/3786b7dd0e8e47af8bbe42c89dff77b0
Autor:
Zhiping Hu, Takeshi Kurihara, Yiyue Sun, Zeliha Cetin, Rodrigo M. Florentino, Lanuza A. P. Faccioli, Zhenghao Liu, Bo Yang, Alina Ostrowska, Joseph D. Locker, Alejandro Soto-Gutierrez, Evan R. Delgado
Publikováno v:
Frontiers in Gastroenterology, Vol 3 (2024)
Hepatocellular carcinoma (HCC) is a leading cause of cancer-related deaths, and commonly associated with hepatic fibrosis or cirrhosis. This study aims to establish a rat model mimicking the progression from liver fibrosis to cirrhosis and subsequent
Externí odkaz:
https://doaj.org/article/0ba87285b6114e80a427824b190da594
Autor:
Mengying Xia, Mahboubeh Varmazyad, Iris Pla-Palacín, Dillon C. Gavlock, Richard DeBiasio, Gregory LaRocca, Celeste Reese, Rodrigo M. Florentino, Lanuza A. P. Faccioli, Jacquelyn A. Brown, Lawrence A. Vernetti, Mark Schurdak, Andrew M. Stern, Albert Gough, Jaideep Behari, Alejandro Soto-Gutierrez, D. Lansing Taylor, Mark T. Miedel
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Metabolic dysfunction-associated steatotic liver disease (MASLD) is a worldwide health epidemic with a global occurrence of approximately 30%. The pathogenesis of MASLD is a complex, multisystem disorder driven by multiple factors, including genetics
Externí odkaz:
https://doaj.org/article/ee7744aae33d4960a923808275c298d0
Autor:
Zehra N. Kocas-Kilicarslan, Zeliha Cetin, Lanuza A.P. Faccioli, Takashi Motomura, Sriram Amirneni, Ricardo Diaz-Aragon, Rodrigo M. Florentino, Yiyue Sun, Iris Pla-Palacin, Mengying Xia, Mark T. Miedel, Takeshi Kurihara, Zhiping Hu, Alina Ostrowska, Zi Wang, Robert Constantine, Albert Li, D. Lansing Taylor, Jaideep Behari, Alejandro Soto-Gutierrez, Edgar N. Tafaleng
Publikováno v:
Gastro Hep Advances, Vol 3, Iss 1, Pp 67-77 (2024)
Background and Aims: Chronic liver injury that results in cirrhosis and end-stage liver disease (ESLD) causes more than 1 million deaths annually worldwide. Although the impact of genetic factors on the severity of metabolic dysfunction-associated st
Externí odkaz:
https://doaj.org/article/a352c00a654e49048cd6eb2ec5a1d2e4
Autor:
Kocas-Kilicarslan, Zehra N., Cetin, Zeliha, Faccioli, Lanuza A.P., Motomura, Takashi, Amirneni, Sriram, Diaz-Aragon, Ricardo, Florentino, Rodrigo M., Sun, Yiyue, Pla-Palacin, Iris, Xia, Mengying, Miedel, Mark T., Kurihara, Takeshi, Hu, Zhiping, Ostrowska, Alina, Wang, Zi, Constantine, Robert, Li, Albert, Taylor, D. Lansing, Behari, Jaideep, Soto-Gutierrez, Alejandro, Tafaleng, Edgar N.
Publikováno v:
In Gastro Hep Advances 2024 3(1):67-77
Autor:
Silvia Liu, Yan-Ping Yu, Bao-Guo Ren, Tuval Ben-Yehezkel, Caroline Obert, Mat Smith, Wenjia Wang, Alina Ostrowska, Alejandro Soto-Gutierrez, Jian-Hua Luo
Publikováno v:
eLife, Vol 12 (2024)
The protein diversity of mammalian cells is determined by arrays of isoforms from genes. Genetic mutation is essential in species evolution and cancer development. Accurate long-read transcriptome sequencing at single-cell level is required to deciph
Externí odkaz:
https://doaj.org/article/23e99210857f4a04b3e00be99733567f
Autor:
Kimberly Ortiz, Zeliha Cetin, Yiyue Sun, Zhiping Hu, Takeshi Kurihara, Edgar N. Tafaleng, Rodrigo M. Florentino, Alina Ostrowska, Alejandro Soto-Gutierrez, Lanuza A.P. Faccioli
Publikováno v:
Organogenesis, Vol 19, Iss 1 (2023)
ABSTRACTPrimary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC), the most common types of cholestatic liver disease (CLD), result in enterohepatic obstruction, bile acid accumulation, and hepatotoxicity. The mechanisms by which hep
Externí odkaz:
https://doaj.org/article/474ad1eb458e4832bae349ddc7a20857
Autor:
Rizvi, Fatima, Lee, Yu-Ri, Diaz-Aragon, Ricardo, Bawa, Pushpinder S., So, Juhoon, Florentino, Rodrigo M., Wu, Susan, Sarjoo, Arianna, Truong, Emily, Smith, Anna R., Wang, Feiya, Everton, Elissa, Ostrowska, Alina, Jung, Kyounghwa, Tam, Ying, Muramatsu, Hiromi, Pardi, Norbert, Weissman, Drew, Soto-Gutierrez, Alejandro, Shin, Donghun, Gouon-Evans, Valerie
Publikováno v:
In Cell Stem Cell 7 December 2023 30(12):1640-1657
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Akademický článek
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