Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Sotiris Lakis"'
Autor:
Vassiliki Kotoula, Sotiris Lakis, Ioannis S Vlachos, Eleni Giannoulatou, Flora Zagouri, Zoi Alexopoulou, Helen Gogas, Dimitrios Pectasides, Gerasimos Aravantinos, Ioannis Efstratiou, George Pentheroudakis, Kyriaki Papadopoulou, Kyriakos Chatzopoulos, Pavlos Papakostas, Maria Sotiropoulou, Irene Nicolaou, Evangelia Razis, Amanda Psyrri, Paris Kosmidis, Christos Papadimitriou, George Fountzilas
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0163138 (2016)
Stromal tumor infiltrating lymphocytes (TILs) density is an outcome predictor in triple-negative breast cancer (TNBC). Herein we asked whether TILs are related to coding mutation load and to the chemical class of the resulting mutated amino acids, i.
Externí odkaz:
https://doaj.org/article/c22d07cc557b4f04882d649c66ff7d85
Autor:
Vassiliki Kotoula, Aggeliki Lyberopoulou, Kyriaki Papadopoulou, Elpida Charalambous, Zoi Alexopoulou, Chryssa Gakou, Sotiris Lakis, Eleftheria Tsolaki, Konstantinos Lilakos, George Fountzilas
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0128818 (2015)
Massively parallel sequencing (MPS) holds promise for expanding cancer translational research and diagnostics. As yet, it has been applied on paraffin DNA (FFPE) with commercially available highly multiplexed gene panels (100s of DNA targets), while
Externí odkaz:
https://doaj.org/article/aee2dfaae82049d791365de507171c0d
Autor:
Ralph M. Wirtz, George Pentheroudakis, Elpida Charalambous, Flora Zagouri, Kyriaki Papadopoulou, Vassiliki Kotoula, Eleftheria Tsolaki, Eleni Timotheadou, Angelos Koutras, Sotiris Lakis, Zoi Alexopoulou, George Fountzilas, Aggeliki Lyberopoulou, Dimitrios Pectasides, Konstantine T. Kalogeras, Helen Gogas
Publikováno v:
Cancer Research. 75:P5-10
Background - Aim: Malignant tumors are currently understood as genetic mosaics. For breast cancer (BC) patient assessment, the challenge remains to use the increasingly available tumor genomic data along with standard clinicopathological parameters.
Autor:
Ioannis Efstratiou, George Fountzilas, Sofia Chrisafi, Anna Batistatou, Olympia Tzaida, Eleni Timotheadou, Petroula Arapantoni-Dadioti, Flora Zagouri, Triantafyllia Koletsa, Sotiris Lakis, Dimitrios Pectasides, Georgia Gourgioti, Eleftheria Tsolaki, Alexandra Papoudou-Bai, Mattheos Bobos, Helen Gogas, Elena Fountzilas
Publikováno v:
Cancer Research. 75:P3-09
Background-Aim: The aim of the present study was to explore the efficacy of dose-dense sequential adjuvant chemotherapy followed by trastuzumab in HER2-positive patients according to the immunohistochemically (IHC) defined subtypes. Patients and meth
Autor:
George Fountzilas, Ioannis Kostopoulos, Ioannis Kaklamanos, Kyriaki Papadopoulou, Helen Gogas, Kyriakos Koukoulias, Grigorios Rallis, Pavlos Papakostas, Dimitrios Bafaloukos, Dimitrios Pectasides, Sotiris Lakis, Vassiliki Kotoula, Evangelia Razis, Sofia Levva, Christos Papadimitriou, Kyriaki Manousou, Vasilios Karavasilis, Gerasimos Aravantinos, Flora Zagouri, Eufemia Balassi, George Pentheroudakis
Publikováno v:
Cancer genomicsproteomics. 14(3)
Background: Epidermal growth factor receptor (EGFR) aberrations have been implicated in the pathogenesis of triple-negative breast cancer (TNBC) but their impact on prognosis and, therefore, druggability, remain controversial. Herein, we studied EGFR
Autor:
Paris Kosmidis, Amanda Psyrri, Irene Nicolaou, Gerasimos Aravantinos, Flora Zagouri, George Pentheroudakis, Zoi Alexopoulou, Sotiris Lakis, Christos Papadimitriou, Evangelia Razis, Ioannis Efstratiou, George Fountzilas, Vassiliki Kotoula, Eleni Giannoulatou, Ioannis S. Vlachos, Dimitrios Pectasides, Kyriakos Chatzopoulos, Kyriaki Papadopoulou, Pavlos Papakostas, Maria Sotiropoulou, Helen Gogas
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 9, p e0163138 (2016)
PLoS ONE, Vol 11, Iss 9, p e0163138 (2016)
Background Stromal tumor infiltrating lymphocytes (TILs) density is an outcome predictor in triple-negative breast cancer (TNBC). Herein we asked whether TILs are related to coding mutation load and to the chemical class of the resulting mutated amin
Autor:
Rodney J. Scott, J. Louise Jones, Janet E. Olson, Wei Zheng, Drakoulis Yannoukakos, Fergus J. Couch, Ute Hamann, Carl Blomqvist, Veli-Matti Kosma, Judy Gilbert, Maria Kabisch, Graham G. Giles, Melissa C. Southey, Thomas Rüdiger, Sandra Deming-Halverson, Arto Mannermaa, Jeanette E. Eckel-Passow, Celine M. Vachon, Chen Wang, Vassiliki Kotoula, Angela Cox, Jane Carpenter for Abctc Investigators, George Fountzilas, Simon S. Cross, Päivi Heikkilä, Sotiris Lakis, Kristen S. Purrington, Christine L. Clarke, Diana Eccles, Daniel W. Visscher, Heli Nevanlinna
Distinct subtypes of triple negative (TN) breast cancer have been identified by tumor expression profiling. However, little is known about the relationship between histopathologic features of TN tumors, which reflect aspects of both tumor behavior an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43b8ca9bafb76f5e33d857ce70cae680
http://hdl.handle.net/10138/224013
http://hdl.handle.net/10138/224013
Autor:
Laible, Mark, Schlombs, Kornelia, Kaiser, Katharina, Veltrup, Elke, Herlein, Stefanie, Sotiris Lakis, Stรถhr, Robert, Eidt, Sebastian, Hartmann, Arndt, Wirtz, Ralph, Ugur Sahin
A: RNA and DNA concentrations in RNXtract eluates, B: Analyte specificity data, C: Graphical representation of variance components. (DOCX 125 kb)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbdf5353dbd869d4128c59a6bfb06da4
Autor:
Elke Veltrup, Sotiris Lakis, Ralph M. Wirtz, Sebastian Eidt, Ugur Sahin, Stefanie Herlein, Kornelia Schlombs, Katharina Kaiser, Robert Stöhr, Mark Laible, Arndt Hartmann
Publikováno v:
BMC Cancer
Background MammaTyper is a novel CE-marked in vitro diagnostic RT-qPCR assay which assigns routinely processed breast cancer specimens into the molecular subtypes Luminal A-like, Luminal B-like (HER2 positive or negative), HER2 positive (non-luminal)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f53e9d2a6949d150b21df8a11a2fd8b9
https://opus4.kobv.de/opus4-fau/frontdoor/index/index/docId/8002
https://opus4.kobv.de/opus4-fau/frontdoor/index/index/docId/8002
Autor:
Helen Gogas, K. Manousou, Vasiliki Kotoula, Ioannis Tikas, Sotiris Lakis, Angelos Koutras, Georgios Pentheroudakis, G. Fountzilas, Dimitris Bafaloukos, D.G. Pectasides, Flora Zagouri, Christos N. Papandreou, Kyriaki Papadopoulou, Eleni Giannoulatou, Ioannis Efstratiou, Mattheos Bobos, A. Psyrri, Pavlos Papakostas, C. Christodoulou, Georgios Lazaridis
Publikováno v:
Annals of Oncology. 28:v55-v56