Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Sotiris, Kyriakou"'
Autor:
Ioannis Anestopoulos, Ioannis Paraskevaidis, Sotiris Kyriakou, Lambrini E. Giova, Dimitrios T. Trafalis, Sotiris Botaitis, Rodrigo Franco, Aglaia Pappa, Mihalis I. Panayiotidis
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 5, p 2745 (2024)
In this study, we utilized an in vitro model consisting of human malignant melanoma as well as non-tumorigenic immortalized keratinocyte cells with the aim of characterizing the therapeutic effectiveness of the clinical epigenetic drug Tazemetostat a
Externí odkaz:
https://doaj.org/article/e8e1e020d2b84d4e8491814b20a58b7e
Autor:
Sotiris Kyriakou, Nikoletta Demosthenous, Tom Amery, Kyle J. Stewart, Paul G. Winyard, Rodrigo Franco, Aglaia Pappa, Mihalis I. Panayiotidis
Publikováno v:
Antioxidants, Vol 13, Iss 1, p 82 (2024)
Phenethyl isothiocyanate (PEITC) is a secondary metabolic product yielded upon the hydrolysis of gluconasturtiin and it is highly accumulated in the flowers of watercress. The aim of the current study was to assess the role of a naturally derived PEI
Externí odkaz:
https://doaj.org/article/2d6cf5720aac4d71821fc712fd477ed6
Autor:
Sotiris Kyriakou, Louiza Potamiti, Nikoletta Demosthenous, Tom Amery, Kyle Stewart, Paul G. Winyard, Rodrigo Franco, Aglaia Pappa, Mihalis I. Panayiotidis
Publikováno v:
Nutrients, Vol 15, Iss 18, p 4044 (2023)
The aim of the current study was to (i) extract isolated fractions of watercress flowers enriched in polyphenols, phenethyl isothiocyanate and glucosinolates and (ii) characterize the anticancer mode of action of non-lethal, sub-lethal and lethal con
Externí odkaz:
https://doaj.org/article/dc154627d0954d9187365deb43eff9e3
Autor:
Antonis Ververis, Sotiris Kyriakou, Kristia Ioannou, Paschalina S. Chatzopoulou, Mihalis I. Panayiotidis, Michael Plioukas, Kyproula Christodoulou
Publikováno v:
Plants, Vol 12, Iss 18, p 3191 (2023)
An increasingly common ailment in elderly persons is Alzheimer’s disease (AD), a neurodegenerative illness. Present treatment is restricted to alleviating symptoms; hence, there is a requirement to develop an effective approach to AD treatment. Sal
Externí odkaz:
https://doaj.org/article/4cf13ff49a1043489af2fe36057102be
Autor:
Sotiris Kyriakou, Kyriaki Michailidou, Tom Amery, Kyle Stewart, Paul G. Winyard, Dimitrios T. Trafalis, Rodrigo Franco, Aglaia Pappa, Mihalis I. Panayiotidis
Publikováno v:
Frontiers in Plant Science, Vol 13 (2022)
Watercress (Nasturtium officinale) is a rich source of secondary metabolites with disease-preventing and/or health-promoting properties. Herein, we have utilized extraction procedures to isolate fractions of polyphenols, glucosinolates and isothiocya
Externí odkaz:
https://doaj.org/article/bc058b1b57d64b9e85f7fad606de1873
Autor:
Sotiris Kyriakou, Venetia Tragkola, Ioannis Paraskevaidis, Mihalis Plioukas, Dimitrios T. Trafalis, Rodrigo Franco, Aglaia Pappa, Mihalis I. Panayiotidis
Publikováno v:
Plants, Vol 12, Iss 8, p 1590 (2023)
Malignant melanoma is an aggressive type of skin cancer characterised by high metastatic capacity and mortality rate. On the other hand, Epilobium parviflorum is known for its medicinal properties, including its anticancer potency. In this context, w
Externí odkaz:
https://doaj.org/article/4d7ef4ce73a5491a96acb88eb79b9dee
Autor:
Antonis Ververis, Kristia Ioannou, Sotiris Kyriakou, Niki Violaki, Mihalis I. Panayiotidis, Michael Plioukas, Kyproula Christodoulou
Publikováno v:
Plants, Vol 12, Iss 8, p 1716 (2023)
Alzheimer’s disease (AD) is the most prevalent neurodegenerative condition, primarily affecting seniors. Despite the significant time and money spent over the past few decades, no therapy has been developed yet. In recent years, the research has fo
Externí odkaz:
https://doaj.org/article/eb4be2cec4f646f48ff58d135e30940b
Autor:
Katerina Spyridopoulou, Sotiris Kyriakou, Angeliki Nomikou, Angelos Roupas, Antreas Ermogenous, Katerina Karamanoli, Daniela Moyankova, Dimitar Djilianov, Alex Galanis, Mihalis I. Panayiotidis, Aglaia Pappa
Publikováno v:
Antioxidants, Vol 11, Iss 12, p 2305 (2022)
Haberlea rhodopensis is a Balkan endemic plant that belongs to the Gesneriaceae family, and is believed to have medicinal use and health-promoting properties. This study aimed to (i) prepare aqueous (HAE) and ethanolic (HEE) extracts from the leaves
Externí odkaz:
https://doaj.org/article/8c7f71f7e7e84a1eab3cdd3a182a6883
Autor:
Sotiris Kyriakou, Dimitrios T. Trafalis, Maria V. Deligiorgi, Rodrigo Franco, Aglaia Pappa, Mihalis I. Panayiotidis
Publikováno v:
Antioxidants, Vol 11, Iss 4, p 642 (2022)
Isothiocyanates are biologically active secondary metabolites liberated via enzymatic hydrolysis of their sulfur enriched precursors, glucosinolates, upon tissue plant disruption. The importance of this class of compounds lies in their capacity to in
Externí odkaz:
https://doaj.org/article/89685edcb49149e686987a71a2dda3c6
Autor:
Sotiris Kyriakou, Venetia Tragkola, Heba Alghol, Ioannis Anestopoulos, Tom Amery, Kyle Stewart, Paul G. Winyard, Dimitrios T. Trafalis, Rodrigo Franco, Aglaia Pappa, Mihalis I. Panayiotidis
Publikováno v:
Pharmaceuticals, Vol 15, Iss 2, p 141 (2022)
Watercress is an enriched source of phenethyl isothiocyanate (PEITC), among other phytochemicals, with an antioxidant capacity. The aim of this study was to (i) chemically characterize and (ii) biologically evaluate the profile of the main health-pro
Externí odkaz:
https://doaj.org/article/cbf0416506534de384e72ca504df6d0d