Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Sota Katayama"'
Autor:
Yusuke Oku, Naoyuki Nishiya, Sota Katayama, Yoshimasa Uehara, Tomoko Sakyo, Mami Ogawa, Norikazu Omori, Honami Yonezawa, Yui Shimizu
Publikováno v:
Biochemical and Biophysical Research Communications. 506:183-188
The Wnt/β-catenin signaling pathway controls cell proliferation and differentiation, and therefore, when this pathway is excessively activated, it causes tumorigenesis. Our chemical suppressor screening in zebrafish embryos identified antifungal azo
Publikováno v:
Chemistry Letters. 47:1116-1118
A concise procedure to prepare optically active (3R)- and (3S)-(E)-1-iodohexa-1,5-dien-3-ol was developed. Ethyl (E)-3-iodoacrylate was converted to racemic (E)-1-iodohexa-1,5-dien-3-ol under flow ...
Cyclopropenone-containing cysteine proteinase inhibitors. Synthesis and enzyme inhibitory activities
Autor:
Kenichi Saito, Hidetoshi Tokuyama, Sota Katayama, Chizuko Takahashi, Masahiko Isaka, Toshiro Sakaki, Narihiko Yoshii, Yasuhiro Morinaka, Yoshikuni Tamao, Ryoichi Ando, Eiichi Nakamura
Publikováno v:
Bioorganic & Medicinal Chemistry. 7:571-579
By focusing on the amphiphilic properties of cyclopropenone (e.g. a good electrophile and a precursor for a stable 2π-aromatic hydroxycyclopropenium cation), a new class of cysteine proteinase inhibitors containing a cyclopropenone moiety was design