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Enhanced antitumor efficacy of an oncolytic adenovirus armed with an EGFR-targeted BiTE using menstrual blood-derived mesenchymal stem cells as carriers.

Autor: Barlabé P; Virotherapy and Gene therapy Group, Oncobell and ProCure Programs, IDIBELL-Instituto Catalan d'Oncología, l'Hospitalet de Llobregat, Barcelona, Spain., Sostoa J; Virotherapy and Gene therapy Group, Oncobell and ProCure Programs, IDIBELL-Instituto Catalan d'Oncología, l'Hospitalet de Llobregat, Barcelona, Spain., Fajardo CA; Virotherapy and Gene therapy Group, Oncobell and ProCure Programs, IDIBELL-Instituto Catalan d'Oncología, l'Hospitalet de Llobregat, Barcelona, Spain., Alemany R; Virotherapy and Gene therapy Group, Oncobell and ProCure Programs, IDIBELL-Instituto Catalan d'Oncología, l'Hospitalet de Llobregat, Barcelona, Spain., Moreno R; Virotherapy and Gene therapy Group, Oncobell and ProCure Programs, IDIBELL-Instituto Catalan d'Oncología, l'Hospitalet de Llobregat, Barcelona, Spain. rafamoreno@iconcologia.net.

Publikováno v: Cancer gene therapy [Cancer Gene Ther] 2020 May; Vol. 27 (5), pp. 383-388. Date of Electronic Publication: 2019 Jun 17.

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Akademický článek

59P Oncolytic adenovirus-based therapeutics to target or reprogram glioma-associated macrophages

Autor: de Sostoa, J., Marinari, E., Widmer, V., Iwaszkiewicz, J., Zoete, V., Michielin, O., Dutoit, V., Migliorini, D.

Publikováno v: In Annals of Oncology December 2021 32 Supplement 7:S1397-S1397

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Akademický článek

Oncolytic Viruses as a Platform for the Treatment of Malignant Brain Tumors.

Autor: Sostoa J; Brain Tumor and Immune Cell Engineering Laboratory, Faculty of Medicine, University of Geneva, 1205 Geneva, Switzerland.; Translational Research Center in Oncohaematology, Faculty of Medicine, University of Geneva, 1205 Geneva, Switzerland.; Swiss Cancer Center Léman, 1005 Lausanne, Switzerland., Dutoit V; Brain Tumor and Immune Cell Engineering Laboratory, Faculty of Medicine, University of Geneva, 1205 Geneva, Switzerland.; Translational Research Center in Oncohaematology, Faculty of Medicine, University of Geneva, 1205 Geneva, Switzerland.; Swiss Cancer Center Léman, 1005 Lausanne, Switzerland., Migliorini D; Brain Tumor and Immune Cell Engineering Laboratory, Faculty of Medicine, University of Geneva, 1205 Geneva, Switzerland.; Translational Research Center in Oncohaematology, Faculty of Medicine, University of Geneva, 1205 Geneva, Switzerland.; Swiss Cancer Center Léman, 1005 Lausanne, Switzerland.; Department of Oncology, Geneva University Hospital, 1211 Geneva, Switzerland.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2020 Oct 09; Vol. 21 (20). Date of Electronic Publication: 2020 Oct 09.

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Akademický článek

Arming Oncolytic Adenoviruses: Effect of Insertion Site and Splice Acceptor on Transgene Expression and Viral Fitness.

Autor: Farrera-Sal M; ProCure Program, Institut Català d'Oncologia, and Oncobell Program IDIBELL, 08908 L'Hospitalet de Llobregat, Spain.; VCN Biosciences S.L., 08174 Sant Cugat, Spain., de Sostoa J; ProCure Program, Institut Català d'Oncologia, and Oncobell Program IDIBELL, 08908 L'Hospitalet de Llobregat, Spain., Nuñez-Manchón E; Institut d'investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Universitat de Barcelona, 08036 Barcelona, Spain., Moreno R; ProCure Program, Institut Català d'Oncologia, and Oncobell Program IDIBELL, 08908 L'Hospitalet de Llobregat, Spain., Fillat C; Institut d'investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Universitat de Barcelona, 08036 Barcelona, Spain., Bazan-Peregrino M; VCN Biosciences S.L., 08174 Sant Cugat, Spain., Alemany R; ProCure Program, Institut Català d'Oncologia, and Oncobell Program IDIBELL, 08908 L'Hospitalet de Llobregat, Spain.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2020 Jul 21; Vol. 21 (14). Date of Electronic Publication: 2020 Jul 21.

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Identification and Functional Analysis of Ras-Related Associated with Diabetes Gene (rrad) in Edwardsiella piscicida -Resistant Individuals of Japanese Flounder (Paralichthys olivaceus).

Autor: Zhu, Ying¹ (AUTHOR) xinsheng0802@163.com, Yang, Xinsheng¹ (AUTHOR) chaoli@qau.edu.cn, Yang, Yingming^2,3 (AUTHOR) yangym@ysfri.ac.cn, Yan, Xu² (AUTHOR) yanxu0210@mails.qust.edu.cn, Li, Chao¹ (AUTHOR), Chen, Songlin^2,3 (AUTHOR) chensl@ysfri.ac.cn

Publikováno v: International Journal of Molecular Sciences. Oct2024, Vol. 25 Issue 19, p10532. 15p.

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Optimizing Pancreatic Cancer Therapy: The Promise of Immune Stimulatory Oncolytic Viruses.

Autor: Thoidingjam, Shivani¹ (AUTHOR), Bhatnagar, Aseem Rai¹ (AUTHOR), Sriramulu, Sushmitha¹ (AUTHOR), Siddiqui, Farzan^1,2,3 (AUTHOR), Nyati, Shyam^1,2,4 (AUTHOR) snyati1@hfhs.org

Publikováno v: International Journal of Molecular Sciences. Sep2024, Vol. 25 Issue 18, p9912. 20p.

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Targeting the tumor stroma with an oncolytic adenovirus secreting a fibroblast activation protein-targeted bispecific T-cell engager.

Autor: de Sostoa J; ProCure Program, IDIBELL-Institut Català d'Oncologia, l'Hospitalet de Llobregat, El Prat de Llobregat, Spain., Fajardo CA; ProCure Program, IDIBELL-Institut Català d'Oncologia, l'Hospitalet de Llobregat, El Prat de Llobregat, Spain., Moreno R; ProCure Program, IDIBELL-Institut Català d'Oncologia, l'Hospitalet de Llobregat, El Prat de Llobregat, Spain., Ramos MD; ProCure Program, IDIBELL-Institut Català d'Oncologia, l'Hospitalet de Llobregat, El Prat de Llobregat, Spain., Farrera-Sal M; ProCure Program, IDIBELL-Institut Català d'Oncologia, l'Hospitalet de Llobregat, El Prat de Llobregat, Spain.; VCN Biosciences S.L., Grifols Corporate Offices, Sant Cugat del Vallès, Spain., Alemany R; ProCure Program, IDIBELL-Institut Català d'Oncologia, l'Hospitalet de Llobregat, El Prat de Llobregat, Spain. ralemany@iconcologia.net.

Publikováno v: Journal for immunotherapy of cancer [J Immunother Cancer] 2019 Jan 25; Vol. 7 (1), pp. 19. Date of Electronic Publication: 2019 Jan 25.

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IGF1R signaling induces epithelial-mesenchymal plasticity via ITGAV in cutaneous carcinoma.

Autor: Lopez-Cerda, Marta¹ (AUTHOR) mlopezc@idibell.cat, Lorenzo-Sanz, Laura¹ (AUTHOR), da Silva-Diz, Victoria^1,2 (AUTHOR), Llop, Sandra³ (AUTHOR), Penin, Rosa M.⁴ (AUTHOR), Bermejo, Josep Oriol⁵ (AUTHOR), de Goeij-de Haas, Richard⁶ (AUTHOR), Piersma, Sander R.⁶ (AUTHOR), Pham, Thang V.⁶ (AUTHOR), Jimenez, Connie R.⁶ (AUTHOR), Martin-Liberal, Juan³ (AUTHOR) jmartinliberal@iconcologia.net, Muñoz, Purificación¹ (AUTHOR) p.munoz@idibell.cat

Publikováno v: Journal of Experimental & Clinical Cancer Research (17569966). 7/29/2024, Vol. 43 Issue 1, p1-21. 21p.

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Bioengineered Mesenchymal Stem/Stromal Cells in Anti-Cancer Therapy: Current Trends and Future Prospects.

Autor: Gil-Chinchilla, Jesús I.¹ (AUTHOR) jesusisaias.gil@um.es, Zapata, Agustín G.² (AUTHOR) zapata@bio.ucm.es, Moraleda, Jose M.^1,3 (AUTHOR) jmoraled@um.es, García-Bernal, David^1,4 (AUTHOR) jmoraled@um.es

Publikováno v: Biomolecules (2218-273X). Jul2024, Vol. 14 Issue 7, p734. 25p.

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