Author Correction: Cancer-associated Histone H3 N-terminal arginine mutations disrupt PRC2 activity and impair differentiation.

Autor: Nacev BA; Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, 15213, USA. ben46@pitt.edu.; Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, 15213, USA. ben46@pitt.edu.; UPMC Hillman Cancer Center, Pittsburgh, PA, 15213, USA. ben46@pitt.edu., Dabas Y; Laboratory of Chromatin Biology and Epigenetics, The Rockefeller University, New York, NY, 10065, USA., Paul MR; Bioinformatics Resource Center, The Rockefeller University, New York, NY, 10065, USA., Pacheco C; Laboratory of Chromatin Biology and Epigenetics, The Rockefeller University, New York, NY, 10065, USA., Mitchener M; Department of Chemistry, Princeton University, Princeton, NJ, 08544, USA., Perez Y; Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Fang Y; Laboratory of Chromatin Biology and Epigenetics, The Rockefeller University, New York, NY, 10065, USA.; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Soshnev AA; Laboratory of Chromatin Biology and Epigenetics, The Rockefeller University, New York, NY, 10065, USA.; Department of Neuroscience, Developmental and Regenerative Biology, The University of Texas at San Antonio, San Antonio, TX, 78249, USA., Barrows D; Bioinformatics Resource Center, The Rockefeller University, New York, NY, 10065, USA., Carroll T; Bioinformatics Resource Center, The Rockefeller University, New York, NY, 10065, USA., Socci ND; Bioinformatics Core, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., St Jean SC; Laboratory of Comparative Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Tiwari S; Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, 15213, USA.; UPMC Hillman Cancer Center, Pittsburgh, PA, 15213, USA., Gruss MJ; Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, 15213, USA.; UPMC Hillman Cancer Center, Pittsburgh, PA, 15213, USA., Monette S; Laboratory of Comparative Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Tap WD; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Garcia BA; Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, MO, 63110, USA., Muir T; Department of Chemistry, Princeton University, Princeton, NJ, 08544, USA., Allis CD; Laboratory of Chromatin Biology and Epigenetics, The Rockefeller University, New York, NY, 10065, USA.

Publikováno v: Nature communications [Nat Commun] 2024 Oct 22; Vol. 15 (1), pp. 9103. Date of Electronic Publication: 2024 Oct 22.

Cancer-associated Histone H3 N-terminal arginine mutations disrupt PRC2 activity and impair differentiation.

Autor: Nacev BA; Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, 15213, USA. ben46@pitt.edu.; Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, 15213, USA. ben46@pitt.edu.; UPMC Hillman Cancer Center, Pittsburgh, PA, 15213, USA. ben46@pitt.edu., Dabas Y; Laboratory of Chromatin Biology and Epigenetics, The Rockefeller University, New York, NY, 10065, USA., Paul MR; Bioinformatics Resource Center, The Rockefeller University, New York, NY, 10065, USA., Pacheco C; Laboratory of Chromatin Biology and Epigenetics, The Rockefeller University, New York, NY, 10065, USA., Mitchener M; Department of Chemistry, Princeton University, Princeton, NJ, 08544, USA., Perez Y; Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Fang Y; Laboratory of Chromatin Biology and Epigenetics, The Rockefeller University, New York, NY, 10065, USA.; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Soshnev AA; Laboratory of Chromatin Biology and Epigenetics, The Rockefeller University, New York, NY, 10065, USA.; Department of Neuroscience, Developmental and Regenerative Biology, The University of Texas at San Antonio, San Antonio, TX, 78249, USA., Barrows D; Bioinformatics Resource Center, The Rockefeller University, New York, NY, 10065, USA., Carroll T; Bioinformatics Resource Center, The Rockefeller University, New York, NY, 10065, USA., Socci ND; Bioinformatics Core, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., St Jean SC; Laboratory of Comparative Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Tiwari S; Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, 15213, USA.; UPMC Hillman Cancer Center, Pittsburgh, PA, 15213, USA., Gruss MJ; Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, 15213, USA.; UPMC Hillman Cancer Center, Pittsburgh, PA, 15213, USA., Monette S; Laboratory of Comparative Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Tap WD; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Garcia BA; Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, MO, 63110, USA., Muir T; Department of Chemistry, Princeton University, Princeton, NJ, 08544, USA., Allis CD; Laboratory of Chromatin Biology and Epigenetics, The Rockefeller University, New York, NY, 10065, USA.

Publikováno v: Nature communications [Nat Commun] 2024 Jun 17; Vol. 15 (1), pp. 5155. Date of Electronic Publication: 2024 Jun 17.

Altered chromatin occupancy of patient-associated H4 mutants misregulate neuronal differentiation.

Autor: Feng L; The Rockefeller University, Laboratory of Chromatin Biology and Epigenetics, New York, NY., Barrows D; The Rockefeller University, Bioinformatics Resource Center, New York, NY., Zhong L; Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine, Weill Cornell Medicine, New York, NY., Mätlik K; The Rockefeller University, Laboratory of Developmental Neurobiology, New York, NY., Porter EG; Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, MO., Djomo AM; The Rockefeller University, Laboratory of Chromatin Biology and Epigenetics, New York, NY., Yau I; The Rockefeller University, Laboratory of Chromatin Biology and Epigenetics, New York, NY.; Hunter College of the City University of New York, Yalow Honors Scholar Program, New York, NY., Soshnev AA; The Rockefeller University, Laboratory of Chromatin Biology and Epigenetics, New York, NY.; Department of Neuroscience, Developmental and Regenerative Biology, The University of Texas at San Antonio, San Antonio, TX., Carroll TS; The Rockefeller University, Bioinformatics Resource Center, New York, NY., Wen D; Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine, Weill Cornell Medicine, New York, NY., Hatten ME; The Rockefeller University, Laboratory of Developmental Neurobiology, New York, NY., Garcia BA; Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, MO., Allis CD; The Rockefeller University, Laboratory of Chromatin Biology and Epigenetics, New York, NY.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Sep 29. Date of Electronic Publication: 2023 Sep 29.

A Molecular Switch between Mammalian MLL Complexes Dictates Response to Menin-MLL Inhibition.

Autor: Soto-Feliciano YM; Laboratory of Chromatin Biology and Epigenetics, The Rockefeller University, New York, New York., Sánchez-Rivera FJ; Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, New York., Perner F; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Division of Hematology/Oncology, Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts.; Internal Medicine C, Greifswald University Medical Center, Greifswald, Germany., Barrows DW; Laboratory of Chromatin Biology and Epigenetics, The Rockefeller University, New York, New York.; Bioinformatics Resource Center, The Rockefeller University, New York, New York., Kastenhuber ER; Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, New York., Ho YJ; Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, New York., Carroll T; Bioinformatics Resource Center, The Rockefeller University, New York, New York., Xiong Y; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Division of Hematology/Oncology, Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts., Anand D; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Internal Medicine C, Greifswald University Medical Center, Greifswald, Germany., Soshnev AA; Laboratory of Chromatin Biology and Epigenetics, The Rockefeller University, New York, New York., Gates L; Laboratory of Chromatin Biology and Epigenetics, The Rockefeller University, New York, New York., Beytagh MC; Laboratory of Chromatin Biology and Epigenetics, The Rockefeller University, New York, New York., Cheon D; Laboratory of Chromatin Biology and Epigenetics, The Rockefeller University, New York, New York., Gu S; Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Harvard School of Public Health, Boston, Massachusetts.; Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, Massachusetts., Liu XS; Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Harvard School of Public Health, Boston, Massachusetts.; Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, Massachusetts., Krivtsov AV; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Division of Hematology/Oncology, Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts., Meneses M; Antitumor Assessment Core Facility, Memorial Sloan Kettering Cancer Center, New York, New York., de Stanchina E; Antitumor Assessment Core Facility, Memorial Sloan Kettering Cancer Center, New York, New York., Stone RM; Leukemia Division, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Armstrong SA; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Division of Hematology/Oncology, Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts., Lowe SW; Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, New York., Allis CD; Laboratory of Chromatin Biology and Epigenetics, The Rockefeller University, New York, New York.

Publikováno v: Cancer discovery [Cancer Discov] 2023 Jan 09; Vol. 13 (1), pp. 146-169.

Histone H1 loss drives lymphoma by disrupting 3D chromatin architecture.

Autor: Yusufova N; Division of Hematology and Medical Oncology, Sanford I. Weill Department of Medicine, Weill Cornell Medicine, New York, NY, USA.; Cell and Molecular Biology Graduate Program, Weill Cornell Medicine, New York, NY, USA., Kloetgen A; Department of Pathology, NYU School of Medicine, New York, NY, USA.; Department of Computational Biology of Infection Research, Helmholtz Centre for Infection Research, Braunschweig, Germany., Teater M; Division of Hematology and Medical Oncology, Sanford I. Weill Department of Medicine, Weill Cornell Medicine, New York, NY, USA., Osunsade A; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Tri-Institutional PhD Program in Chemical Biology, New York, NY, USA., Camarillo JM; Department of Chemistry, Northwestern University, Evanston, IL, USA.; Department of Molecular Biosciences, Northwestern University, Evanston, IL, USA.; Proteomics Center of Excellence, Northwestern University, Evanston, IL, USA., Chin CR; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, USA.; Tri-Institutional PhD Program in Computational Biomedicine, New York, NY, USA., Doane AS; Tri-Institutional PhD Program in Computational Biomedicine, New York, NY, USA.; Institute for Computational Biomedicine, Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, USA., Venters BJ; EpiCypher, Durham, NC, USA., Portillo-Ledesma S; Department of Chemistry, New York University, New York, NY, USA., Conway J; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA., Phillip JM; Division of Hematology and Medical Oncology, Sanford I. Weill Department of Medicine, Weill Cornell Medicine, New York, NY, USA., Elemento O; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, USA., Scott DW; Centre for Lymphoid Cancer, BC Cancer, Vancouver, British Columbia, Canada., Béguelin W; Division of Hematology and Medical Oncology, Sanford I. Weill Department of Medicine, Weill Cornell Medicine, New York, NY, USA., Licht JD; University of Florida Health Cancer Center, The University of Florida Cancer and Genetics Research Complex, Gainesville, FL, USA., Kelleher NL; Department of Chemistry, Northwestern University, Evanston, IL, USA.; Department of Molecular Biosciences, Northwestern University, Evanston, IL, USA.; Proteomics Center of Excellence, Northwestern University, Evanston, IL, USA., Staudt LM; Lymphoid Malignancies Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Skoultchi AI; Department of Cell Biology, Albert Einstein College of Medicine, New York, NY, USA., Keogh MC; EpiCypher, Durham, NC, USA., Apostolou E; Sanford I. Weill Department of Medicine, Weill Cornell Medicine, New York, NY, USA.; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA., Mason CE; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, USA.; The WorldQuant Initiative for Quantitative Prediction, Weill Cornell Medicine, New York, NY, USA.; The Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY, USA., Imielinski M; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA., Schlick T; Department of Chemistry, New York University, New York, NY, USA.; Courant Institute of Mathematical Sciences, New York University, New York, NY, USA.; New York University-East China Normal University Center for Computational Chemistry at New York University Shanghai, Shanghai, China., David Y; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Tri-Institutional PhD Program in Chemical Biology, New York, NY, USA., Tsirigos A; Department of Pathology, NYU School of Medicine, New York, NY, USA.; Institute for Computational Medicine, NYU School of Medicine, New York, NY, USA., Allis CD; Laboratory of Chromatin Biology and Epigenetics, The Rockefeller University, New York, NY, USA., Soshnev AA; Laboratory of Chromatin Biology and Epigenetics, The Rockefeller University, New York, NY, USA. asoshnev@rockefeller.edu., Cesarman E; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA. ecesarm@med.cornell.edu., Melnick AM; Division of Hematology and Medical Oncology, Sanford I. Weill Department of Medicine, Weill Cornell Medicine, New York, NY, USA. amm2014@med.cornell.edu.

Publikováno v: Nature [Nature] 2021 Jan; Vol. 589 (7841), pp. 299-305. Date of Electronic Publication: 2020 Dec 09.