Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Soshi Seike"'
Publikováno v:
Toxins, Vol 15, Iss 12, p 695 (2023)
Clostridium perfringens iota-toxin is composed of two separate proteins: a binding protein (Ib) that recognizes a host cell receptor and promotes the cellular uptake of a catalytic protein and (Ia) possessing ADP-ribosyltransferase activity that indu
Externí odkaz:
https://doaj.org/article/a562d8e7695d43949a6779814f64af3e
Autor:
Mitsunobu Ueda, Hidetomo Kobayashi, Soshi Seike, Eizo Takahashi, Keinosuke Okamoto, Hiroyasu Yamanaka
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Aeromonas sobria is a Gram-negative pathogen that causes food-borne illness. In immunocompromised patients and the elderly, A. sobria opportunistically leads to severe extraintestinal diseases including sepsis, peritonitis, and meningitis. If A. sobr
Externí odkaz:
https://doaj.org/article/2ef6c863728b4c71bc8c24ecbc85158e
Autor:
Soshi Seike, Hidetomo Kobayashi, Mitsunobu Ueda, Eizo Takahashi, Keinosuke Okamoto, Hiroyasu Yamanaka
Publikováno v:
Frontiers in Microbiology, Vol 11 (2021)
Aeromonas spp. are Gram-negative rod-shaped bacteria ubiquitously distributed in diverse water sources. Several Aeromonas spp. are known as human and fish pathogens. Recently, attention has been focused on the relationship between bacterial biofilm f
Externí odkaz:
https://doaj.org/article/3b1e1f500ed549beb596ff4da2e06065
Autor:
Teruhisa Takagishi, Masaya Takehara, Soshi Seike, Kazuaki Miyamoto, Keiko Kobayashi, Masahiro Nagahama
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Clostridium perfringens α-toxin induces hemolysis of erythrocytes from various species, but it has not been elucidated whether the toxin affects erythropoiesis. In this study, we treated bone marrow cells (BMCs) from mice with purified α-t
Externí odkaz:
https://doaj.org/article/e6573dc0560148879093d39d2ad95eea
Autor:
Hidetomo Kobayashi, Soshi Seike, Masafumi Yamaguchi, Mitsunobu Ueda, Eizo Takahashi, Keinosuke Okamoto, Hiroyasu Yamanaka
Publikováno v:
PLoS ONE, Vol 14, Iss 8, p e0221344 (2019)
Aeromonas sobria is a pathogen causing food-borne illness. In immunocompromised patients and the elderly, A. sobria can leave the intestinal tract, and this opportunistically leads to severe extraintestinal diseases including sepsis, peritonitis, and
Externí odkaz:
https://doaj.org/article/7c0613c31d2046c0b0bfb73d913da0ab
Publikováno v:
Toxins, Vol 12, Iss 5, p 286 (2020)
Epsilon-toxin produced by Clostridium perfringens significantly contributes to the pathogeneses of enterotoxemia in ruminants and multiple sclerosis in humans. Epsilon-toxin forms a heptameric oligomer in the host cell membrane, promoting cell disrup
Externí odkaz:
https://doaj.org/article/c1021a11c73440728f3ff0e0355b49c8
Autor:
Hidetomo Kobayashi, Tadamune Otsubo, Fumiteru Teraoka, Kiyoshi Ikeda, Soshi Seike, Eizo Takahashi, Keinosuke Okamoto, Toru Yoshida, Hideaki Tsuge, Hiroyasu Yamanaka
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186392 (2017)
Aeromonas sobria serine protease (ASP) is an extracellular serine protease secreted by the organism. Here, we identified the amino acid residue of ASP that contributes to substrate specificity by using both synthetic peptides and biological protein c
Externí odkaz:
https://doaj.org/article/e2a5dce98545411babad40f6d2bf5466
Publikováno v:
Toxins, Vol 11, Iss 4, p 232 (2019)
Clostridium perfringens strains B and C cause fatal intestinal diseases in animals. The secreted pore-forming toxin delta-toxin is one of the virulence factors of the strains, but the mechanism of intestinal pathogenesis is unclear. Here, we investig
Externí odkaz:
https://doaj.org/article/907d4ed3f65e4034b8b215eff8b65d0a
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0147957 (2016)
Clostridium perfringens delta-toxin is a β-pore-forming toxin and a putative pathogenic agent of C. perfringens types B and C. However, the mechanism of cytotoxicity of delta-toxin remains unclear. Here, we investigated the mechanisms of cell death
Externí odkaz:
https://doaj.org/article/4e816a827aa443e081e36e474bcff449
Autor:
Masaya Takehara, Teruhisa Takagishi, Soshi Seike, Masataka Oda, Yoshihiko Sakaguchi, Junzo Hisatsune, Sadayuki Ochi, Keiko Kobayashi, Masahiro Nagahama
Publikováno v:
Toxins, Vol 9, Iss 8, p 247 (2017)
Clostridium perfringens iota-toxin and Clostridium botulinum C2 toxin are composed of two non-linked proteins, one being the enzymatic component and the other being the binding/translocation component. These latter components recognize specific recep
Externí odkaz:
https://doaj.org/article/1b957cc57b23409b90f282f267ddbe91