Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Soroush T Sarvestani"'
Autor:
Hanne Dubois, Frederic Sorgeloos, Soroush T Sarvestani, Liesbet Martens, Yvan Saeys, Jason M Mackenzie, Mohamed Lamkanfi, Geert van Loo, Ian Goodfellow, Andy Wullaert
Publikováno v:
PLoS Pathogens, Vol 15, Iss 4, p e1007709 (2019)
Norovirus infection is the leading cause of food-borne gastroenteritis worldwide, being responsible for over 200,000 deaths annually. Studies with murine norovirus (MNV) showed that protective STAT1 signaling controls viral replication and pathogenes
Externí odkaz:
https://doaj.org/article/a5e5350e08ed4b97b673e9f53edd4c1b
Autor:
H. James Stunden, Bryan R.G. Williams, Kim A. Lennox, Mark A. Behlke, Soroush T. Sarvestani, Michael P. Gantier, Eicke Latz, Michelle D. Tate, Samuel C. Forster, Claire E. McCoy, Jonathan Ferrand
Publikováno v:
Nucleic Acids Research
Nucleic acids symposium series 43(2), 1177-1188 (2014). doi:10.1093/nar/gku1343
Nucleic acids symposium series 43(2), 1177-1188 (2014). doi:10.1093/nar/gku1343
Anti-microRNA (miRNA) oligonucleotides (AMOs) with 2'-O-Methyl (2'OMe) residues are commonly used to study miRNA function and can achieve high potency, with low cytotoxicity. Not withstanding this, we demonstrate the sequence-dependent capacity of 2'
Autor:
Julie L. McAuley, Soroush T Sarvestani
Publikováno v:
Antiviral research. 148
The innate immune system provides the host with both a dynamic barrier to prevent infection and a means to which rapid anti-microbial responses can be mounted. The inflammasome pathway is a critical host early response mechanism that enables detectio
Autor:
Ben T Cotton, Kim Y. Green, Stanislav V. Sosnovtsev, Jennifer L. Hyde, Jason M. Mackenzie, Soroush T Sarvestani, Peter A. White
Publikováno v:
Journal of Virology. 91
Norovirus (NoV) infections are a significant health burden to society, yet the lack of reliable tissue culture systems has hampered the development of appropriate antiviral therapies. Here we show that the NoV NS3 protein, derived from murine NoV (MN
Autor:
Afsar U. Ahmed, Soroush T. Sarvestani, Gregory Hannigan, Michael P. Gantier, Bryan R.G. Williams
Publikováno v:
Journal of Biological Chemistry. 289:27776-27793
Integrin-linked kinase (ILK) is a ubiquitously expressed and highly conserved serine-threonine protein kinase that regulates cellular responses to a wide variety of extracellular stimuli. ILK is involved in cell-matrix interactions, cytoskeletal orga
Autor:
Alistair Miller, Weisan Chen, Matthias John, Ashley M. Jacobi, Jessica M Moffat, Bryan R.G. Williams, Soroush T. Sarvestani, Justine D. Mintern, Michael P. Gantier, Simone A. Beckham, Meredith O'Keeffe, Mark A. Behlke, Michelle D. Tate, Claire E. McCoy
Publikováno v:
Journal of Virology. 88:799-810
RNA-specific adenosine deaminase (ADAR)-mediated adenosine-to-inosine (A-to-I) editing is a critical arm of the antiviral response. However, mechanistic insights into how A-to-I RNA editing affects viral infection are lacking. We posited that inosine
Autor:
Liesbet Martens, Mohamed Lamkanfi, Andy Wullaert, Soroush T Sarvestani, Jason M. Mackenzie, Frédéric Sorgeloos, Ian Goodfellow, Yvan Saeys, Geert van Loo, Hanne Dubois
Publikováno v:
PLoS Pathogens, Vol 15, Iss 4, p e1007709 (2019)
PLOS PATHOGENS
PLoS Pathogens
PLOS PATHOGENS
PLoS Pathogens
Norovirus infection is the leading cause of food-borne gastroenteritis worldwide, being responsible for over 200,000 deaths annually. Studies with murine norovirus (MNV) showed that protective STAT1 signaling controls viral replication and pathogenes
Publikováno v:
Journal of interferoncytokine research : the official journal of the International Society for Interferon and Cytokine Research. 36(4)
Noroviruses (NoVs) belong to the Caliciviridae family of viruses and are responsible for causing the majority of gastroenteritis outbreaks worldwide. In the past decade, research on NoV biology has intensified because of the discovery of murine NoV a
Autor:
Michael P. Gantier, Mark A. Behlke, Bryan R.G. Williams, Sinéad C. Corr, Die Wang, Yuan Hang Yang, Dakang Xu, Maria Kaparakis-Liaskos, H. James Stunden, Claire E. McCoy, Soroush T. Sarvestani, Eric F Morand
Publikováno v:
Nucleic Acids Research
Fine-tuning of inflammatory responses by microRNAs (miRNAs) is complex, as they can both enhance and repress expression of pro-inflammatory mediators. In this study, we investigate inflammatory responses following global miRNA depletion, to better de
Publikováno v:
Cytokine. 70:67-68
Anti-microRNA (miRNA) oligonucleotides (AMOs) are commonly used to study miRNA function and present clear therapeutic potential. 2′-O-methyl (2′Ome) modified AMOs are among the most popular AMOs and can be modified to achieve high potency, high s