Zobrazeno 1 - 10
of 269
pro vyhledávání: '"Sormanni, Pietro"'
Autor:
Lawrence, Elsa, El-Shazly, Adham, Seal, Srijit, Joshi, Chaitanya K, Liò, Pietro, Singh, Shantanu, Bender, Andreas, Sormanni, Pietro, Greenig, Matthew
Modern life sciences research is increasingly relying on artificial intelligence approaches to model biological systems, primarily centered around the use of machine learning (ML) models. Although ML is undeniably useful for identifying patterns in l
Externí odkaz:
http://arxiv.org/abs/2403.04106
Autor:
Ucar, Talip, Ramon, Aubin, Oglic, Dino, Croasdale-Wood, Rebecca, Diethe, Tom, Sormanni, Pietro
We investigate the potential of patent data for improving the antibody humanness prediction using a multi-stage, multi-loss training process. Humanness serves as a proxy for the immunogenic response to antibody therapeutics, one of the major causes o
Externí odkaz:
http://arxiv.org/abs/2401.14442
Score-based generative models (SGMs) have proven to be powerful tools for designing new proteins. Designing proteins that bind a pre-specified target is highly relevant to a range of medical and industrial applications. Despite the flurry of new SGMs
Externí odkaz:
http://arxiv.org/abs/2310.07051
Autor:
Pang, Kuin Tian, Yang, Yuan Sheng, Zhang, Wei, Ho, Ying Swan, Sormanni, Pietro, Michaels, Thomas C.T., Walsh, Ian, Chia, Sean
Publikováno v:
In Biotechnology Advances October 2023 67
Akademický článek
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Antibodies are a critical part of the immune system, having the function of directly neutralising or tagging undesirable objects (the antigens) for future destruction. Being able to predict which amino acids belong to the paratope, the region on the
Externí odkaz:
http://arxiv.org/abs/1806.04398
Akademický článek
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Autor:
Aprile, Francesco A., Sormanni, Pietro, Podpolny, Marina, Chhangur, Shianne, Needham, Lisa-Maria, Ruggeri, Francesco S., Perni, Michele, Limbocker, Ryan, Heller, Gabriella T., Sneideris, Tomas, Scheidt, Tom, Mannini, Benedetta, Habchi, Johnny, Lee, Steven F., Salinas, Patricia C., Knowles, Tuomas P. J., Dobson, Christopher M., Vendruscolo, Michele
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2020 Jun . 117(24), 13509-13518.
Externí odkaz:
https://www.jstor.org/stable/26968501
Autor:
Vecchi, Giulia, Sormanni, Pietro, Mannini, Benedetta, Vandelli, Andrea, Tartaglia, Gian Gaetano, Dobson, Christopher M., Hartl, F. Ulrich, Vendruscolo, Michele
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2020 Jan . 117(2), 1015-1020.
Externí odkaz:
https://www.jstor.org/stable/26896974
Autor:
Lindstedt, Philip R., Aprile, Francesco A., Sormanni, Pietro, Rakoto, Robertinah, Dobson, Christopher M., Bernardes, Gonçalo J.L., Vendruscolo, Michele
Publikováno v:
In Cell Chemical Biology 21 January 2021 28(1):70-77