Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Sorin Tanase-Nicola"'
Publikováno v:
Communications Physics, Vol 5, Iss 1, Pp 1-12 (2022)
The total reaction flux catalysed by immobilized enzymes depends on their spatial arrangement. The problem of optimizing the arrangement to maximize the reaction flux is analogous to a portfolio optimization problem, which is solved here to obtain th
Externí odkaz:
https://doaj.org/article/c6807103d4244035a66f31905a7580f9
Publikováno v:
Biophysical Journal. 94(9):3413-3423
We present a detailed analysis, based on the Forward Flux Sampling (FFS) simulation method, of the switching dynamics and stability of two models of genetic toggle switches, consisting of two mutually-repressing genes encoding transcription factors (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f5fc3a52345aa9fa2cbb72c6455dbf9
Publikováno v:
Journal of Statistical Physics
Journal of Statistical Physics, Springer Verlag, 2006, 122 (4), pp.557--595
Journal of Statistical Physics, Springer Verlag, 2006, 122 (4), pp.557--595
Hamilton's equations with noise and friction possess a hidden supersymmetry, valid for time-independent as well as periodically time-dependent systems. It is used to derive topological properties of critical points and periodic trajectories in an ele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12cf31cfba1b55dd09cb78b4efe942b4
https://doi.org/10.1007/s10955-005-8059-x
https://doi.org/10.1007/s10955-005-8059-x
Autor:
Sorin Tanase-Nicola, Jorge Kurchan
Publikováno v:
Journal of Statistical Physics
Journal of Statistical Physics, Springer Verlag, 2004, 116 (5-6), pp.1201--1245
Journal of Statistical Physics, Springer Verlag, 2004, 116 (5-6), pp.1201--1245
Langevin/Fokker-Planck processes can be immersed in a larger frame by adding fictitious fermion variables. The ( super) symmetry of this larger structure has been used to derive Morse theory in an elegant way. The original physical diffusive motion i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56226013e94b2222f3c394ea5ea025fd
https://doi.org/10.1023/b:joss.0000041739.53068.6a
https://doi.org/10.1023/b:joss.0000041739.53068.6a
Autor:
Sorin Tanase-Nicola, David K. Lubensky
Publikováno v:
Physical Review E. 86
In equilibrium systems with short-ranged interactions, the relative stability of different thermodynamic states generally does not depend on system size (as long as this size is larger than the interaction range). Here, we use a large deviations appr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfa62f6d964f71a3621567320ac0d467
https://doi.org/10.1103/physreve.86.040103
https://doi.org/10.1103/physreve.86.040103
Autor:
Sorin Tanase-Nicola, Ilya Nemenman
Phenotypic evolution implies sequential rise in frequency of new genomic sequences. The speed of the rise depends, in part, on the relative fitness (selection coefficient) of the mutant versus the ancestor. Using a simple population dynamics model, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7970e16dea0b2d3e7ad00666e6188aad
Publikováno v:
Journal of theoretical biology. 272(1)
Having multiple peaks within fitness landscapes critically affects the course of evolution, but whether their presence imposes specific requirements at the level of genetic interactions remains unestablished. Here we show that to exhibit multiple fit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a37482486ff651d72c624c44ce2ae303
https://pubmed.ncbi.nlm.nih.gov/21167837
https://pubmed.ncbi.nlm.nih.gov/21167837
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 107(6)
Multisite covalent modification of proteins is omnipresent in eukaryotic cells. A well-known example is the mitogen-activated protein kinase (MAPK) cascade where, in each layer of the cascade, a protein is phosphorylated at two sites. It has long bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaa28aedb9e8f1a51161cc66a5e696b9
https://pubmed.ncbi.nlm.nih.gov/20133748
https://pubmed.ncbi.nlm.nih.gov/20133748
We consider a fixed size population that undergoes an evolutionary adaptation in the weak mutuation rate limit, which we model as a biased Langevin process in the genotype space. We show analytically and numerically that, if the fitness landscape has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a891b84909d7218cf00bba5c1883d731
Publikováno v:
Radiation Protection Dosimetry. 85:183-185
The fading of the thermoluminescent phosphors used as dosemeters is of great importance when it comes to calibrating a dosimetric system. The results of a series of experiments performed in order to determine some fading characteristics of TLD-100 (H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70b425b213e8b694be779f8506f4763d
https://doi.org/10.1093/oxfordjournals.rpd.a032831
https://doi.org/10.1093/oxfordjournals.rpd.a032831