Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Soren Buus"'
Autor:
Loulieta Nazerai, Shona Caroline Willis, Patricio Yankilevich, Luca Di Leo, Francesca Maria Bosisio, Alex Frias, Corine Bertolotto, Jacob Nersting, Maria Thastrup, Soren Buus, Allan Randrup Thomsen, Morten Nielsen, Kristoffer Staal Rohrberg, Kjeld Schmiegelow, Daniela De Zio
Publikováno v:
OncoImmunology, Vol 12, Iss 1 (2023)
ABSTRACTImmune-checkpoint inhibitors (ICI) are highly effective in reinvigorating T cells to attack cancer. Nevertheless, a large subset of patients fails to benefit from ICI, partly due to lack of the cancer neoepitopes necessary to trigger an immun
Externí odkaz:
https://doaj.org/article/4dfe4b677ec94c7b9323ef328b78f448
Autor:
Sandra Eltschkner, Samantha Mellinger, Soren Buus, Morten Nielsen, Kajsa M. Paulsson, Karin Lindkvist-Petersson, Helena Westerdahl
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Long-distance migratory animals such as birds and bats have evolved to withstand selection imposed by pathogens across the globe, and pathogen richness is known to be particularly high in tropical regions. Immune genes, so-called Major Histocompatibi
Externí odkaz:
https://doaj.org/article/455a33948917410fbe59f17dd030ee1f
Autor:
Dorthe Maria Vittrup, Anne Cathrine Lund Laursen, Michelle Malon, Jesper Kiehn Soerensen, Jakob Hjort, Soren Buus, Jannet Svensson, Lone Graff Stensballe
Publikováno v:
Trials, Vol 21, Iss 1, Pp 1-8 (2020)
Abstract Background Measles is a highly contagious and serious infection. Before the introduction of vaccination, measles caused yearly epidemics putting vulnerable children at risk of brain damage and death. Despite safe and cost-effective vaccines,
Externí odkaz:
https://doaj.org/article/79e969b33f5549359fa951439eb2e690
Autor:
Timothy Connelley, Annalisa Nicastri, Tara Sheldrake, Christina Vrettou, Andressa Fisch, Birkir Reynisson, Soren Buus, Adrian Hill, Ivan Morrison, Morten Nielsen, Nicola Ternette
Publikováno v:
Vaccines, Vol 10, Iss 11, p 1907 (2022)
The apicomplexan parasite Theileria parva is the causative agent of East Coast fever, usually a fatal disease for cattle, which is prevalent in large areas of eastern, central, and southern Africa. Protective immunity against T. parva is mediated by
Externí odkaz:
https://doaj.org/article/dadd14e014b049a7a67f0ffe0c8f02a6
Autor:
Anette Stryhn, Michael Kongsgaard, Michael Rasmussen, Mikkel Nors Harndahl, Thomas Østerbye, Maria Rosaria Bassi, Søren Thybo, Mette Gabriel, Morten Bagge Hansen, Morten Nielsen, Jan Pravsgaard Christensen, Allan Randrup Thomsen, Soren Buus
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Examining CD8+ and CD4+ T cell responses after primary Yellow Fever vaccination in a cohort of 210 volunteers, we have identified and tetramer-validated 92 CD8+ and 50 CD4+ T cell epitopes, many inducing strong and prevalent (i.e., immunodominant) T
Externí odkaz:
https://doaj.org/article/b8fb5297c13149d797fdd9685dc406b6
Autor:
Rebecca Pavlos, Elizabeth J. McKinnon, David A. Ostrov, Bjoern Peters, Soren Buus, David Koelle, Abha Chopra, Ryan Schutte, Craig Rive, Alec Redwood, Susana Restrepo, Austin Bracey, Thomas Kaever, Paisley Myers, Ellen Speers, Stacy A. Malaker, Jeffrey Shabanowitz, Yuan Jing, Silvana Gaudieri, Donald F. Hunt, Mary Carrington, David W. Haas, Simon Mallal, Elizabeth J. Phillips
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Genes of the human leukocyte antigen (HLA) system encode cell-surface proteins involved in regulation of immune responses, and the way drugs interact with the HLA peptide binding groove is important in the immunopathogenesis of T-cell mediat
Externí odkaz:
https://doaj.org/article/713379e67e8e4c309dc4c182e4231712
Autor:
Michael Kongsgaard, Maria R. Bassi, Michael Rasmussen, Karsten Skjødt, Søren Thybo, Mette Gabriel, Morten Bagge Hansen, Jan Pravsgaard Christensen, Allan Randrup Thomsen, Soren Buus, Anette Stryhn
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract Outbreaks of Yellow Fever occur regularly in endemic areas of Africa and South America frequently leading to mass vaccination campaigns straining the availability of the attenuated Yellow Fever vaccine, YF-17D. The WHO has recently decided t
Externí odkaz:
https://doaj.org/article/6138471ef15e4c36a3b886477a297b6b
Autor:
Imir G Metushi, Amanda Wriston, Priyanka Banerjee, Bjoern Oliver Gohlke, A Michelle English, Andrew Lucas, Carrie Moore, John Sidney, Soren Buus, David A Ostrov, Simon Mallal, Elizabeth Phillips, Jeffrey Shabanowitz, Donald F Hunt, Robert Preissner, Bjoern Peters
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0124878 (2015)
Immune mediated adverse drug reactions (IM-ADRs) remain a significant source of patient morbidity that have more recently been shown to be associated with specific class I and/or II human leukocyte antigen (HLA) alleles. Abacavir-induced hypersensiti
Externí odkaz:
https://doaj.org/article/ae153d29d2504027a3260007b71c5166
Autor:
Daniel Yerly, Yuri Andreiw Pompeu, Ryan J. Schutte, Klara. K. Eriksson, Anette Strhyn, Austin. W. Bracey, Soren Buus, David A. Ostrov
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 7, p 1464 (2017)
Adverse drug reactions are one of the leading causes of morbidity and mortality in health care worldwide. Human leukocyte antigen (HLA) alleles have been strongly associated with drug hypersensitivities, and the causative drugs have been shown to sti
Externí odkaz:
https://doaj.org/article/95325c29288e461884f140cf1f9c27fd
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68902 (2013)
We have recently developed a high-density photolithographic, peptide array technology with a theoretical upper limit of 2 million different peptides per array of 2 cm(2). Here, we have used this to perform complete and exhaustive analyses of linear B
Externí odkaz:
https://doaj.org/article/b47aac887f2f4753b84a84f92115be26