A GPCR-based yeast biosensor for biomedical, biotechnological, and point-of-use cannabinoid determination

Autor: Karel Miettinen, Nattawat Leelahakorn, Aldo Almeida, Yong Zhao, Lukas R. Hansen, Iben E. Nikolajsen, Jens B. Andersen, Michael Givskov, Dan Staerk, Søren Bak, Sotirios C. Kampranis

Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)

GPCRs are used for diverse sensing in eukaryotes. Here the authors use GPCRs to construct yeast-based biosensors, focussing on cannabinoids, and use these to screen agonists and antagonists, as well as generate a portable detection device.

Externí odkaz: https://doaj.org/article/cececb693c5041f0a2967468996b8660

Cellular localization of biosynthesis and breakdown of cyanogenic glucosides in Lotus japonicus

Autor: Anne Vinther Morant, Winnie Dam, Birger Lindberg Møller, Bodil Jørgensen, Soren Bak

Publikováno v: Rasmussen, A V, Dam, W, Lindberg Møller, B, Jørgensen, B & Bak, S 2005, Cellular localization of biosynthesis and breakdown of cyanogenic glucosides in Lotus japonicus . in Plant Biology 2005. The Annual Meeting of the American Society of Plant Biologists. Seattle, Washington, USA, July . pp. 605, Seattle, Washington, United States, 18/07/2005 .
University of Copenhagen
Rasmussen, A V, Dam, W, Møller, B L, Jørgensen, B & Bak, S 2006, Cellular localization of biosynthesis and breakdown of cyanogenic glucosides in Lotus japonicus . in Plant Biotech Denmark Annual Meeting, Products: 7 ., KVL, Copenhagen, Denmark, 01/02/2006 .

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::3ca72e75bc89d715fef159ac6762b3b1
https://pure.au.dk/portal/da/publications/cellular-localization-of-biosynthesis-and-breakdown-of-cyanogenic-glucosides-in-lotus-japonicus(2e835490-bc61-11db-8e26-000ea68e967b).html

Variation of chemical compounds in wild Heliconiini reveals ecological factors involved in the evolution of chemical defenses in mimetic butterflies

Autor: Ombeline Sculfort, Erika C. P. deCastro, Krzysztof M. Kozak, Søren Bak, Marianne Elias, Bastien Nay, Violaine Llaurens

Publikováno v: Ecology and Evolution, Vol 10, Iss 5, Pp 2677-2694 (2020)

Abstract Evolutionary convergence of color pattern in mimetic species is tightly linked with the evolution of chemical defenses. Yet, the evolutionary forces involved in natural variations of chemical defenses in aposematic species are still understu

Externí odkaz: https://doaj.org/article/386d90c0cd90477b896a149359761bca

Evolution of Structural Diversity of Triterpenoids

Autor: Pablo D. Cárdenas, Aldo Almeida, Søren Bak

Publikováno v: Frontiers in Plant Science, Vol 10 (2019)

Plants have evolved to produce a blend of specialized metabolites that serve functional roles in plant adaptation. Among them, triterpenoids are one of the largest subclasses of such specialized metabolites, with more than 14,000 known structures. Th

Externí odkaz: https://doaj.org/article/88c3eb2c7a074688ab1a5762b1f109de

Low Incidence of Atrial Fibrillation in Patients with Transient Ischemic Attack

Autor: Kenneth Bruun Pedersen, Alexander Chemnitz, Charlotte Madsen, Niels C.F. Sandgaard, Søren Bak, Axel Brandes

Publikováno v: Cerebrovascular Diseases Extra, Vol 6, Iss 3, Pp 140-149 (2016)

Background: Atrial fibrillation (AF) is a major cause of stroke. Therefore, all patients with ischemic stroke or transient ischemic attack (TIA) should be examined with 12-lead electrocardiogram (ECG) and continuous monitoring to detect AF. Current g

Externí odkaz: https://doaj.org/article/3ef17f405125401ebf72373b84c8d0cf