Zobrazeno 1 - 10
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pro vyhledávání: '"Sorell L"'
Autor:
Pillai, Nikhil, Craig, Morgan, Dokoumetzidis, Aristeidis, Schwartz, Sorell L., Bies, Robert, Freedman, Immanuel
Publikováno v:
In Progress in Biophysics and Molecular Biology November 2018 139:23-30
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 383:217-226
Modeling and simulation of the central nervous system provides a tool for understanding and predicting the distribution of small molecules throughout the brain tissue and cerebral spinal fluid (CSF), and these efforts often rely on empirical data to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dfbfdeab87b4e04e48242e9b3123f0f
https://doi.org/10.1124/jpet.122.001256
https://doi.org/10.1124/jpet.122.001256
Akademický článek
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Publikováno v:
In Vaccine 7 June 2013 31(25):2738-2743
Publikováno v:
Journal of Pharmacokinetics and Pharmacodynamics
Bridging fundamental approaches to model optimization for pharmacometricians, systems pharmacologists and statisticians is a critical issue. These fields rely primarily on Maximum Likelihood and Extended Least Squares metrics with iterative estimatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a2bb2f91afdefb645620d27d93a6123
https://doi.org/10.1007/s10928-019-09629-4
https://doi.org/10.1007/s10928-019-09629-4
Autor:
Margo Peyton, Jaeil Ahn, Xiaoguang Liu, Alan J. Fowler, Michaeline Hebron, Sara Matar, Joy Arellano, Nadia Yusuf, Barbara Wilmarth, Charbel Moussa, Sorell L. Schwartz, Nathan J. Starr, Helen H. Howard, Fernando Pagan, Yasar Torres-Yaghi, Elizabeth E. Mundel, Abigail Lawler
Publikováno v:
Pharmacology Research & Perspectives
Nilotinib is a broad‐based tyrosine kinase inhibitor with the highest affinity to inhibit Abelson (c‐Abl) and discoidin domain receptors (DDR1/2). Preclinical evidence indicates that Nilotinib reduces the level of brain alpha‐synuclein and atte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71eff89df2d80ff2d3ac18c9fbf3a382
https://pubmed.ncbi.nlm.nih.gov/30906562
https://pubmed.ncbi.nlm.nih.gov/30906562
Autor:
Charbel Moussa, Jaeil Ahn, Yasar Torres-Yaghi, Sorell L. Schwartz, Abigail Lawler, Barbara Wilmarth, Ashot Shekonyan, Michaeline Hebron, Ellen Valladez, Helen Howard, Fernando Pagan
Publikováno v:
SSRN Electronic Journal.
Background: Parkinson's disease (PD) involves motor and non-motor symptoms and loss of brain dopamine neurons. Nilotinib is a tyrosine kinase inhibitor that may alter brain dopamine metabolism. Methods: A phase II randomized, double-blind, placebo co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05a65cf5b039c0fde6bbb2adea07774a
https://doi.org/10.2139/ssrn.3397207
https://doi.org/10.2139/ssrn.3397207
Autor:
Cremata, J.A.1 Jose.cremata@cigb.edu.cu, Sorell, L.2, Montesino, R.1, García, R.1, Mata, M.1, Cabrera, G.1, Galvan, J.A.2, García, G.3, Valdés, R.4, Garrote, J.A.5
Publikováno v:
Clinical & Experimental Immunology. Sep2003, Vol. 133 Issue 3, p422. 8p.
Publikováno v:
Science, 1969 Jan . 163(3865), 395-397.
Externí odkaz:
https://www.jstor.org/stable/1725026
Introduction. Synthesis and Properties of PVP. Movement of Large Molecules Across Membranes-General Considerations. Absorption of PVP by Various Routes of Administration. Excretion and Metabolism of PVP. Distribution and Storage of PVP. Storage of PV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43d57fb6f79492c4de11dbf1422ce826
https://doi.org/10.1201/9780203741672
https://doi.org/10.1201/9780203741672
