Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Sorcha Finnegan"'
Autor:
Bettina C. Schock, Jose R. Naranjo, Marie Héritier, Sorcha Finnegan, George Momtazi, Amal Elbanna, Lois Lavery, Kirsten Mccollum
Publikováno v:
Airway cell biology and immunopathology.
Chronic, exaggerated inflammation in response to infection is characteristic for Cystic Fibrosis (CF) lung disease. Novel CF therapeutics overcome the underlying functional defect in the cystic fibrosis transmembrane conductance regulator (CFTR), but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f31bd1c5b9d345e7d4f86aaed69d2e9
https://doi.org/10.1183/13993003.congress-2019.pa2371
https://doi.org/10.1183/13993003.congress-2019.pa2371
Autor:
Colm O'Brien, Stephen M. J. Farrell, Thomas G. Cotter, Gillian Groeger, Sorcha Finnegan, Lavinia Bhatt
Publikováno v:
European Journal of Neuroscience. 33:632-641
In many retinal diseases, it is the death of photoreceptors that leads to blindness. In previous in vitro and in vivo studies, basic fibroblast growth factor (bFGF) has been shown to increase retinal cell survival. More recently, reactive oxygen spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6cb40764cff8c2f6d3c64e1de1088de
https://doi.org/10.1111/j.1460-9568.2010.07559.x
https://doi.org/10.1111/j.1460-9568.2010.07559.x
Autor:
Joshua LaBaer, K Barker, Catherine McAllister, EA Mendoza, Sorcha Finnegan, David Gibson, Madeleine Rooney, Ji Qiu
Publikováno v:
Rheumatology.
Method: Nucleic Acid Programmable Protein Array (NAPPA) enables the production of multiple proteins from DNA templates which are immobilized on a solid phase. These can then be probed for the presence of autoantibodies in patient’s serum. NAPPA sli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1573fa94ec056e31741d45909d1f667
https://doi.org/10.1093/rheumatology/keu268.003
https://doi.org/10.1093/rheumatology/keu268.003
Autor:
Catherine McAllister, Sorcha Finnegan, Stephen R. Pennington, David Gibson, Joanne L. Robson, Caitriona Scaife, Madeleine Rooney
Publikováno v:
Arthritis Research & Therapy
Finnegan, S, Robson, J, Scaife, C, McAllister, C, Pennington, S R, Gibson, D S & Rooney, M E 2014, ' Synovial membrane protein expression differs between juvenile idiopathic arthritis subtypes in early disease ', Arthritis Research & Therapy, vol. 16, no. 1, R8 . https://doi.org/10.1186/ar4434
Arthritis research & therapy, 2014, Vol.16, pp.R8 [Peer Reviewed Journal]
Finnegan, S, Robson, J, Scaife, C, McAllister, C, Pennington, S R, Gibson, D S & Rooney, M E 2014, ' Synovial membrane protein expression differs between juvenile idiopathic arthritis subtypes in early disease ', Arthritis Research & Therapy, vol. 16, no. 1, R8 . https://doi.org/10.1186/ar4434
Arthritis research & therapy, 2014, Vol.16, pp.R8 [Peer Reviewed Journal]
Introduction: Juvenile idiopathic arthritis (JIA) is the most common rheumatological disease of childhood with a prevalence of around 1 in 1000. Without appropriate treatment it can have devastating consequences including permanent disability from jo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faf0abc493863dc22478c52e9296e086
https://pubmed.ncbi.nlm.nih.gov/24410838
https://pubmed.ncbi.nlm.nih.gov/24410838
Autor:
Catherine McAllister, Sorcha Finnegan, Alexandra N. Evans, Caitriona Scaife, Stephen R. Pennington, Keri Newell, David Gibson, Mark W. Duncan, Madeleine Rooney, Gwen Manning, Terry L. Moore
Publikováno v:
Gibson, D S, Newell, K, Evans, A N, Finnegan, S, Manning, G, Scaife, C, McAllister, C, Pennington, S R, Duncan, M W, Moore, T L & Rooney, M E 2012, ' Vitamin D binding protein isoforms as candidate predictors of disease extension in childhood arthritis ', Journal of proteomics, vol. 75, no. 17, pp. 5479-5492 . https://doi.org/10.1016/j.jprot.2012.06.024
Journal of Proteomics
Journal of Proteomics
Introduction. Juvenile idiopathic arthritis (JIA) comprises a poorly understood group of chronic autoimmune diseases with variable clinical outcomes. We investigated whether the synovial fluid (SF) proteome could distinguish a subset of patients in w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87461c78203d58a280a119a72797ac0e
https://pure.qub.ac.uk/en/publications/vitamin-d-binding-protein-isoforms-as-candidate-predictors-of-disease-extension-in-childhood-arthritis(3236e61a-1e45-45e0-8407-8a552fe6008d).html
https://pure.qub.ac.uk/en/publications/vitamin-d-binding-protein-isoforms-as-candidate-predictors-of-disease-extension-in-childhood-arthritis(3236e61a-1e45-45e0-8407-8a552fe6008d).html
Autor:
Joshua LaBaer, Mark W. Duncan, David Gibson, Sorcha Finnegan, Stephen R. Pennington, Ji Qiu, David C. Thompson, Madeleine Rooney
Publikováno v:
Rheumatology (Oxford, England). 51(3)
This review examines the biomarker development process by using rheumatic disorders as the disease model for discussion. We evaluate the current role of biomarkers in the practice of rheumatology and discuss their likely role in the future. We define
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::663841993034c1e8cfc2271c610cea37
https://pubmed.ncbi.nlm.nih.gov/22179724
https://pubmed.ncbi.nlm.nih.gov/22179724
Autor:
David Gibson, Madeleine Rooney, Stephen R. Pennington, Joshua LaBaer, Sorcha Finnegan, Mark W. Duncan, Ji Qiu
Publikováno v:
Autoimmune Disorders-Current Concepts and Advances from Bedside to Mechanistic Insights
Despite the anticipated boom stemming from proteomic investigations, the rate at whichnovel protein biomarkers are introduced into clinical practice has remained static over thepast 20 years. The reality is that approaches to both discover and valida
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa756a8586cc3c0cad0cdef2492e5777
http://www.intechopen.com/articles/show/title/validation-of-protein-biomarkers-to-advance-the-management-of-autoimmune-disorders
http://www.intechopen.com/articles/show/title/validation-of-protein-biomarkers-to-advance-the-management-of-autoimmune-disorders
Autor:
Hussain Jafri, Samuel G. Jacobson, Katrina Prescott, Manir Ali, Sorcha Finnegan, Paul Hocking, Mike Shires, Douglas H. Lester, James A. Poulter, David A. Mackey, William J. Curry, Jonathan B Ruddle, Martin McKibbin, Chris F. Inglehearn, Adam Booth, David W. Burt, Yasmin Raashid, Carmel Toomes
Publikováno v:
Investigative ophthalmologyvisual science. 52(10)
Purpose. To identify the defective gene in the sex-linked, recessively inherited retinal dysplasia and degeneration (rdd) chicken and to search for the human equivalent disease. Methods. Microsatellites from chicken chromosome Z were genotyped in 77
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acf780ae64c4d9e6ceb3e9ccbca1712e
https://pubmed.ncbi.nlm.nih.gov/21862650
https://pubmed.ncbi.nlm.nih.gov/21862650
Publikováno v:
Annals of the rheumatic diseases. 70(10)
ObjectiveJuvenile idiopathic arthritis (JIA) consists of a heterogeneous group of inflammatory disorders, within which there are a number of clinical subgroups. Diagnosis and assignment to a particular subgroup can be problematical and more concise m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c697b8ca5d5c59a7ff8f79eafbf4d5c
https://pubmed.ncbi.nlm.nih.gov/21685110
https://pubmed.ncbi.nlm.nih.gov/21685110
Autor:
Stephen M J, Farrell, Gillian, Groeger, Lavinia, Bhatt, Sorcha, Finnegan, Colm J, O'Brien, Thomas G, Cotter
Publikováno v:
The European journal of neuroscience. 33(4)
In many retinal diseases, it is the death of photoreceptors that leads to blindness. In previous in vitro and in vivo studies, basic fibroblast growth factor (bFGF) has been shown to increase retinal cell survival. More recently, reactive oxygen spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d73d85255f051b6ad136ded8681aa079
https://pubmed.ncbi.nlm.nih.gov/21219477
https://pubmed.ncbi.nlm.nih.gov/21219477