Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Soraya O. Sandoval"'
Publikováno v:
Journal of Neurodevelopmental Disorders, Vol 16, Iss 1, Pp 1-11 (2024)
Abstract Fragile X syndrome (FXS) is caused by epigenetic silencing of the X-linked fragile X messenger ribonucleoprotein 1 (FMR1) gene located on chromosome Xq27.3, which leads to the loss of its protein product, fragile X messenger ribonucleoprotei
Externí odkaz:
https://doaj.org/article/f0a20d8c80fb4694875f9c08b82b7c58
Autor:
Chenfeng He, Noah Cohen Kalafut, Soraya O. Sandoval, Ryan Risgaard, Carissa L. Sirois, Chen Yang, Saniya Khullar, Marin Suzuki, Xiang Huang, Qiang Chang, Xinyu Zhao, Andre M.M. Sousa, Daifeng Wang
Publikováno v:
Cell Reports: Methods, Vol 3, Iss 2, Pp 100409- (2023)
Summary: Our machine-learning framework, brain and organoid manifold alignment (BOMA), first performs a global alignment of developmental gene expression data between brains and organoids. It then applies manifold learning to locally refine the align
Externí odkaz:
https://doaj.org/article/494be02e96414fa5a14749b2ddcb4ea7
Autor:
Chenfeng He, Noah Cohen Kalafut, Soraya O. Sandoval, Ryan Risgaard, Chen Yang, Saniya Khullar, Marin Suzuki, Qiang Chang, Xinyu Zhao, Andre M.M. Sousa, Daifeng Wang
Organoids have become valuable models for understanding cellular and molecular mechanisms in human development including brains. However, whether developmental gene expression programs are preserved between human organoids and brains, especially in s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6cd1817ebf1250a3f939ebe701e40ab2
https://doi.org/10.1101/2022.06.13.495946
https://doi.org/10.1101/2022.06.13.495946
