PBMC therapy reduces cell death and tissue fibrosis after acute kidney injury by modulating the pattern of monocyte/macrophage survival in tissue

Autor: Selene Torrico, Georgina Hotter, Ángeles Muñoz, Priscila Calle, Miriam García, Esteban Poch, Soraya Játiva

Publikováno v: Biomedicine & Pharmacotherapy, Vol 178, Iss , Pp 117186- (2024)

In this study, we investigated if the therapeutic potential of peripheral blood mononuclear cell (PBMC) therapy in a murine model of ischemic AKI is related with the survival pattern of monocyte/macrophages in tissue. CD-1 mice were subjected to bila

Externí odkaz: https://doaj.org/article/6c21c474b8fe499aa550a99aa30820bb

Mitochondrial Transplantation Enhances Phagocytic Function and Decreases Lipid Accumulation in Foam Cell Macrophages

Autor: Soraya Játiva, Priscila Calle, Selene Torrico, Ángeles Muñoz, Miriam García, Ivet Martinez, Anna Sola, Georgina Hotter

Publikováno v: Biomedicines, Vol 10, Iss 2, p 329 (2022)

Macrophages have mechanisms for eliminating cholesterol from cells. If excess cholesterol is not eliminated from the macrophages, then transformation into a foam cell may occur. Foam cells are a hallmark of the atherosclerotic lesions that contribute

Externí odkaz: https://doaj.org/article/6853bf19dc7044afb561711e4da14f19

Mitotic Exit Function of Polo-like Kinase Cdc5 Is Dependent on Sequential Activation by Cdk1

Autor: Jose-Antonio Rodriguez-Rodriguez, Yolanda Moyano, Soraya Játiva, Ethel Queralt

Publikováno v: Cell Reports, Vol 15, Iss 9, Pp 2050-2062 (2016)

To complete mitosis, Saccharomyces cerevisiae needs to activate the mitotic phosphatase Cdc14. Two pathways contribute to Cdc14 regulation: FEAR (Cdc14 early anaphase release) and MEN (mitotic exit network). Cdc5 polo-like kinase was found to be an i

Externí odkaz: https://doaj.org/article/ff4870aa2dd5409489832c91c9290416

Infusion of phagocytic macrophages overexpressing cpt1a ameliorates kidney fibrosis in the UUO model

Autor: Laura Herrero, Paula Mera, Dolors Serra, Angeles Muñoz, Selene Torrico, Priscila Calle, Georgina Hotter, Anna M. Solà, Soraya Játiva, Miriam García

Publikováno v: Dipòsit Digital de la UB
Universidad de Barcelona
Cells
Volume 10
Issue 7
Cells, Vol 10, Iss 1650, p 1650 (2021)
Digital.CSIC. Repositorio Institucional del CSIC
instname

Phagocytosis is an inherent function of tissue macrophages for the removal of apoptotic cells and cellular debris during acute and chronic injury; however, the dynamics of this event during fibrosis development is unknown. We aim to prove that during

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df5346f6f841472f674c44600eada88f
http://hdl.handle.net/10261/260299

SILAC-based phosphoproteomics reveals new PP2A-Cdc55-regulated processes in budding yeast

Autor: Ines Calabria, Judith Vinaixa, Concha Gil, Soraya Játiva, Silvia Barceló-Batllori, Martin R. Larsen, Ethel Queralt, João P. G. L. M. Rodrigues, Carolina de LaTorre, María Luisa Hernáez, Joan-Josep Bech-Serra, Barbara Baro

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname
Dipòsit Digital de la UB
Universidad de Barcelona
Baro, B, Játiva, S, Calabria, I, Vinaixa, J, Bech-Serra, J-J, de LaTorre, C, Rodrigues, J, Hernáez, M L, Gil, C, Barceló-Batllori, S, Larsen, M R & Queralt, E 2018, ' SILAC-based phosphoproteomics reveals new PP2A-Cdc55-regulated processes in budding yeast ', GigaScience, vol. 7, no. 5, giy047 . https://doi.org/10.1093/gigascience/giy047
GigaScience
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe

18 páginas, 5 figuras, 1 tabla
Background: Protein phosphatase 2A (PP2A) is a family of conserved serine/threonine phosphatases involved in several essential aspects of cell growth and proliferation. PP2ACdc55 phosphatase has been extensively r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e49adbe03cb62da24c3b0b0fc26b71b
http://hdl.handle.net/10261/272296