Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Soraya E. Gutierrez"'
Autor:
Silvana P. Jiménez, Jacek K. Wychowaniec, Soraya E. Gutierrez, Matias Jimenez, Francisco J. Verdugo-Avello
Publikováno v:
Cell and Tissue Banking
The transplantation of tissues can save lives and re-establish vital functions, where no alternatives of comparable effectiveness exist. This has led to establishment of tissue transplantation as a successful practice worldwide; however, a great vari
Autor:
Milka Martinez, Marcela Hinojosa, Daniel Trombly, Violeta Morin, Janet Stein, Gary Stein, Amjad Javed, Soraya E Gutierrez
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0149119 (2016)
RUNX1 a member of the family of runt related transcription factors (RUNX), is essential for hematopoiesis. The expression of RUNX1 gene is controlled by two promoters; the distal P1 promoter and the proximal P2 promoter. Several isoforms of RUNX1 mRN
Externí odkaz:
https://doaj.org/article/07c882e205444f1dbae6375f29ee6612
Publikováno v:
Human Genomics
Human Genomics, Vol 13, Iss 1, Pp 1-9 (2019)
Human Genomics, Vol 13, Iss 1, Pp 1-9 (2019)
Background RUNX1 gene, a master regulator of the hematopoietic process, participates in pathological conditions as a partner for several genes in chromosomal translocations. One of the most frequent chromosomal translocations found in acute myeloid l
Autor:
Soraya E. Gutierrez, Giorgia D. Ugarte, Giancarlo V. De Ferrari, Macarena F. Vargas, Alvaro A. Elorza, Miguel E. Avila, Matías A. Medina, David Necuñir
Publikováno v:
Journal of Cellular Physiology. 231:1460-1467
Two distantly located promoter regions regulate the dynamic expression of RUNX genes during development: distal P1 and proximal P2 promoters. We have recently described that β-catenin increases total Runx1 mRNA levels in human CD34(+) hematopoietic
Autor:
Amjad Javed, Mitra Adhami, Rosa Serra, Soraya E. Gutierrez, Harunur Rashid, Farah Y. Ghori-Javed, Haiyan Chen
Publikováno v:
Journal of Bone and Mineral Research. 29:2653-2665
Synthesis of cartilage by chondrocytes is an obligatory step for endochondral ossification. Global deletion of the Runx2 gene results in complete failure of the ossification process, but the underlying cellular and molecular mechanisms are not fully
Autor:
Soraya E. Gutierrez, Nicolás Schnake
Publikováno v:
Leukemia Research Reports, Vol 12, Iss, Pp-(2019)
In this work, we analyzed the association between RUNX1 gene expression and the accessibility of BCR3, one of RUNX1 gene breakpoint regions involved in the chromosomal translocation (8;21), a frequent translocation in treatment-related acute myeloid
Publikováno v:
Journal of Cellular Biochemistry. 114:2569-2576
One of the most frequent chromosomal translocation found in patients with acute myeloid leukemia (AML) is the t(8;21). This translocation involves the RUNX1 and ETO genes. The breakpoints regions for t(8;21) are located at intron 5 and intron 1 of th
Autor:
Soraya E. Gutierrez, Jane B. Lian, Gary S. Stein, Marcela Stuardo, Karla Hidalgo, Amjad Javed, Martin Montecino, Milka Martinez, Janet L. Stein
Publikováno v:
JOURNAL OF CELLULAR PHYSIOLOGY
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
The RUNX1/AML1 gene is the most frequent target for chromosomal translocation, and often identified as a site for reciprocal rearrangement of chromosomes 8 and 21 in patients with acute myelogenous leukemia. Virtually all chromosome translocations in
Autor:
Amjad Javed, Sarah L. Dallas, Mitsuhiro Enjo, Jeffrey A. Winkles, Bernd Grohe, Colette A. Inkson, David W. Rowe, Tatiana Foroud, Jim Simmer, Hitesh Kapadia, Chi P. Lee, Frédéric Lézot, Chunxi Ge, Bill Daly, Ryuichi Fujisawa, Jason O’Young, Izabela Maciejewska, Ana Carolina Acevedo, Hua Wu, Yanming Bi, L. Lausten, L.F. Bonewald, Matthew R. Allen, Patricia A. Veno, Hongshan Zhao, Laurie K. McCauley, Dominique Hotton, Mina Mina, Soraya E. Gutierrez, Wu Li, Faiza Afzal, Johanne LeBihan, Dana Olton, Hailan Feng, Elizabeth Lowder, L.M. Paula, Nabil G. Seidah, Gabriele Mues, Larry W. Fisher, Masato Tamura, Tao Peng, Z. Schwartz, J. Katz, Marjorie Weaver, Jolene Bohensky, Dong Yan, William T. Butler, Ling Ye, Sara Jeffrey, Ejvis Lamani, Jinhua Li, Daming Fan, Kurtulus Golcuk, Eric T. Everett, Carolyn W. Gibson, Muhanad Aïoub, M. Johnson, Peter S. N. Rowe, Ming Zhong, Lynda F. Bonewald, J.R. Néfussi, Gérard Goubin, Noritaka Isogai, A.C. Acevedo, Yong Li, Harvey A. Goldberg, Janet Moradian-Oldak, Yan Li, Vickram Srinivas, M.T. Hincke, C. Barragan-Adjemian, Thuan Le, Bat Ami Gotliv, Yuka Shinmura, Xiaoxia Zhang, Martin Montecino, Yixia Xie, Xiaowei Su, Paul H. Krebsbach, Sharon Segvich, Michèle Garabédian, Joseph M. Wallace, Frederick H. Silver, Li Zhu, Chaoying Cui, Mohammad Q. Hassan, Laurence Pibouin, Sharanjot Saini, Jian Q. Feng, Mila Spevak, Ivo Kalajzic, Sergei A. Kuznetsov, M.D. McKee, Chunlin Qin, Renny T. Franceschi, Esben S. Sørensen, Sylvie Babajko, Laurent Ameye, Barbara Rodgers, Di Jiang, Mireille Bonnefoix, Yixin Wu, Michel Goldberg, Janet L. Stein, Bingzhen Huang, Coralee E. Tye, Robin Jacquet, Mikko Karttunen, Michael D. Morris, Rachel L. Lorenz, Karl J. Jepsen, Pamela DenBesten, J. Timothy Wright, Zhi-An Yuan, Yoshinori Shinohara, Chad M. Novince, Jane B. Lian, Rajamani Lakshminarayanan, Wilbur Tong, Jingfeng Wu, W. Kim Seow, Hyon Jong Kim, John D. Bartlett, Lixiang Liu, Céline Gaucher, Sharon B. Midura, Zvi Schwartz, Sara Chirico, Alastair James Sloan, Nehal Al Tarhuni, Shuo Chen, Hernan Roca, Petros Papagerakis, Adele L. Boskey, Ellen P. Henderson, Darrell H. Carney, Donghyun Lee, Irving M. Shapiro, Tchilalo Boukpessi, David H. Kohn, Graeme K. Hunter, Dominique Septier, Yoshitaka Wada, Amit Vasanji, Juan Dong, Urban Lindgren, Hayden William Courtland, Jan C.-C. Hu, Guozhi Xiao, Mark Stephen Litaker, Brent B. Ward, Nan E. Hatch, James P. Simmer, Marian F. Young, Stéphane Petit, Chang Du, B.D. Boyan, Fleur Meary, Ashok B. Kulkarni, M. MacDougall, Arthur Veis, Gabrielle Mues, Kaleem Zaidi, Mitsuaki Ono, Zhi Sun, E. Angeles Martinez-Mier, Subhashis Biswas, Isabelle Fernandes, Thomas C. Hart, Jong-Sup Bae, Cynthia Suggs, Mildred C. Embree, Shelley E. Brown, Jonathan A. R. Gordon, Jerry Q. Feng, Nadder D. Sahar, Prashant N. Kumta, William J. Landis, Jitesh Pratap, Melissa Aragon, Rachel J. Waddington, J. Dong, Udo Becker, Kotaro Tanimoto, Andre J. van Wijnen, Rena N. D'Souza, Ronald J. Midura, Yongbo Lu, Jan Hu, Anamaria Balic, Jeffrey P. Gorski, Charles Sfeir, Ying Wang, Yao Sun, Frédéric Jehan, Darrin Simmons, Mary MacDougall, Bill Daley, Disheng Qin, Yuanyuan Hu, Masaki J. Honda, Hanson Fong, L.J.S. Santos, P. Suzanne Hart, Gary S. Stein, Tina M. Kilts, Catherine Chaussain-Miller, Y.-C. Chien, Lars-Arne Haldosén, D.B. Ang, Barbara D. Boyan, Muriel Molla, Sarah Jane Youde, Thorsten Kirsch, Ariane Berdal, Jennifer Rosser, Morimichi Mizuno, Yuwei Fan, Kathy K.H. Svoboda, Nichole T. Huffman, James T. Ryaby, Carl-Magnus Bäckesjö, Cielo Barragan-Adjemian
Publikováno v:
Cells Tissues Organs. 189:295-302
Autor:
Jane B. Lian, Gary S. Stein, Amjad Javed, Andre J. van Wijnen, Soraya E. Gutierrez, Sayyed K. Zaidi, Yang Lou, Faiza Afzal, Janet L. Stein, Jong-Sup Bae, Jitesh Pratap
Publikováno v:
Journal of Biological Chemistry. 283:8412-8422
Two regulatory pathways, bone morphogenetic protein (BMP)/transforming growth factor-β (TGFβ) and the transcription factor RUNX2, are required for bone formation in vivo. Here we show the interdependent requirement of these pathways to induce an os