Výsledky vyhledávání - "Soraya Adris"

IL-12 and IL-10 Expression Synergize to Induce the Immune-Mediated Eradication of Established Colon and Mammary Tumors and Lung Metastasis

Autor: Yuti Chernajovsky, Soraya Adris, Alicia I. Bravo, M. Verónica Lopez, Osvaldo L. Podhajcer

Publikováno v: The Journal of Immunology. 175:5885-5894

Preclinical studies demonstrated that certain cytokines are potentially useful for the induction of antitumor immune responses. However, their administration in clinical settings was only marginally useful and evoked serious toxicity. In this study,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce651e244f6b3c86673315d15379e254
https://doi.org/10.4049/jimmunol.175.9.5885

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The Expression of the Secreted Protein Acidic and Rich in Cysteine (SPARC) Is Associated with the Neoplastic Progression of Human Melanoma

Autor: Alicia I. Bravo, Laura Bover, Soraya Adris, Osvaldo L. Podhajcer, Jose Mordoh, Fernanda Ledda

Publikováno v: Journal of Investigative Dermatology. 108(2):210-214

SPARC (secreted protein acidic and rich in cysteine) is an extracellular protein associated with tissues exhibiting high rates of cell proliferation and matrix remodeling. The current work shows that the human melanoma cell lines IIB-MEL-LES, IIB-MEL

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::189214eaeed5bea50367b3dba5137047

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Quantification of vascular endothelial growth factor and neuropilins mRNAs during rat brain maturation by real-time PCR

Autor: Soraya Adris, Mario Hugo Las Glicinas y Los Jazmines Genero, Pablo Argibay, Elizabeth Edit Las Glicinas y Los Jazmines Ojeda

Publikováno v: Cellular and molecular neurobiology. 25(6)

1. Vascular endothelial growth factor (VEGF) has been related with several brain functions such as angiogenesis, neuroprotection, and neurogenesis. 2. We studied the mRNA expression of the two most important isoforms of VEGF (VEGF120 and VEGF164) as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88a6c9388bd91d0f56fb93f06366409e
https://pubmed.ncbi.nlm.nih.gov/16392034

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IL-10 expression by CT26 colon carcinoma cells inhibits their malignant phenotype and induces a T cell-mediated tumor rejection in the context of a systemic Th2 response

Autor: S Klein, Alicia I. Bravo, Cecilia Carbone, Yuti Chernajovsky, Maria A. Jasnis, M. F. Ledda, Osvaldo L. Podhajcer, Eduardo Chuluyan, Soraya Adris

Publikováno v: SEDICI (UNLP)
Universidad Nacional de La Plata
instacron:UNLP

In spite of the evidence that IL-10 has Th1-immunosuppressive and anti-inflammatory effects, it has been shown that IL-10 may reduce the tumorigenic capacity of certain tumor cell types. In order to characterize the responses elicited by IL-10, we ex

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9365c336c062dd7e8c0163cc37a3787
https://pubmed.ncbi.nlm.nih.gov/10516719

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Different efficacy of in vivo herpes simplex virus thymidine kinase gene transduction and ganciclovir treatment on the inhibition of tumor growth of murine and human melanoma cells and rat glioblastoma cells

Autor: Mariana Berenstein, Alicia I. Bravo, José Mordoh, Fernanda Ledda, Osvaldo L. Podhajcer, Jorge H. Medina, Claudia Wolfmann, Soraya Adris, Yuti Chernajovsky

Publikováno v: Cancer gene therapy. 6(4)

Initial studies have demonstrated the therapeutic efficacy for cancer treatment of in vivo transfer of the herpes simplex virus thymidine kinase gene followed by ganciclovir (GCV) treatment. However, recent studies have questioned the validity of thi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d566eb6e37391953d51bd16cd2b83510
https://pubmed.ncbi.nlm.nih.gov/10419054

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Suppression of SPARC expression by antisense RNA abrogates the tumorigenicity of human melanoma cells

Autor: M. Fernanda Ledda, Alicia I. Bravo, Soraya Adris, Osvaldo L. Podhajcer, Laura Bover, Claudia Kairiyama, José Mordoh, Yuti Chernajovsky

Publikováno v: Nature medicine. 3(2)

Acquisition of invasive/metastatic potential is a key event in tumor progression. Cell surface glycoproteins and their respective matrix ligands have been implicated in this process. Recent evidence reveals that the secreted glycoprotein SPARC (secre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5e1e2bf0da81797d6e054c6988f845c
https://pubmed.ncbi.nlm.nih.gov/9018235

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