Aedes aegypti salivary gland extract alleviates acute itching by blocking TRPA1 channels

Autor: Anderson R. A. Cerqueira, Leandro Rodrigues, Silvia Abigail Coavoy-Sánchez, Simone A. Teixeira, Karla B. Feitosa, Erika Y. Taniguchi, Lucia R. Lopes, Antônio C. Cassola, Marcelo N. Muscará, Anderson Sá-Nunes, Soraia K. P. Costa

Publikováno v: Frontiers in Physiology, Vol 14 (2023)

Aedes aegypti (Ae. aegypti) saliva induces a variety of anti-inflammatory and immunomodulatory activities. Interestingly, although it is known that mosquito bites cause allergic reactions in sensitised hosts, the primary exposure of humans to Ae. aeg

Externí odkaz: https://doaj.org/article/e564797005a04b56ad4db63d1eb532d9

Myrtenol Reduces Orofacial Nociception and Inflammation in Mice Through p38-MAPK and Cytokine Inhibition

Autor: Janaíne P. Oliveira, Fabíula F. Abreu, José Marcos M. Bispo, Anderson R. A. Cerqueira, José Ronaldo dos Santos, Cristiane B. Correa, Soraia K. P. Costa, Enilton A. Camargo

Publikováno v: Frontiers in Pharmacology, Vol 13 (2022)

Orofacial pain is one of the commonest and most complex complaints in dentistry, greatly impairing life quality. Preclinical studies using monoterpenes have shown pharmacological potential to treat painful conditions, but the reports of the effects o

Externí odkaz: https://doaj.org/article/d17c35e93f6a44229794a35931bf5bcf

Vasorelaxant activity of AP39, a mitochondria-targeted H2S donor, on mouse mesenteric artery rings in vitro

Autor: Leonardo A. da Costa da Costa Marques, Simone A. Teixeira, Flávia N. de de Jesus, Mark E. Wood, Roberta Torregrossa, Matthew Whiteman, Soraia K. P. Costa, Marcelo N. Muscará

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Biomolecules; Volume 12; Issue 2; Pages: 280

Mitochondria-targeted hydrogen sulfide (H2S) donor compounds, such as compound AP39, supply H2S into the mitochondrial environment and have shown several beneficial in vitro and in vivo effects in cardiovascular conditions such as diabetes and hypert

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ddede9a24459dd98178837c037de945

Pulmonary inflammation is regulated by the levels of the vesicular acetylcholine transporter.

Autor: Nathalia M Pinheiro, Claudia J C P Miranda, Adenir Perini, Niels O S Câmara, Soraia K P Costa, Maria Isabel C Alonso-Vale, Luciana C Caperuto, Iolanda F L C Tibério, Marco Antônio M Prado, Mílton A Martins, Vânia F Prado, Carla M Prado

Publikováno v: PLoS ONE, Vol 10, Iss 3, p e0120441 (2015)

Acetylcholine (ACh) plays a crucial role in physiological responses of both the central and the peripheral nervous system. Moreover, ACh was described as an anti-inflammatory mediator involved in the suppression of exacerbated innate response and cyt

Externí odkaz: https://doaj.org/article/5c8a144fb5534ecdb769651ec04fbc81

Lipopolysaccharide reduces urethral smooth muscle contractility via cyclooxygenase activation

Autor: Fabiano B, Calmasini, Eduardo C, Alexandre, Mariana G, Oliveira, Fábio H, Silva, António G, Soares, Soraia K P, Costa, Edson, Antunes

Publikováno v: Journal of physiology and biochemistry. 77(4)

Lipopolysaccharide (LPS) is a component of gram-negative bacteria wall that elicits inflammatory response in the host through the toll-like receptor 4 (TLR4) activation. In the lower urinary tract (LUT), bacteria-derived LPS has been associated with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5246de66e2b0c0aa921c16e5ad014561
https://pubmed.ncbi.nlm.nih.gov/34018097