Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Soraia Barão"'
Autor:
Soraia Barão, Yijun Xu, José P. Llongueras, Rachel Vistein, Loyal Goff, Kristina J. Nielsen, Byoung-Il Bae, Richard S. Smith, Christopher A. Walsh, Genevieve Stein-O’Brien, Ulrich Müller
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract The neocortex varies in size and complexity among mammals due to the tremendous variability in the number and diversity of neuronal subtypes across species. The increased cellular diversity is paralleled by the expansion of the pool of neoco
Externí odkaz:
https://doaj.org/article/b65bc45bf8dc45989890eae4f1d50f6b
Autor:
Soraia Barão, Annette Gärtner, Eduardo Leyva-Díaz, Galina Demyanenko, Sebastian Munck, Tine Vanhoutvin, Lujia Zhou, Melitta Schachner, Guillermina López-Bendito, Patricia F. Maness, Bart De Strooper
Publikováno v:
Cell Reports, Vol 12, Iss 9, Pp 1367-1376 (2015)
ΒACE1 is the major drug target for Alzheimer’s disease, but we know surprisingly little about its normal function in the CNS. Here, we show that this protease is critically involved in semaphorin 3A (Sema3A)-mediated axonal guidance processes in t
Externí odkaz:
https://doaj.org/article/ed8786a645914ceea5d53358b982e667
Autor:
Isabel Mateos-White, Cristina Gil-Sanz, Jessica Alves Medeiros de Araujo, Soraia Barão Lourenco Barao, Marcos R. Costa, Ana Espinosa, Ulrich Müller
Publikováno v:
Medeiros de Araújo, Jéssica Alves Barão, Soraia Mateos-White, Isabel Espinosa, Ana Costa, Marcos R. Gil-Sanz, Cristina Müller, Ulrich 2021 ZBTB20 is crucial for the specification of a subset of callosal projection neurons and astrocytes in the mammalian neocortex Development 148 16 dev196642
RODERIC. Repositorio Institucional de la Universitat de Valéncia
instname
Development
RODERIC. Repositorio Institucional de la Universitat de Valéncia
instname
Development
Neocortical progenitor cells generate subtypes of excitatory projection neurons in sequential order followed by the generation of astrocytes. The transcription factor zinc finger and BTB domain-containing protein 20 (ZBTB20) has been implicated in re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80b5a52be5d0f494a3e994bb5838ab68
https://hdl.handle.net/10550/82771
https://hdl.handle.net/10550/82771
Autor:
Jennifer Bogert, Johannes Streffer, Bart De Strooper, John Slemmon, Soraia Barão Lourenco Barao, Luc Van Nueten, Bianca Van Broeck, Marc Mercken, Leslie M. Shaw, Ina Tesseur, Katja De Waepenaert, Dieder Moechars, Sebastiaan Engelborghs, Luc Tritsmans, Maarten Timmers
Publikováno v:
Journal of Alzheimer's Disease
Journal of Alzheimer's disease
Journal of Alzheimer's disease
The β-site amyloid-β protein precursor (AβPP) cleaving enzyme-1 (BACE1) is the rate limiting enzyme in the generation of amyloid-β peptide (Aβ) from AβPP, one of the major pathways in Alzheimers disease (AD) pathology. Increased BACE1 levels an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42e97da7a0a5992a8ac4a309ec5e2fbc
http://europepmc.org/articles/PMC5325057
http://europepmc.org/articles/PMC5325057
Publikováno v:
Trends in neurosciences 39(3), 158-169 (2016). doi:10.1016/j.tins.2016.01.003
The protease β-site amyloid precursor protein (APP)-cleaving enzyme 1 (BACE1) is required for the production of the amyloid-β (Aβ) peptide, which is central to the pathogenesis of Alzheimer's disease (AD). Chronic inhibition of this protease may t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cd788aa77b3caea06947fa8f6a5598a
https://doi.org/10.1016/j.tins.2016.01.003
https://doi.org/10.1016/j.tins.2016.01.003
Autor:
Annette Gärtner, Lujia Zhou, Sebastian Munck, Guillermina López-Bendito, Galina P. Demyanenko, Melitta Schachner, Soraia Barão Lourenco Barao, Eduardo Leyva-Díaz, Tine Vanhoutvin, Patricia F. Maness, Bart De Strooper
Publikováno v:
Cell reports
Cell Reports, Vol 12, Iss 9, Pp 1367-1376 (2015)
Cell Reports, Vol 12, Iss 9, Pp 1367-1376 (2015)
ΒACE1 is the major drug target for Alzheimer’s disease, but we know surprisingly little about its normal function in the CNS. Here, we show that this protease is critically involved in semaphorin 3A (Sema3A)-mediated axonal guidance processes in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4de27001cd6f1fbb44c4a4e83bb4e82a
http://europepmc.org/articles/PMC4820248
http://europepmc.org/articles/PMC4820248
Autor:
Bart De Strooper, Xavier Bossuyt, Tine Vanhoutvin, Anne-Catherine Vijverman, Fred Van Leuven, David Demedts, Rik Vandenberghe, Soraia Barão Lourenco Barao, Katarzyna Adamczuk, Lujia Zhou
Publikováno v:
ResearcherID
Previous studies have investigated the activity and protein levels of BACE1, the β-secretase, in the brain and cerebrospinal fluid (CSF) of Alzheimer's disease (AD) patients, however, results remain contradictory. We present here a highly specific a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7382eecf3589d021f03cc7567a07953
https://doi.org/10.2174/15672050113109990138
https://doi.org/10.2174/15672050113109990138
Autor:
Mathias Laga, Kris Gevaer, Diederik Moechars, M. Borgers, Katrijn Bockstael, Harry Gijsen, Bart De Strooper, Soraia Barão Lourenco Barao, Lujia Zhou, Wim Annaert, Marc Mercken
Publikováno v:
Journal of Biological Chemistry. 287:33719
The β-site amyloid precursor protein-cleaving enzyme BACE1 is a prime drug target for Alzheimer disease. However, the function and the physiological substrates of BACE1 remain largely unknown. In this work, we took a quantitative proteomic approach
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd1bba6ae2fef53afb0d6ffb68a6cc8e
https://doi.org/10.1074/jbc.a112.377465
https://doi.org/10.1074/jbc.a112.377465