Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Sora Yoon"'
Publikováno v:
Heliyon, Vol 10, Iss 4, Pp e25984- (2024)
Various studies have investigated the presence of microplastics (MPs) in food and their potential hazardous impact on human health. The frequency of human exposure to MPs, particularly through the consumption of manufactured food and drinking water,
Externí odkaz:
https://doaj.org/article/b36836b93ddc4242a5b0c01ec97c8711
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Integration of single-cell RNA sequencing data between different samples has been a major challenge for analyzing cell populations. Here the authors benchmark 46 workflows for differential expression analysis of single-cell data with multiple batches
Externí odkaz:
https://doaj.org/article/33e159f8ff6a4922aa21acf23a5db541
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Chromosome conformation capture techniques have recently revealed features beyond chromatin loops such as architectural stripes. Here the authors present their stripe detection tool ‘Stripenn’ to detect and quantitate stripes from any type of chr
Externí odkaz:
https://doaj.org/article/860621a9cb4d4e46b9f50ef3af2a03f5
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Meta-analyses increase statistical power by combining statistics from multiple studies. Meta-analysis methods have mostly been evaluated under the condition that all the data in each study have an association with the given phenotype. Howeve
Externí odkaz:
https://doaj.org/article/855cb6e277fa4760b73d3ae5f6fd7226
Autor:
Hye-Kyung Park, Nam Gu Yoon, Ji-Eun Lee, Sung Hu, Sora Yoon, So Yeon Kim, Jun-Hee Hong, Dougu Nam, Young Chan Chae, Jong Bae Park, Byoung Heon Kang
Publikováno v:
Experimental and Molecular Medicine, Vol 52, Iss 1, Pp 79-91 (2020)
Cancer therapeutics: Extending a drug’s reach A new drug that blocks heat shock proteins (HSPs), helper proteins that are co-opted by cancer cells to promote tumor growth, shows promise for cancer treatment. Several drugs have targeted HSPs, since
Externí odkaz:
https://doaj.org/article/35a514c7ab004b988412156186b7dc41
Publikováno v:
BMC Genomics, Vol 20, Iss 1, Pp 1-14 (2019)
Abstract Background Gene-set analysis (GSA) has been commonly used to identify significantly altered pathways or functions from omics data. However, GSA often yields a long list of gene-sets, necessitating efficient post-processing for improved inter
Externí odkaz:
https://doaj.org/article/2dbd651430df4e56aaa17669e8f4226f
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0232271 (2020)
Benchmarking RNA-seq differential expression analysis methods using spike-in and simulated RNA-seq data has often yielded inconsistent results. The spike-in data, which were generated from the same bulk RNA sample, only represent technical variabilit
Externí odkaz:
https://doaj.org/article/9c7bb2824caf4272a209149bd3fb087a
Autor:
Jae Min Lee, Sun Sil Choi, Yo Han Lee, Keon Woo Khim, Sora Yoon, Byung-gyu Kim, Dougu Nam, Pann-Ghill Suh, Kyungjae Myung, Jang Hyun Choi
Publikováno v:
Experimental and Molecular Medicine, Vol 50, Iss 10, Pp 1-11 (2018)
Metabolic disorders: TRIM-ming the fat A protein that targets peroxisome proliferator-activated receptor γ (PPARγ) (a key regulator of fat cell formation) for degradation suppresses the formation of fat. Excess fat can lead to obesity and cause typ
Externí odkaz:
https://doaj.org/article/c68173b575074c6487af109fa6f21442
Publikováno v:
BMC Genomics, Vol 18, Iss 1, Pp 1-11 (2017)
Abstract Background In differential expression analysis of RNA-sequencing (RNA-seq) read count data for two sample groups, it is known that highly expressed genes (or longer genes) are more likely to be differentially expressed which is called read c
Externí odkaz:
https://doaj.org/article/4b5d2da50d744c7bad16ef3c30bdbdc1
Autor:
Keon Woo Khim, Sun Sil Choi, Hyun-Jun Jang, Yo Han Lee, Eujin Lee, Ji-Min Hyun, Hye-Jin Eom, Sora Yoon, Jeong-Won Choi, Tae-Eun Park, Dougu Nam, Jang Hyun Choi
Publikováno v:
Cells, Vol 9, Iss 2, p 343 (2020)
Peroxisome proliferator-activated receptor γ (PPARγ) is a master regulator of adipose tissue biology. In obesity, phosphorylation of PPARγ at Ser273 (pSer273) by cyclin-dependent kinase 5 (CDK5)/extracellular signal-regulated kinase (ERK) orchestr
Externí odkaz:
https://doaj.org/article/a198bc4de1234390b827a6c4f2a6e969