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Publikováno v:
Journal of toxicology and environmental health. Part A. 81(12)
Humans possess three cytochrome P450 enzymes in the 2A subfamily (2A6, 2A7, and 2A13). P450 2A13 is mainly expressed in the human trachea and lung, whereas P450 2A6 is found in human liver. The P450 2A13 enzyme may be considered as the primary enzyme
Autor:
Tsutomu Shimada, Donghak Kim, Norie Murayama, Young-Ran Lim, Hiroshi Yamazaki, Kensaku Kakimoto, Masayuki Komori, Shigeo Takenaka, Sora Yeom, F. Peter Guengerich
1. 1-Chloropyrene, one of the major chlorinated polycyclic aromatic hydrocarbon contaminants, was incubated with human cytochrome P450 (P450 or CYP) enzymes including CYP1A1, 1A2, 1B1, 2A6, 2A13, 2B6, 2C9, 2D6, 2E1, 3A4 and 3A5. Catalytic differences
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d95726c696669b92064160997f6889c6