Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Sophina Ji"'
Autor:
Kian Huat Lim, Zhou Han, Hyun Yong Jeon, Jacob Kach, Enxuan Jing, Sebastien Weyn-Vanhentenryck, Mikaela Downs, Anna Corrionero, Raymond Oh, Juergen Scharner, Aditya Venkatesh, Sophina Ji, Gene Liau, Barry Ticho, Huw Nash, Isabel Aznarez
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Restoration of normal gene expression is one way to treat monogenic disorders. Here the authors target naturally occurring non-productive alternative splicing using antisense oligonucleotides to promote the production of functional proteins.
Externí odkaz:
https://doaj.org/article/b4b17242c1b24dc9905cc03dd97077f2
Autor:
Huw M. Nash, Barry Ticho, Juergen Scharner, Mikaela Downs, Hyun Yong Jeon, Sebastien M. Weyn-Vanhentenryck, Sophina Ji, Anna Corrionero, Isabel Aznarez, Enxuan Jing, Kian-Huat Lim, Jacob Kach, Aditya Venkatesh, Zhou Han, Raymond S Oh, Gene Liau
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nature Communications
Nature Communications
While most monogenic diseases are caused by loss or reduction of protein function, the need for technologies that can selectively increase levels of protein in native tissues remains. Here we demonstrate that antisense-mediated modulation of pre-mRNA
Autor:
Qian Lin, Zhou Han, Lori L. Isom, Charles Anumonwo, Meena, Isabel Aznarez, Anne Christiansen, Gene Liau, Chunling Chen, Sophina Ji, Steven C. Leiser, Chante Liu
Publikováno v:
Science Translational Medicine. 12
Dravet syndrome (DS) is an intractable developmental and epileptic encephalopathy caused largely by de novo variants in the SCN1A gene, resulting in haploinsufficiency of the voltage-gated sodium channel α subunit NaV1.1. Here, we used Targeted Augm
Autor:
Zhou, Han, Chunling, Chen, Anne, Christiansen, Sophina, Ji, Qian, Lin, Charles, Anumonwo, Chante, Liu, Steven C, Leiser, Meena, Isabel, Aznarez, Gene, Liau, Lori L, Isom
Publikováno v:
Science translational medicine. 12(558)
Dravet syndrome (DS) is an intractable developmental and epileptic encephalopathy caused largely by de novo variants in the
Autor:
Kelsey Derricks, Cheryl Chi, Matthew A. Nugent, Sophina Ji, Albert Lee, Vickery Trinkaus-Randall, Martin Minns
Publikováno v:
American journal of physiology. Cell physiology. 306(10)
The process of wound healing must be tightly regulated to achieve successful restoration of injured tissue. Previously, we demonstrated that when corneal epithelium is injured, nucleotides and neuronal factors are released to the extracellular milieu
Autor:
Albert Lee, Derricks, Kelsey, Minns, Martin, Sophina Ji, Cheryl Chi, Nugent, Matthew A., Trinkaus-Randall, Vickery
Publikováno v:
American Journal of Physiology: Cell Physiology; May2014, Vol. 306 Issue 10, pC972-C985, 14p