Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Sophie V Pageon"'
Autor:
Jorge Luis Galeano Niño, Sophie V Pageon, Szun S Tay, Feyza Colakoglu, Daryan Kempe, Jack Hywood, Jessica K Mazalo, James Cremasco, Matt A Govendir, Laura F Dagley, Kenneth Hsu, Simone Rizzetto, Jerzy Zieba, Gregory Rice, Victoria Prior, Geraldine M O'Neill, Richard J Williams, David R Nisbet, Belinda Kramer, Andrew I Webb, Fabio Luciani, Mark N Read, Maté Biro
Publikováno v:
eLife, Vol 9 (2020)
Cytotoxic T lymphocytes (CTLs) are thought to arrive at target sites either via random search or following signals by other leukocytes. Here, we reveal independent emergent behaviour in CTL populations attacking tumour masses. Primary murine CTLs coo
Externí odkaz:
https://doaj.org/article/d671480f3ae34c5f99f6cf4e7a7c2792
Autor:
Yuanqing Ma, Elvis Pandzic, Philip R. Nicovich, Yui Yamamoto, Joanna Kwiatek, Sophie V. Pageon, Aleš Benda, Jérémie Rossy, Katharina Gaus
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Cellular signalling is often facilitated by membrane protein clustering, but detection of protein clustering at high spatiotemporal resolution is challenging. Here the authors develop a single-chain FRET sensor they name CliF to look at intermolecula
Externí odkaz:
https://doaj.org/article/0214fa95f1064f5c88b533788fa353df
Publikováno v:
J R Soc Interface
Swarming has been observed in various biological systems from collective animal movements to immune cells. In the cellular context, swarming is driven by the secretion of chemotactic factors. Despite the critical role of chemotactic swarming, few met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47d61953c9c734e18196cc000c3eb0c8
https://doi.org/10.1098/rsif.2020.0879
https://doi.org/10.1098/rsif.2020.0879
Autor:
Laura F. Dagley, Matt A Govendir, Jorge Luis Galeano Niño, Maté Biro, Simone Rizzetto, Kenneth Hsu, David R. Nisbet, Richard J. Williams, Gregory Rice, Feyza Colakoglu, Fabio Luciani, Daryan Kempe, Sophie V. Pageon, James Cremasco, Andrew I. Webb, Belinda Kramer, Jerzy Zieba, Victoria Prior, Geraldine M. O'Neill, Jessica K Mazalo, Szun S. Tay, Mark Read, Jack D Hywood
Publikováno v:
eLife
eLife, Vol 9 (2020)
eLife, Vol 9 (2020)
Cytotoxic T lymphocytes (CTLs) are thought to arrive at target sites either via random search or following signals by other leukocytes. Here, we reveal independent emergent behaviour in CTL populations attacking tumour masses. Primary murine CTLs coo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eb2afde118dab5836e3eaf95a1491aa
https://doi.org/10.7554/elife.56554
https://doi.org/10.7554/elife.56554
Autor:
Daryan Kempe, Jessica K Mazalo, Richard J. Williams, Gregory Rice, Jorge Luis Galeano Niño, Fabio Luciani, Jerzy Zieba, Geraldine M. O'Neill, Simone Rizzetto, David R. Nisbet, Belinda Kramer, Andrew I. Webb, Victoria Prior, Jack D Hywood, Szun S. Tay, Mark Read, Feyza Colakoglu, Maté Biro, James Cremasco, Laura F. Dagley, Matt A Govendir, Sophie V. Pageon, Kenneth Hsu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2f720c336de28da577b6a7db47b8156
https://doi.org/10.7554/elife.56554.sa2
https://doi.org/10.7554/elife.56554.sa2
Publikováno v:
Molecular Biology of the Cell
Immune cell recognition of antigens is a pivotal process in initiating immune responses against injury, pathogens, and cancers. Breakthroughs over the past decade support a major role for mechanical forces in immune responses, laying the foundation f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3fc87ab439e6ef6b2d9e4d4fc924edb
https://doi.org/10.1091/mbc.e18-02-0120
https://doi.org/10.1091/mbc.e18-02-0120
Autor:
Philip R. Nicovich, Joanna M. Kwiatek, Jérémie Rossy, Elvis Pandzic, Katharina Gaus, Yuanqing Ma, Yui Yamamoto, Sophie V. Pageon, Aleš Benda
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Nature Communications
Nature Communications
Clustering of the T-cell receptor (TCR) is thought to initiate downstream signalling. However, the detection of protein clustering with high spatial and temporal resolution remains challenging. Here we establish a Förster resonance energy transfer (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f69c74a6fed8523c74539049f67b3f7
https://doaj.org/article/0214fa95f1064f5c88b533788fa353df
https://doaj.org/article/0214fa95f1064f5c88b533788fa353df
Autor:
Andrew K. Sewell, Katharina Gaus, Thibault Tabarin, Oreste Acuto, John S. Bridgeman, David Price, Yijun Gao, Yuanqing Ma, Andre Cohnen, Jamie Rossjohn, J. Justin Gooding, Carola Benzing, Sophie V. Pageon, Michael D. Crowther, Garry Dolton, Robert G. Parton, Philip R. Nicovich, Yui Yamamoto, Jérémie Rossy, Katie Tungatt
Publikováno v:
Proceedings of the National Academy of Sciences. 113
T-cell activation requires the translation of antigen binding to the T-cell receptor (TCR) into intracellular signaling. However, how antigen recognition and signal transduction are mechanistically linked is poorly understood. Here, we used single-mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20f3a31b3933110ba9a548d526531747
https://doi.org/10.1073/pnas.1615763113
https://doi.org/10.1073/pnas.1615763113
Autor:
Katie Tungatt, Michael D. Crowther, Yuanqing Ma, David Price, Yui Yamamoto, Oreste Acuto, Yijun Gao, Carola Benzing, J. Justin Gooding, Andre Cohnen, John S. Bridgeman, Garry Dolton, Andrew K. Sewell, Jérémie Rossy, Jamie Rossjohn, Thibault Tabarin, Sophie V. Pageon, Katharina Gaus, Robert G. Parton
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 113(37)
Antigen recognition by the T-cell receptor (TCR) is a hallmark of the adaptive immune system. When the TCR engages a peptide bound to the restricting major histocompatibility complex molecule (pMHC), it transmits a signal via the associated CD3 compl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::842879044925837f569b381c0f5677ee
https://pubmed.ncbi.nlm.nih.gov/27791190
https://pubmed.ncbi.nlm.nih.gov/27791190
Publikováno v:
Molecular Biology of the Cell
Despite the increasingly widespread use of single-molecule localization microscopy (SMLM) in biology, the extent to which the spatial organization of proteins influences signaling is not easy to quantify. Clus-DoC is a novel analysis method that comb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a808c8177c98b97d635113b56757dd6
https://pubmed.ncbi.nlm.nih.gov/27582387
https://pubmed.ncbi.nlm.nih.gov/27582387