Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Sophie T. Williams"'
Autor:
Hannah Gagg, Greg Wells, Sarah J. Danson, Spencer J. Collis, Juha Rantala, Ola Rominiyi, Callum Jones, Thomas Helleday, Katie N. Myers, Connor McGarrity-Cottrell, Sophie T. Williams, Samantha Conroy
Publikováno v:
F1000Research, Vol 12 (2024)
With diminishing returns and high clinical failure rates from traditional preclinical and animal-based drug discovery strategies, more emphasis is being placed on alternative drug discovery platforms. Ex vivo approaches represent a departure from bot
Externí odkaz:
https://doaj.org/article/0d07e3d1808746329649b8bab6580273
Autor:
Hannah Gagg, Greg Wells, Sarah J. Danson, Spencer J. Collis, Juha Rantala, Ola Rominiyi, Callum Jones, Thomas Helleday, Katie N. Myers, Connor McGarrity-Cottrell, Sophie T. Williams, Samantha Conroy
Publikováno v:
F1000Research, Vol 12 (2023)
With diminishing returns and high clinical failure rates from traditional preclinical and animal-based drug discovery strategies, more emphasis is being placed on alternative drug discovery platforms. Ex vivo approaches represent a departure from bot
Externí odkaz:
https://doaj.org/article/563d9cb96d614270ab9d4531c06cee5a
Autor:
Haonan Lu, Mubarik Arshad, Andrew Thornton, Giacomo Avesani, Paula Cunnea, Ed Curry, Fahdi Kanavati, Jack Liang, Katherine Nixon, Sophie T. Williams, Mona Ali Hassan, David D. L. Bowtell, Hani Gabra, Christina Fotopoulou, Andrea Rockall, Eric O. Aboagye
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Radiomics—the quantification of features within tumor images—has shown prognostic potential in cancer. Here, the authors use a machine learning approach to develop a radiomic-based small set of descriptors to predict ovarian cancer patient surviv
Externí odkaz:
https://doaj.org/article/7fff94167bb54d9d9ccc2351fa73055a
Autor:
Oliver Burton, Julie Woodfield, Daniel Richardson, Giles Critchley, Angelos Kolias, Thomas Santarius, Lewis Thorne, Peter Whitfield, Ola Rominiyi, Bharti Kewlani, Harsh Bhatt, Ahmed Ahmed, Michael O’Sullivan, Rasheed Zakaria, Michael D Jenkinson, Gerard Thompson, Paul M Brennan, Rory Piper, Seong Hoon Lee, Neil Barua, Engelbert Mthunzi, Sara Venturini, Daniel M Fountain, Najma Ahmed, Stephen J Price, Colin Watts, Michael T C Poon, Stuart Smith, Anand Pandit, Ryan K Mathew, Soham Bandyopadhyay, Rosa Sun, Setthasorn Zhi Yang Ooi, Victoria Wykes, William Bolton, Abdullah Egiz, Samantha J Mills, Babar Vaqas, Natalie Simon, Puneet Plaha, Georgios Solomou, Aswin Chari, Grainne McKenna, Melissa Gough, Simon Lammy, Sophie T Williams, Isabelle Williams, Andrew J Martin, Sam Hodgson, Robert Spencer, Adam Waldman, Armin Nazari, Joshua Erhabor, Omar Salim, Saad Moughal, Chinedu Brian Egu, Abdurrahman I Islim, Christopher P Millward, Suhaib Abualsaud, Michael Amoo, Neeraj Kalra, Agbolahan Sofela, Thomas C Booth, George E Richardson, Conor S Gillespie, Orla Mantle, Abigail Clynch, Jay J Park, Emily R Bligh, Avani Shanbhag, Moritz Steinruecke, Alvaro Yanez Touzet, Hannah Redpath, Gideon Adegboyega, Prithvi Bahu, Rosaline de Koning, Tomas Ferreira, Dana Hutton, Jashan Selvakumar, Tiffany TS Ye, Ashvin Kuri, Robin Borchert, Bea Duric, Elena Roman, Kristy Kehoe, Jeremy Cheong, Lauren Harris, Mohammad A Mustafa, Hidayatul Abdullmalek, Chinelo Afulukwe, Abdelsalam Nedal Al-Sousi, Yahia Al-Tamimi, Ajitesh Anand, Peter Bodkin, Ion Boiangiu, Abbey Boyle, Christiaan Bredell, Talhah Chaudri, Ana Cios, Iona Cleer, David Coope, Ian Coulter, Harriet Davis, Paolo Jose De Luna, Nayan Dey, Justyna O Ekert, Jinendra Ekanayake, Anna Elso, Tom Flannery, Kwan Wai Fung, Rahul Ganguly, Sanay Goyal, Emily Hardman, Theodore Hirst, Kelvin Sunn Hoah, Kismet Hossain-Ibrahim, Lena Mary Houlihan, Sami Squali Houssaini, Sadid Hoque, Mahnoor Javed, Siddarth Kannan, Efthymia Maria Kapasouri, Andrew Keenlyside, Prerna Khanna, Kunalika Sathish Kumar, Eunkyung Lee, Robert Magouirk, Riccardo Masina, Adele Mazzoleni, Patrick McAleavey, Daniel McSweeney, Trinh Ton Nu Ngoc, Shiva A Nischal, Jonathan Pesic-Smith, Peter Peterson, Isaac Phang, Shyam Pujara, Marwa Mohammed Elrasheed Saad, Shinjan Sangal, Veekshith Shetty, Irtiza Syed, Jesvin Tom Sunny, Anca-Mihaela Vasilica, Daniel O’Flaherty, Arslan Khaliq Raja, Daniele Ramsay, Renitha Reddi, Dorina Roy, Jeremiah Samkutty, Edward Jerome St George, Preethi Subramanian, Vaibhav Sundaresan, Kieron Sweeney, Boon Hoe Tan, Nicole Turnbull, Yuewei Tao, Rebecca Tweedie, Anastasia Tzatzidou, Kathrin Whitehouse, Jack Wildman, Karl Williams, Kelvin Sunn Yap, Mahir Yousuff, Asaad Zulfiqar, Sophie Camp, Setthasorn ZY Ooi
Publikováno v:
BMJ Open, Vol 12, Iss 9 (2022)
Introduction Glioblastoma is the most common malignant primary brain tumour with a median overall survival of 12–15 months (range 6–17 months), even with maximal treatment involving debulking neurosurgery and adjuvant concomitant chemoradiotherap
Externí odkaz:
https://doaj.org/article/ea5706fc5b024e75ade614ef75919d03
Autor:
Sophie T. Williams, Greg Wells, Samantha Conroy, Hannah Gagg, Richard Allen, Ola Rominiyi, Thomas Helleday, Katie Hullock, Catherine E. W. Pennington, Juha Rantala, Spencer J. Collis, Sarah J. Danson
Publikováno v:
Expert reviews in molecular medicine. 24
Despite advances in cancer genomics and the increased use of genomic medicine, metastatic cancer is still mostly an incurable and fatal disease. With diminishing returns from traditional drug discovery strategies, and high clinical failure rates, mor
Autor:
Conor S, Gillespie, Emily R, Bligh, Michael T C, Poon, Georgios, Solomou, Abdurrahman I, Islim, Mohammad A, Mustafa, Ola, Rominiyi, Sophie T, Williams, Neeraj, Kalra, Ryan K, Mathew, Thomas C, Booth, Gerard, Thompson, Paul M, Brennan, Michael D, Jenkinson, Orla, Mantle
Publikováno v:
Gillespie, C S, Bligh, E, Poon, M, Solomou, G, Islim, A I, Mustafa, M, Rominiyi, O, Williams, S, Kalra, N, Mathew, R K, Booth, T, Thompson, G, Brennan, P & Jenkinson, M D 2022, ' Imaging timing after glioblastoma surgery (INTERVAL-GB): protocol for a UK and Ireland, multicentre retrospective cohort study ', BMJ Open, vol. 12, no. 9, e063043 . https://doi.org/10.1136/bmjopen-2022-063043
IntroductionGlioblastoma is the most common malignant primary brain tumour with a median overall survival of 12–15 months (range 6–17 months), even with maximal treatment involving debulking neurosurgery and adjuvant concomitant chemoradiotherapy
Publikováno v:
European Geriatric Medicine. 11:63-70
Distress in delirium causes significant morbidity for patients and their relatives, but it remains under recognised. This review discusses the current literature regarding distress in delirium: its aetiology, available assessment tools and potential
Autor:
Anand Velusamy, Angela F. Brady, Joseph Carlow, Huw Dorkins, Rebecca Igbokwe, Benjamin Whitelaw, Teng-Teng Chung, Rachel Harrison, Fiona Lalloo, Paul Brennan, Louise Izatt, Schaida Schirwani, Alan Kelsall, Barbara McGowan, Sophie T Williams, Rosemarie Davidson, Paul V. Carroll, Nicola Tufton, Patrick J. Morrison, Soo-Mi Park, Christopher Bowles, John Newell-Price, Julian Adlard, Monika Kosicka-Slawinska, Eamonn R. Maher, Richard M. Martin, Lara Hawkes, Rebecca Dyer, Scott Akker, Rupert Obholzer, Florian Wernig, Tricia Tan, Ruth T Casey, Prodromos Chatzikyriakou, Gemma White, Anna L. Mitchell, Mary Porteous
Publikováno v:
Clinical endocrinologyREFERENCES. 96(4)
Objective Phaeochromocytomas and paragangliomas (PPGL) are rare, but strongly heritable tumours. Variants in succinate dehydrogenase (SDH) subunits are identified in approximately 25% of cases. However, clinical and genetic information of patients wi
Autor:
Sophie T. Williams, Sophie Camp, Lewis Thorne, Archie Hughes-Hallett, Dipankar Nandi, Hani J. Marcus
Publikováno v:
Neurosurgical Review. 40:621-631
The lack of a simple, objective and reproducible system to describe glioblastoma multiforme (GBM) represents a major limitation in comparative effectiveness research. The objectives of this study were therefore to develop such a grading system and to
Publikováno v:
European geriatric medicine. 11(1)
Delirium is a common clinical syndrome associated with increased physical and psychological morbidity, mortality, inpatient stay and healthcare costs. There is growing interest in understanding the delirium experience and its psychological impact, in