Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Sophie Saussenthaler"'
Autor:
Meriem Ouni, Fabian Eichelmann, Markus Jähnert, Christin Krause, Sophie Saussenthaler, Christiane Ott, Pascal Gottmann, Thilo Speckmann, Peter Huypens, Stefan Wolter, Oliver Mann, Martin Hrabé De Angelis, Johannes Beckers, Henriette Kirchner, Matthias B. Schulze, Annette Schürmann
Publikováno v:
Molecular Metabolism, Vol 75, Iss , Pp 101774- (2023)
Objectives: Better disease management can be achieved with earlier detection through robust, sensitive, and easily accessible biomarkers. The aim of the current study was to identify novel epigenetic biomarkers determining the risk of type 2 diabetes
Externí odkaz:
https://doaj.org/article/cbd304180aef4bbdad8c44ce9af6265c
Autor:
Pascal Gottmann, Meriem Ouni, Sophie Saussenthaler, Julian Roos, Laura Stirm, Markus Jähnert, Anne Kamitz, Nicole Hallahan, Wenke Jonas, Andreas Fritsche, Hans-Ulrich Häring, Harald Staiger, Matthias Blüher, Pamela Fischer-Posovszky, Heike Vogel, Annette Schürmann
Publikováno v:
Molecular Metabolism, Vol 11, Iss , Pp 145-159 (2018)
Objective: Obesity and type 2 diabetes (T2D) arise from the interplay between genetic, epigenetic, and environmental factors. The aim of this study was to combine bioinformatics and functional studies to identify miRNAs that contribute to obesity and
Externí odkaz:
https://doaj.org/article/b43f895593b3447b9e47be298c257584
Autor:
Christian Baumeier, Luisa Schlüter, Sophie Saussenthaler, Thomas Laeger, Maria Rödiger, Stella Amelie Alaze, Louise Fritsche, Hans-Ulrich Häring, Norbert Stefan, Andreas Fritsche, Robert Wolfgang Schwenk, Annette Schürmann
Publikováno v:
Molecular Metabolism, Vol 6, Iss 10, Pp 1254-1263 (2017)
Objective: Increased hepatic expression of dipeptidyl peptidase 4 (DPP4) is associated with non-alcoholic fatty liver disease (NAFLD). Whether this is causative for the development of NAFLD is not yet clarified. Here we investigate the effect of hepa
Externí odkaz:
https://doaj.org/article/7a5157955644472dab172f8d51f2cfa2
Autor:
Meriem Ouni, Fabian Eichelmann, Tina Rönn, Markus Jähnert, Pascal Gottmann, Lisa Zellner, Mandy Stadion, Sophie Saussenthaler, Clemens Wittenbecher, Annette Schürmann, Charlotte Ling, Matthias B. Schulze
Publikováno v:
Diabetes
The identification of individuals with a high risk of developing type 2 diabetes (T2D) is fundamental for prevention. Here, we used a translational approach and prediction criteria to identify changes in DNA methylation visible before the development
Autor:
Annette Schürmann, Matthias B. Schulze, Charlotte Ling, Pascal Gottmann, Lisa Zellner, Tina Rönn, Clemens Wittenbecher, Mandy Stadion, Markus Jähnert, Fabian Eichelmann, Sophie Saussenthaler, Meriem Ouni, Ada Admin
The identification of individuals with a high risk of developing type 2 diabetes (T2D) is fundamental for prevention. Here, we used a translational approach and prediction criteria to identify changes in DNA methylation visible before the developmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a9032a83ac1cde8c9e71b2517b6251a
https://doi.org/10.2337/figshare.12794957.v1
https://doi.org/10.2337/figshare.12794957.v1
Autor:
Thomas Laeger, Louise Fritsche, Christian Baumeier, Norbert Stefan, Annette Schürmann, Sophie Saussenthaler, Andreas Fritsche, Robert W. Schwenk, Maria Rödiger, Hans-Ulrich Häring, Luisa Schlüter, Stella Amelie Alaze
Publikováno v:
Molecular Metabolism
Mol. Metab. 6, 1254-1263 (2017)
Molecular Metabolism, Vol 6, Iss 10, Pp 1254-1263 (2017)
Mol. Metab. 6, 1254-1263 (2017)
Molecular Metabolism, Vol 6, Iss 10, Pp 1254-1263 (2017)
Objective Increased hepatic expression of dipeptidyl peptidase 4 (DPP4) is associated with non-alcoholic fatty liver disease (NAFLD). Whether this is causative for the development of NAFLD is not yet clarified. Here we investigate the effect of hepat
Autor:
Violeta Raverdy, Charlotte Ling, Sophie Saussenthaler, Markus Jähnert, Philippe Froguel, A Kammel, Stéphane Lobbens, Annette Schürmann, Robert Caiazzo, Deike Hesse, François Pattou, Robert W. Schwenk, Jussi Pihlajamäki, Christian Baumeier, Mickaël Canouil, Emma Nilsson, Luisa Schlüter
Publikováno v:
Diabetes. 66:25-35
Hepatic DPP4 expression is elevated in subjects with ectopic fat accumulation in the liver. However, whether increased dipeptidyl peptidase 4 (DPP4) is involved in the pathogenesis or is rather a consequence of metabolic disease is not known. We ther
Autor:
Annette Schürmann, Sophie Saussenthaler, Kristin Schwerbel, Pascal Gottmann, Thomas Laeger, Meriem Ouni, Sabrina Christmann, Christian Baumeier
Publikováno v:
The Journal of nutritional biochemistry. 63
Dipeptidyl peptidase 4 (DPP4) is known to be elevated in metabolic disturbances such as obesity, type 2 diabetes and fatty liver disease. Lowering DPP4 concentration by pharmacological inhibition improves glucose homeostasis and exhibits beneficial e
Autor:
Heike Vogel, Pamela Fischer-Posovszky, A Kamitz, Nicole Hallahan, Annette Schürmann, Wenke Jonas, Sophie Saussenthaler, Julian Roos, Markus Jähnert, Laura Stirm, Matthias Blüher, Pascal Gottmann, Andreas Fritsche, Harald Staiger, Hans-Ulrich Häring, Meriem Ouni
Publikováno v:
Mol. Metab. 11, 145-159 (2018)
Molecular Metabolism
Molecular Metabolism, Vol 11, Iss, Pp 145-159 (2018)
Molecular Metabolism
Molecular Metabolism, Vol 11, Iss, Pp 145-159 (2018)
Objective Obesity and type 2 diabetes (T2D) arise from the interplay between genetic, epigenetic, and environmental factors. The aim of this study was to combine bioinformatics and functional studies to identify miRNAs that contribute to obesity and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa18dd1e272039aa7e70918e2354e9f5
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=53354
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=53354
Autor:
Sara Schumann, Susanne Klaus, Juliane Kasch, Jaap Keijer, Evert M. van Schothorst, Sophie Saussenthaler, Isabel Kanzleiter, Annette Schürmann
Publikováno v:
Journal of Nutritional Biochemistry, 57, 86-92
Journal of Nutritional Biochemistry 57 (2018)
Journal of Nutritional Biochemistry 57 (2018)
Perinatal maternal high-fat consumption is known to increase the obesity and type 2 diabetes susceptibility and to impair exercise performance in the offspring. We hypothesize that epigenetic modifications in the skeletal muscle are partly responsibl