Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Sophie Sarret"'
Autor:
Thomas Hoyler, Bettina Bannert, Cédric André, Damian Beck, Thomas Boulay, David Buffet, Nadja Caesar, Thomas Calzascia, Janet Dawson, Diego Kyburz, Robert Hennze, Christine Huppertz, Amanda Littlewood-Evans, Pius Loetscher, Kirsten D. Mertz, Satoru Niwa, Gautier Robert, James S. Rush, Giulia Ruzzante, Sophie Sarret, Thomas Stein, Ismahane Touil, Grazyna Wieczorek, Geraldine Zipfel, Stuart Hawtin, Tobias Junt
Publikováno v:
JCI Insight, Vol 7, Iss 13 (2022)
IL-1 receptor-activated kinase 1 (IRAK1) is involved in signal transduction downstream of many TLRs and the IL-1R. Its potential as a drug target for chronic inflammatory diseases is underappreciated. To study its functional role in joint inflammatio
Externí odkaz:
https://doaj.org/article/6fc6e2c6d008483f99d660e2370be0ce
Autor:
Mohamed Bentires-Alj, Debora Bonenfant, Hans Voshol, Sophie Sarret, Stephan Duss, Nicola Aceto, Nina Sausgruber, Abdullah Alajati
PDF file, 104K, List of peptides differentially phosphorylated in MCF10A-Delta-HER2 cells compared to WT-HER2.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::709ddb447a8799bd5591f6df567344a2
https://doi.org/10.1158/0008-5472.22397700.v1
https://doi.org/10.1158/0008-5472.22397700.v1
Autor:
Mohamed Bentires-Alj, Debora Bonenfant, Hans Voshol, Sophie Sarret, Stephan Duss, Nicola Aceto, Nina Sausgruber, Abdullah Alajati
PDF file, 246K, Quantification of WT-HER2 or Delta-HER2 and their effect on wound healing (S1); Low level expression of Delta-HER2 induces P-ERK and P-AKT, increases migration and induces mammary tumors (S2); Effect of WT-HER2 and Delta-HER2 expressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e9e762a05dca7d1a9fe2eae5c2f2a30
https://doi.org/10.1158/0008-5472.22397703.v1
https://doi.org/10.1158/0008-5472.22397703.v1
Autor:
Mohamed Bentires-Alj, Debora Bonenfant, Hans Voshol, Sophie Sarret, Stephan Duss, Nicola Aceto, Nina Sausgruber, Abdullah Alajati
PDF file, 66K, WT-HER2 or Delta-HER2 revealed a specific set of genes that were upregulated in MCF10A-Delta-HER2 cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a96d52d0c84e67f96f56bc81fbe1fa09
https://doi.org/10.1158/0008-5472.22397697
https://doi.org/10.1158/0008-5472.22397697
Autor:
Amanda Littlewood-Evans, Sophie Sarret, Frédéric Bornancin, Yeter Kolb, Isabelle Isnardi, Jean Quancard, Grazyna Wieczorek, Hans-Guenter Zerwes, Achim Schlapbach, Ratiba Touil, Nadja Caesar, Stephanie Valeaux, Karen Beltz, Thomas Le Meur, Maureen Bardet, Christian Beerli, Jiri Kovarik, Tobias Junt, Thomas Calzascia, Kea Martin, Catherine H. Régnier, Marc Bigaud, Laura Israel, Grozdan Cvijetic, Elena Degl'Innocenti
Publikováno v:
Arthritis & Rheumatology. 72:919-930
Objective Fcγ receptors (FcγR) play important roles in both protective and pathogenic immune responses. The assembly of the CBM signalosome encompassing caspase recruitment domain-containing protein 9, B cell CLL/lymphoma 10, and mucosa-associated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d875d2102180de2a6699c3ac5aa48f6
https://doi.org/10.1002/art.41204
https://doi.org/10.1002/art.41204
Autor:
Amanda Littlewood-Evans, Joschka Willemsen, Thomas Hoyler, Marie-Therese Neuhoff, Clemence Tessier, Juan Zhang, Tara N. Thorsen, Maroof Hasan, Sophie Sarret, James S. Rush, Richard M. Siegel, Emma Noir, Danilo Guerini
Publikováno v:
Cell reports. 37(6)
Tumor necrosis factor (TNF) is a key driver of several inflammatory diseases, such as rheumatoid arthritis, inflammatory bowel disease, and psoriasis, in which affected tissues show an interferon-stimulated gene signature. Here, we demonstrate that T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4f390fc90121d892f5efbd86eac953e
https://pubmed.ncbi.nlm.nih.gov/34758308
https://pubmed.ncbi.nlm.nih.gov/34758308
Autor:
Stephanie Valeaux, Juan Zhang, Rainer Kneuer, Janet Dawson, Saijel Patel, Tina Rubic-Schneider, Tobias Junt, Perrine Loesle, Sophie Sarret, Nina Gommermann, Bruno Tigani, José M. Carballido, Verena Apfel, Amanda Littlewood-Evans, Alban Muller
Publikováno v:
The Journal of Experimental Medicine
Littlewood-Evans et al. demonstrate that extracellular succinate leads to the propagation of inflammatory macrophage activation, providing translational evidence to support the development of GPR91 antagonists for the treatment of rheumatoid arthriti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8e29df82da3188d4f888540015f1c86
https://doi.org/10.1084/jem.20160061
https://doi.org/10.1084/jem.20160061
Autor:
Mohamed Bentires-Alj, Stephan Duss, Abdullah Alajati, Hans Voshol, Nina Sausgruber, Debora Bonenfant, Sophie Sarret, Nicola Aceto
Publikováno v:
Cancer research
The HER2 gene is amplified and overexpressed in approximately 20% of invasive breast cancers where it is associated with metastasis and poor prognosis. Here, we describe a constitutively active splice variant of HER2 (Delta-HER2) in human mammary epi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05fd927471f2271a283dbfa3b7d17fd1
https://pubmed.ncbi.nlm.nih.gov/23867476
https://pubmed.ncbi.nlm.nih.gov/23867476