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pro vyhledávání: '"Sophie Roigas"'
Autor:
Sophie Roigas, Kumar R. Kakularam, Michael Rothe, Dagmar Heydeck, Polamarasetty Aparoy, Hartmut Kuhn
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 18, p 14154 (2023)
The human genome involves six functional arachidonic acid lipoxygenase (ALOX) genes and the corresponding enzymes (ALOX15, ALOX15B, ALOX12, ALOX12B, ALOXE3, ALOX5) have been implicated in cell differentiation and in the pathogenesis of inflammatory,
Externí odkaz:
https://doaj.org/article/e72034ee2d2341fdb90dd246eeebf133
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 24, p 16026 (2022)
Eicosanoids and related compounds are pleiotropic lipid mediators, which are biosynthesized in mammals via three distinct metabolic pathways (cyclooxygenase pathway, lipoxygenase pathway, epoxygenase pathway). These mediators have been implicated in
Externí odkaz:
https://doaj.org/article/3c4c11052e5d4c5b9dab5ebe3fd1a637
Publikováno v:
Progress in Lipid Research. 72:55-74
The reaction specificity of lipoxygenases (ALOX) impacts the biological activity of these enzymes and also constitutes the decisive parameter for enzyme classification. ALOX15 orthologs, commonly known as 12/15-lipoxygenases, have recently been sugge