Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Sophie Redon"'
Publikováno v:
Cell Reports, Vol 17, Iss 12, Pp 3107-3114 (2016)
Oxidative damage of telomeres can promote cancer, cardiac failure, and muscular dystrophy. Specific mechanisms protecting telomeres from oxidative damage have not been described. We analyzed telomeric chromatin composition during the cell cycle and s
Externí odkaz:
https://doaj.org/article/07e78fbb34ed483da8e2ec822ce90354
Publikováno v:
Cell Reports, Vol 17, Iss 12, Pp 3107-3114 (2016)
Cell reports
Cell reports
Summary Oxidative damage of telomeres can promote cancer, cardiac failure, and muscular dystrophy. Specific mechanisms protecting telomeres from oxidative damage have not been described. We analyzed telomeric chromatin composition during the cell cyc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5c06b2e058ee07d4164d21b3ac0fac4
http://www.sciencedirect.com/science/article/pii/S221112471631645X
http://www.sciencedirect.com/science/article/pii/S221112471631645X
Publikováno v:
Nucleic Acids Research
NUCLEIC ACIDS RESEARCH
NUCLEIC ACIDS RESEARCH
Telomeres, the physical ends of eukaryotic chromosomes, are transcribed into telomeric repeat-containing RNA (TERRA), a large non-coding RNA, which forms an integral part of telomeric heterochromatin. In vitro, naked TERRA molecules are efficient inh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::957db9dd7dc933e80e703e3ba21d5837
http://doc.rero.ch/record/302688/files/gkt695.pdf
http://doc.rero.ch/record/302688/files/gkt695.pdf
Publikováno v:
Methods (San Diego Calif.)
The ends of eukaryotic chromosomes, known as telomeres, consist of repetitive DNA sequences, multiple proteins and noncoding RNAs. Telomeres are dynamic structures that play crucial roles as guardians of genome stability and tumor suppressors. Defect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d22abb4cfa3b1e15558fc0a3041c8c5
https://pubmed.ncbi.nlm.nih.gov/27520492
https://pubmed.ncbi.nlm.nih.gov/27520492
Autor:
Christina Raftopoulou, Raghav Chawla, Harry Wischnewski, Claus M. Azzalin, Sophie Redon, Sarantis Gagos
Publikováno v:
The EMBO Journal. 30:4047-4058
Eukaryotic up-frameshift 1 (UPF1) is a nucleic acid-dependent ATPase and 5′-to-3′ helicase, best characterized for its roles in cytoplasmic RNA quality control. We previously demonstrated that human UPF1 binds to telomeres in vivo and its depleti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0651509ccf4bcad1d717b9b9bddf12d
https://doi.org/10.1038/emboj.2011.280
https://doi.org/10.1038/emboj.2011.280
Autor:
Raghav, Chawla, Sophie, Redon, Christina, Raftopoulou, Harry, Wischnewski, Sarantis, Gagos, Claus M, Azzalin
Publikováno v:
The EMBO journal
The EMBO Journal
The EMBO Journal
Eukaryotic up-frameshift 1 (UPF1) is a nucleic acid-dependent ATPase and 5'-to-3' helicase, best characterized for its roles in cytoplasmic RNA quality control. We previously demonstrated that human UPF1 binds to telomeres in vivo and its depletion l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::c90a1fc519d0e408dadc772ee6fcff09
Publikováno v:
Molecular Cell. 32:465-477
Vertebrate telomeres are transcribed into telomeric repeat-containing RNA (TERRA) that associates with telomeres and may be important for telomere function. Here, we demonstrate that telomeres are also transcribed in Saccharomyces cerevisiae by RNA p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b837452c61d72a956a13588d60df4621
https://doi.org/10.1016/j.molcel.2008.10.019
https://doi.org/10.1016/j.molcel.2008.10.019
Protein–RNA and protein–protein interactions mediate association of human EST1A/SMG6 with telomerase
Publikováno v:
Nucleic Acids Research
The human EST1A/SMG6 polypeptide physically interacts with the chromosome end replication enzyme telomerase. In an attempt to better understand hEST1A function, we have started to dissect the molecular interactions between hEST1A and telomerase. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::949f98644e61626432df81eb9056b5c8
https://doi.org/10.1093/nar/gkm724
https://doi.org/10.1093/nar/gkm724
Publikováno v:
The Journal of Organic Chemistry. 68:7004-7008
The electrophilic ipso-reactions of a tBu-calix[6]arene that presents alternate O-methyl and O-2-methylen-N-methyl-imidazolyl groups (1) at the small rim have been studied. Whereas 1 underwent per-sulfonation in sulfuric acid, it selectively reacted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8ac7530568602feeffa2f1dce6b89aa
https://doi.org/10.1021/jo034557j
https://doi.org/10.1021/jo034557j
Publikováno v:
Biochemistry. 40:8463-8470
The telomeric sequence (T(2)G(4))(4) was platinated in aqueous solutions containing 50 mM LiClO(4), NaClO(4), or KClO(4). The identification of the guanines which reacted with [Pt(NH(3))(3)(H(2)O)](2+) revealed that the same type of folding exists in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4545142008b64629db418fc3e421d886
https://doi.org/10.1021/bi001565a
https://doi.org/10.1021/bi001565a