Biallelic non-productive enhancer-promoter interactions precede imprinted expression of Kcnk9 during mouse neural commitment

Autor: Cecilia Rengifo Rojas, Jil Cercy, Sophie Perillous, Céline Gonthier-Guéret, Bertille Montibus, Stéphanie Maupetit-Méhouas, Astrid Espinadel, Marylou Dupré, Charles C. Hong, Kenichiro Hata, Kazuhiko Nakabayashi, Antonius Plagge, Tristan Bouschet, Philippe Arnaud, Isabelle Vaillant, Franck Court

Publikováno v: HGG Advances, Vol 5, Iss 2, Pp 100271- (2024)

Summary: It is only partially understood how constitutive allelic methylation at imprinting control regions (ICRs) interacts with other regulation levels to drive timely parental allele-specific expression along large imprinted domains. The Peg13-Kcn

Externí odkaz: https://doaj.org/article/d7cbd17169d146879f77c972bc9cd96b

Genome-Wide Prediction of Functional Gene-Gene Interactions Inferred from Patterns of Genetic Differentiation in Mice and Men

Autor: Sophie Perillous, David Sondervan, Zoltán Bochdanovits, Peter Heutink, Dorret I. Boomsma, Toos C. E. M. van Beijsterveldt

Publikováno v: Bochdanovits, Z, Sondervan, D, Perillous, S, van Beijsterveldt, C E M, Boomsma, D I & Heutink, P 2008, ' Genome-Wide Prediction of Functional Gene-Gene Interactions Inferred from Patterns of Genetic Differentiation in Mice and Men. ', PLoS ONE, vol. 3, no. 2, e1593 . https://doi.org/10.1371/journal.pone.0001593
PLoS ONE, 3(2):e1593. Public Library of Science
PLoS ONE, Vol 3, Iss 2, p e1593 (2008)
PLoS ONE

The human genome encodes a limited number of genes yet contribute to individual differences in a vast array of heritable traits. A possible explanation for the capacity our genome to generate this virtually unlimited range of phenotypic variation in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d64ba90bc4168e37b0454444533d66e