Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Sophie P. Chung"'
Autor:
Cheng Chen, Sean Hennessy, Colleen M. Brensinger, Warren B. Bilker, Sascha Dublin, Sophie P. Chung, John R. Horn, Kacie F. Bogar, Charles E. Leonard
Publikováno v:
Clinical and Translational Science, Vol 16, Iss 2, Pp 326-337 (2023)
Abstract Antidepressants are associated with traumatic injury and are widely used with other medications. It remains unknown how drug–drug–drug interactions (3DIs) between antidepressants and two other drugs may impact potential injury risks asso
Externí odkaz:
https://doaj.org/article/2b2adebda87e4a949890c4d970be9f12
Autor:
Cheng Chen, Sean Hennessy, Colleen M. Brensinger, Emily K. Acton, Warren B. Bilker, Sophie P. Chung, Ghadeer K. Dawwas, John R. Horn, Todd A. Miano, Thanh Phuong Pham Nguyen, Charles E. Leonard
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Drug interactions involving benzodiazepines and related drugs (BZDs) are increasingly recognized as a contributor to increased risk of unintentional traumatic injury. Yet, it remains unknown to what extent drug interaction triads (3DIs) may
Externí odkaz:
https://doaj.org/article/863d6552694c41f8a3429b96706fcd46
Autor:
Cheng Chen, Sean Hennessy, Colleen M. Brensinger, Warren B. Bilker, Sascha Dublin, Sophie P. Chung, John R. Horn, Kacie F. Bogar, Charles E. Leonard
Publikováno v:
Clinical and translational scienceREFERENCES.
Antidepressants are associated with traumatic injury and are widely used with other medications. It remains unknown how drug-drug-drug interactions (3DIs) between antidepressants and two other drugs may impact potential injury risks associated with a
Autor:
Cheng Chen, Sean Hennessy, Colleen M. Brensinger, Ghadeer K. Dawwas, Emily K. Acton, Warren B. Bilker, Sophie P. Chung, Sascha Dublin, John R. Horn, Todd A. Miano, Thanh Phuong Pham Nguyen, Samantha E. Soprano, Charles E. Leonard
Publikováno v:
British journal of clinical pharmacology. 88(11)
The aim of this study was to identify skeletal muscle relaxant (SMR) drug-drug-drug interaction (3DI) signals associated with increased rates of unintentional traumatic injury.We conducted automated high-throughput pharmacoepidemiologic screening of
Autor:
Thanh Phuong Pham Nguyen, Samantha E. Soprano, Sean Hennessy, Colleen M. Brensinger, Warren B. Bilker, Todd A. Miano, Emily K. Acton, John R. Horn, Sophie P. Chung, Sascha Dublin, David W. Oslin, Douglas J. Wiebe, Charles E. Leonard
Publikováno v:
J Psychiatr Res
Benzodiazepine receptor agonists and related medications, such as Z-drugs and dual orexin receptor antagonists (BZDs), have been associated with unintentional traumatic injury due to their central nervous system (CNS)-depressant effects. Drug-drug in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d97da58efe630e75336b5d49bf02d04f
https://europepmc.org/articles/PMC9513701/
https://europepmc.org/articles/PMC9513701/
Autor:
Amy L Stark, Ronald J Hause, Lidija K Gorsic, Nirav N Antao, Shan S Wong, Sophie H Chung, Daniel F Gill, Hae K Im, Jamie L Myers, Kevin P White, Richard Baker Jones, M Eileen Dolan
Publikováno v:
PLoS Genetics, Vol 10, Iss 4, p e1004192 (2014)
Annotating and interpreting the results of genome-wide association studies (GWAS) remains challenging. Assigning function to genetic variants as expression quantitative trait loci is an expanding and useful approach, but focuses exclusively on mRNA r
Externí odkaz:
https://doaj.org/article/d70e8f5d77ad47efb599e099fdb8de61
Autor:
Isabelle Ragueneau-Majlessi, René H. Levy, Houda Hachad, Nina Isoherranen, Sophie P Chung, Justin D. Lutz
Publikováno v:
Chemical Research in Toxicology. 25:2285-2300
Drugs that are mainly cleared by a single enzyme are considered more sensitive to drug-drug interactions (DDIs) than drugs cleared by multiple pathways. However, whether this is true when a drug cleared by multiple pathways is co-administered with an
Autor:
Ganesh Rajaraman, Xiaoyan Chu, Ailan Guo, Sibylle Neuhoff, Imad Hanna, Caroline A. Lee, Heleen M. Wortelboer, Guangqing Xiao, Malin Forsgard, Tetsuo Yamagata, Masoud Jamei, Sophie P Chung, Laurent Salphati, Isabelle Ragueneau-Majlessi, Johan E. Palm, Joann Coleman, Michael P. O'Connor, Praveen Balimane, Anne Y. Pak, Libin Li, Kathleen M. Hillgren, Lei Zhang, Krisztina Herédi-Szabó, Jan Shiang Taur, Joe Bentz, Mitchell E. Taub, Shibing Deng, Elke S Perloff, Dietmar Weitz, Harma Ellens, Cindy Q. Xia, Christoph Funk, Dallas Bednarczyk
Publikováno v:
Drug Metabolism and Disposition, 7, 41, 1367-1374
In the 2012 Food and Drug Administration (FDA) draft guidance on drug-drug interactions (DDIs), a new molecular entity that inhibits Pglycoprotein (P-gp) may need a clinical DDI study with a P-gp substrate such as digoxin when themaximumconcentration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba6f60f0f2a333fa7a0b3ee295536585
https://europepmc.org/articles/PMC3684818/
https://europepmc.org/articles/PMC3684818/
Autor:
Eszter Hazai, István Hazai, Isabelle Ragueneau-Majlessi, Zsolt Bikádi, Sophie P Chung, Qingcheng Mao
Publikováno v:
BMC Bioinformatics
Background Human breast cancer resistance protein (BCRP) is an ATP-binding cassette (ABC) efflux transporter that confers multidrug resistance in cancers and also plays an important role in the absorption, distribution and elimination of drugs. Predi