Patients with triple-negative, JAK2V617F- and CALR-mutated essential thrombocythemia share a unique gene expression signature

Autor: Deepti Radia, Anju Kanda, Yvonne Francis, Claire N. Harrison, Shahram Kordasti, Ken I. Mills, Paul Lavender, Richard Dillon, Alexander C. Smith, Sophie Ord, Ghulam J. Mufti, William Villiers, Manohursingh Runglall, James Kaufman-Cook, Donal P. McLornan, Samah Alimam, Michael A. Simpson, Prodromos Chatzikyriakou, Claire Woodley, Beatriz Bellosillo Paricio

Publikováno v: Alimam, S, Villiers, W, Dillon, R, Simpson, M, Runglall, M, Smith, A, Chatzikyriakou, P, Lavender, P, Kanda, A, Mills, K, Bellosillo Paricio, B, Kaufman-Cook, J, Ord, S, Kordasti, S, Radia, D, Woodley, C, Francis, Y, Mufti, G, McLornan, D P & Harrison, C N 2021, ' Patients with triple-negative, JAK2V617F-and CALR-mutated essential thrombocythemia share a unique gene expression signature ', Blood Advances, vol. 5, no. 4, pp. 1059-1068 . https://doi.org/10.1182/bloodadvances.2020003172
Blood Adv

Approximately 10% to 15% of patients with essential thrombocythemia (ET) lack the common driver mutations, so-called “triple-negative” (TN) disease. We undertook a systematic approach to investigate for somatic mutations and delineate gene expres

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https://pure.qub.ac.uk/en/publications/patients-with-triplenegative-jak2v617f-and-calrmutated-essential-thrombocythemia-share-a-unique-gene-expression-signature(92765c90-b4d8-4543-abaf-cf4d2f5fcfeb).html