Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Sophie Nyberg"'
Autor:
Francesca Provenzano, Sophie Nyberg, Debora Giunti, Carola Torazza, Benedetta Parodi, Tiziana Bonifacino, Cesare Usai, Nicole Kerlero de Rosbo, Marco Milanese, Antonio Uccelli, Pamela J. Shaw, Laura Ferraiuolo, Giambattista Bonanno
Publikováno v:
Cells, Vol 11, Iss 23, p 3923 (2022)
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease with no effective cure. Astrocytes display a toxic phenotype in ALS and contribute to motoneuron (MN) degeneration. Modulating astrocytes’ neurotoxicity can reduce MN death. Our pre
Externí odkaz:
https://doaj.org/article/67adbb1742a94f2bae3e34e04e252b01
Autor:
André Varcianna, Monika A. Myszczynska, Lydia M. Castelli, Brendan O'Neill, Yeseul Kim, Jordan Talbot, Sophie Nyberg, Immanuelle Nyamali, Paul R. Heath, Matthew J. Stopford, Guillaume M. Hautbergue, Laura Ferraiuolo
Publikováno v:
EBioMedicine, Vol 40, Iss , Pp 626-635 (2019)
Background: Astrocytes regulate neuronal function, synaptic formation and maintenance partly through secreted extracellular vesicles (EVs). In amyotrophic lateral sclerosis (ALS) astrocytes display a toxic phenotype that contributes to motor neuron (
Externí odkaz:
https://doaj.org/article/05ea110dca0041249eb8a8d9d78a3cba
Autor:
Aroa Duro-Castano, Lena Harker-Kirschneck, Anđela Šarić, Xiaohe Tian, Lei Luo, Joe Forth, Edoardo Scarpa, Pan Xiang, Sophie Nyberg, Zhongping Zhang, Manish R. Vuyyuru, Gavin Fullstone, Yupeng Tian, Azzurra Apriceno, Diana Matias, Loris Rizzello, Diana Moreira Leite, Bin Fang, Alessandro Poma, Giuseppe Battaglia
Publikováno v:
Science Advances
bioRxiv
bioRxiv
Tubule formation acts as cargo transport across the blood-brain barrier.
The blood-brain barrier is made of polarized brain endothelial cells (BECs) phenotypically conditioned by the central nervous system (CNS). Although transport across BECs i
The blood-brain barrier is made of polarized brain endothelial cells (BECs) phenotypically conditioned by the central nervous system (CNS). Although transport across BECs i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb7eedfeace0c4a76f238043ecdc807d
https://doi.org/10.1126/sciadv.abc4397
https://doi.org/10.1126/sciadv.abc4397
Autor:
Eun Sun Kim, Minyeong Kim, Saurabh A. Jain, Young-Jun Shin, Ali Ali, Eun-Hye Kim, Sophie Nyberg, Arshad Majid, Alessandro Poma, Jessica Redgrave, Donghyun Kim, Giuseppe Battaglia, Jin-Ki Kim, Thorsten R. Doeppner, Denis Cecchin, Seung-Hoon Baek, Kyeong-A Kim, Ok-Nam Bae
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
Stroke is one of the commonest causes of death with limited treatment options. L-Carnosine has shown great promise as a neuroprotective agent in experimental stroke, but translation to the clinic is impeded by the large doses needed. We developed and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f31519ed6edead314fc82de571e3493f
https://pubmed.ncbi.nlm.nih.gov/31959846
https://pubmed.ncbi.nlm.nih.gov/31959846
Autor:
André, Varcianna, Monika A, Myszczynska, Lydia M, Castelli, Brendan, O'Neill, Yeseul, Kim, Jordan, Talbot, Sophie, Nyberg, Immanuelle, Nyamali, Paul R, Heath, Matthew J, Stopford, Guillaume M, Hautbergue, Laura, Ferraiuolo
Publikováno v:
EBioMedicine
Background Astrocytes regulate neuronal function, synaptic formation and maintenance partly through secreted extracellular vesicles (EVs). In amyotrophic lateral sclerosis (ALS) astrocytes display a toxic phenotype that contributes to motor neuron (M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f5a07557cd87cabf3cdaaa6297f5f34e
https://pubmed.ncbi.nlm.nih.gov/30711519
https://pubmed.ncbi.nlm.nih.gov/30711519
Publikováno v:
Science translational medicine. 11(482)
Permanent hearing loss affects more than 5% of the world's population, yet there are no nondevice therapies that can protect or restore hearing. Delivery of therapeutics to the cochlea and vestibular system of the inner ear is complicated by their in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04a4d1114de0511f99c930ee3363e9bd
https://pubmed.ncbi.nlm.nih.gov/30842313
https://pubmed.ncbi.nlm.nih.gov/30842313
Autor:
Jens Gaitzsch, Jane E. Preston, Claudia Contini, Juzaili Azizi, Giorgio Volpe, Sophie Nyberg, Lorena Ruiz-Pérez, Giuseppe Battaglia, Gavin Fullstone, Xiaohe Tian, Adrian Joseph, Denis Cecchin
In recent years, scientists have created artificial microscopic and nanoscopic self-propelling particles, often referred to as nano- or micro-swimmers, capable of mimicking biological locomotion and taxis. This active diffusion enables the engineerin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eeb4816cd472f272dc258996052623e3
Designing nanoparticles that effectively enter the central nervous system (CNS) rapidly and without alteration is one of the major challenges in the use of nanotechnology for the brain. In this chapter, we explore the process of transcytosis, a recep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c78ac3396bf217816cece25bb6abd3b6
https://doi.org/10.1016/bs.irn.2016.06.001
https://doi.org/10.1016/bs.irn.2016.06.001
Autor:
Sean M. Davidson, Alessandro Poma, Beppe Battaglia, Sapna Arjun, Dina Radenkovic, Derek M. Yellon, Sophie Nyberg
Publikováno v:
Heart. 102:A115.2-A115
Background Exosomes -– nano-sized, lipidvesicles released by cells into the blood – can protect the myocardium against ischaemia/reperfusion (IR) injury. 1 This cardioprotection is mediated by heat shock protein 70 (HSP70) on the exosome surface
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9974330d6c55b9c59b3fa7edd1642690
https://doi.org/10.1136/heartjnl-2016-309890.162
https://doi.org/10.1136/heartjnl-2016-309890.162