CSF-contacting neurons regulate locomotion by relaying mechanical stimuli to spinal circuits

Autor: Urs Lucas Böhm, Andrew Prendergast, Lydia Djenoune, Sophie Nunes Figueiredo, Johanna Gomez, Caleb Stokes, Sonya Kaiser, Maximilliano Suster, Koichi Kawakami, Marine Charpentier, Jean-Paul Concordet, Jean-Paul Rio, Filippo Del Bene, Claire Wyart

Publikováno v: Nature Communications, Vol 7, Iss 1, Pp 1-8 (2016)

CSF-contacting neurons are known to project to locomotor CPGs although their relevance to active locomotion is unclear. Here, the authors show that these cells constitute a mechanosensory organ relying on PKD2L1 channels to detect spinal cord curvatu

Externí odkaz: https://doaj.org/article/25791dd165b94a4e9900651c693643a8

CSF-contacting neurons regulate locomotion by relaying mechanical stimuli to spinal circuits

Autor: Johanna Gomez, Caleb Stokes, Andrew Prendergast, J.P. Rio, Maximilliano L. Suster, Jean-Paul Concordet, Sonya Kaiser, Filippo Del Bene, Claire Wyart, Marine Charpentier, Urs Lucas Böhm, Sophie Nunes Figueiredo, Koichi Kawakami, Lydia Djenoune

Publikováno v: Nature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
Nature Communications
Nature Communications, 2016, 7, pp.10866 ⟨10.1038/ncomms10866⟩
Nature Communications, Nature Publishing Group, 2016, 7, pp.10866 ⟨10.1038/ncomms10866⟩

Throughout vertebrates, cerebrospinal fluid-contacting neurons (CSF-cNs) are ciliated cells surrounding the central canal in the ventral spinal cord. Their contribution to modulate locomotion remains undetermined. Recently, we have shown CSF-cNs modu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c51c3ab998e7323b7351e81d3cd91cf
https://doaj.org/article/25791dd165b94a4e9900651c693643a8

Mechanosensory neurons control the timing of spinal microcircuit selection during locomotion

Autor: Olivier Thouvenin, Claire Wyart, Andrew Prendergast, Hugues Pascal-Moussellard, Steven Knafo, Sophie Nunes Figueiredo, Charles William Dickey, Alexandre Parrin, Kevin Fidelin, Po-En Brian Tseng, Urs Lucas Böhm

Publikováno v: eLife, Vol 6 (2017)
eLife
eLife, eLife Sciences Publication, 2017, 2017 (6), pp.e25260. ⟨10.7554/eLife.25260⟩

Despite numerous physiological studies about reflexes in the spinal cord, the contribution of mechanosensory feedback to active locomotion and the nature of underlying spinal circuits remains elusive. Here we investigate how mechanosensory feedback s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2810cab61d17eba37408edad499864b1
https://elifesciences.org/articles/25260