Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Sophie North"'
Publikováno v:
Refuge, Vol 37, Iss 1 (2021)
Research demonstrates the complex nature of supporting forced migrant populations; however, there is almost no research on volunteer experience of supporting forced migrants. This study explored the experiences of volunteer mentors in the United King
Externí odkaz:
https://doaj.org/article/92461b79c1f5479192eb3de34e00ce35
Publikováno v:
Refuge, Vol 36, Iss 1 (2020)
Many forced migrants experience trauma in pre-migration, journeying, and post-migration phases of flight. Therefore appropriate mental health provision is required. Whilst previous reviews have explored the experiences of health-care staff in support
Externí odkaz:
https://doaj.org/article/75c0342bc2ac4e6bb278810925116edd
Autor:
Emily Player, Heidi Gure-Klinke, Sophie North, Donald Lane, Sarah Hanson, Veena Rodrigues, Graham Culyer
Publikováno v:
Education for Primary Care. 30:368-374
Expert patients have recognised benefits for both students and patients in medical education. However, marginalised patients such as homeless patients are less likely to participate. Learning from such individuals is crucial for future doctors, who c
Autor:
Olivia Lanvin, Stephanie Bianco, Jean-Marc M. Vanacker, Claire Macari, Violaine Tribollet, Sophie North
Publikováno v:
Journal of Biological Chemistry. 284:23286-23292
High expression of the estrogen receptor-related receptor (ERR)-α in human tumors is correlated to a poor prognosis, suggesting an involvement of the receptor in cell proliferation. In this study, we show that a synthetic compound (XCT790) that modu
Autor:
Frédéric Mazurier, Francis Belloc, Hubert de Verneuil, Alain Taieb, Hamid Reza Rezvani, Sophie North, Thierry Letellier, Rodrigue Rossignol, Sophie Dedieu
Publikováno v:
Journal of Biological Chemistry. 282:16413-16422
Hypoxia-inducible factor-1 (HIF-1) is a major transcription factor sensitive to oxygen levels, which responds to stress factors under both hypoxic and nonhypoxic conditions. UV irradiation being a common stressor of skin, we looked at the effect of U
Autor:
Gérard Déléris, Marion Bouchecareilh, Sophie North, Benjamin Drogat, Cyril Petibois, Michel Moenner, Eric Chevet, Andreas Bikfalvi
Publikováno v:
Journal of Cellular Physiology. 212:463-472
Tumor ischemia participates in angiogenesis and cancer progression through cellular responses to hypoxia and nutrient deprivation. However, the contribution of amino acids limitation to this process remains poorly understood. Using serum-free cell cu
Publikováno v:
Cancer Letters. 218:1-14
Angiogenesis in tumors is controlled by the so-called 'angiogenic switch' which allows the passage from low invasive and poorly vascularized tumors to highly invasive and angiogenic tumors. A number of cellular stress factors such as hypoxia, nutrien
Publikováno v:
Biochemical Pharmacology. 65:1129-1137
WR1065 is an aminothiol with selective cytoprotective effects in normal compared to cancer cells, which is used to protect tissues against the damaging effect of radiation and chemotherapeutic drugs. WR1065 has been shown to induce wild-type p53 accu
Autor:
Pierre Hainaut, Patrice Lassus, Gerald Verhaegh, Maria-Gloria Luciani, Sophie North, Stéphanie Courtois, Ula Hibner, Moshe Oren
Publikováno v:
Oncogene
Oncogene, Nature Publishing Group, 2002, 21 (44), pp.6722--6728. ⟨10.1038/sj.onc.1205874⟩
Oncogene, Nature Publishing Group, 2002, 21 (44), pp.6722--6728. ⟨10.1038/sj.onc.1205874⟩
The tumor suppressor protein p53 is ubiquitously expressed as a major isoform of 53 kD, but several forms of lower molecular weight have been observed. Here, we describe a new isoform, DeltaN-p53, produced by internal initiation of translation at cod
Publikováno v:
Molecular Carcinogenesis. 33:181-188
The aminothiol WR1065, the active metabolite of the cytoprotector amifostine, exerts its antimutagenic effects through free-radical scavenging and other unknown mechanisms. In an earlier report, we showed that WR1065 activates wild-type p53 in MCF-7