Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Sophie Neugebauer"'
Autor:
Julia Leonhardt, Mirrin J. Dorresteijn, Sophie Neugebauer, Diana Mihaylov, Julia Kunze, Ignacio Rubio, Frank-Stephan Hohberger, Silke Leonhardt, Michael Kiehntopf, Klaus Stahl, Christian Bode, Sascha David, Frank A. D. T. G. Wagener, Peter Pickkers, Michael Bauer
Publikováno v:
Critical Care, Vol 27, Iss 1, Pp 1-14 (2023)
Abstract Background Sepsis-induced immunosuppression is a frequent cause of opportunistic infections and death in critically ill patients. A better understanding of the underlying mechanisms is needed to develop targeted therapies. Circulating bile a
Externí odkaz:
https://doaj.org/article/529c4647bde24d439a342d5da2e8642e
Autor:
Friederike Dellbrügge, Lena D. Jesse, Anna Medyukhina, Na Liu, Sophie Neugebauer, Markus Freißmuth, Stephanie Höppener, Marc T. Figge, Helen Morrison, Lars B. Riecken, Adrian T. Press
Publikováno v:
Heliyon, Vol 9, Iss 11, Pp e21009- (2023)
Background & aims: Excretory liver failure is frequently associated with poor prognosis in critically ill patients. It is characterized by the loss of canalicular membrane export pumps at the hepatocyte membrane. The membrane export pump Multidrug re
Externí odkaz:
https://doaj.org/article/8f74b97aadd547da842b249f337999b4
Autor:
Jessica Hoff, Ling Xiong, Tobias Kammann, Sophie Neugebauer, Julia M. Micheel, Nikolaus Gaßler, Michael Bauer, Adrian T. Press
Publikováno v:
Cell Death and Disease, Vol 14, Iss 4, Pp 1-16 (2023)
Abstract Necroptosis facilitates cell death in a controlled manner and is employed by many cell types following injury. It plays a significant role in various liver diseases, albeit the cell-type-specific regulation of necroptosis in the liver and es
Externí odkaz:
https://doaj.org/article/fafdec10994e41eb93f99e613ef4c196
Autor:
Lars-Olav Harnisch, Sophie Neugebauer, Diana Mihaylov, Abass Eidizadeh, Bozena Zechmeister, Ilko Maier, Onnen Moerer
Publikováno v:
Biomedicines, Vol 11, Iss 11, p 2947 (2023)
(1) Background: Bile acids, known as aids in intestinal fat digestion and as messenger molecules in serum, can be detected in cerebrospinal fluid (CSF), although the blood–brain barrier is generally an insurmountable obstacle for bile acids. The ex
Externí odkaz:
https://doaj.org/article/8d37d2bfd00e4cf09b48ed6b95a1ecbb
Autor:
Andreas Stallmach, Philip Grunert, Johannes Stallhofer, Bettina Löffler, Michael Baier, Jürgen Rödel, Michael Kiehntopf, Sophie Neugebauer, Dietmar H. Pieper, Howard Junca, Andrea Tannapfel, Ute Merkel, Ulrike Schumacher, Maria Breternitz-Gruhne, Tabitha Heller, Anja Schauer, Michael Hartmann, Arndt Steube
Publikováno v:
Trials, Vol 23, Iss 1, Pp 1-10 (2022)
Abstract Background Ulcerative colitis (UC) is a chronic inflammatory bowel disease with significant morbidity and mortality. Although the precise cause remains unknown, disturbances in the intestinal microbial community have been linked to its patho
Externí odkaz:
https://doaj.org/article/22c8ea2e5f464d9f8887a45b7cb15fb4
Autor:
Gloria Asantewaa, Nsoh Godwin Anabire, Michael Bauer, Sebastian Weis, Sophie Neugebauer, Osbourne Quaye, Gideon Kofi Helegbe
Publikováno v:
Diseases, Vol 11, Iss 3, p 94 (2023)
Plasmodium falciparum (P. falciparum) and hepatitis B virus (HBV) co-infection is on the rise among pregnant women in northern Ghana. Mono-infection with either of these two pathogens results in unique metabolic alterations. Thus, we aimed to explica
Externí odkaz:
https://doaj.org/article/07e4c9290f0d40efbdc11f48e1c6046f
Autor:
Julia Leonhardt, Raphael S. Haider, Christoph Sponholz, Silke Leonhardt, Julia Drube, Katrin Spengler, Diana Mihaylov, Sophie Neugebauer, Michael Kiehntopf, Nevin A. Lambert, Andreas Kortgen, Tony Bruns, Frank Tacke, Carsten Hoffmann, Michael Bauer, Regine Heller
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 1, Pp 25-40 (2021)
Background & Aims: Retention of bile acids in the blood is a hallmark of liver failure. Recent studies have shown that increased serum bile acid levels correlate with bacterial infection and increased mortality. However, the mechanisms by which circu
Externí odkaz:
https://doaj.org/article/f2898bb220504471a55ccd6030fbf158
Autor:
Waqas Khaliq, Peter Großmann, Sophie Neugebauer, Anna Kleyman, Roberta Domizi, Sara Calcinaro, David Brealey, Markus Gräler, Michael Kiehntopf, Sascha Schäuble, Mervyn Singer, Gianni Panagiotou, Michael Bauer
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 18, Iss , Pp 3678-3691 (2020)
Sepsis remains a major cause of death despite advances in medical care. Metabolic deregulation is an important component of the survival process. Metabolomic analysis allows profiling of critical metabolic functions with the potential to classify pat
Externí odkaz:
https://doaj.org/article/e0cee85bf8e2496b87bbfc47b06ef861
Autor:
Tarek Bekfani, Mohamed Bekhite, Sophie Neugebauer, Steffen Derlien, Ali Hamadanchi, Jenny Nisser, Marion S. Hilse, Daniela Haase, Tom Kretzschmar, Mei-Fang Wu, Michael Lichtenauer, Michael Kiehntopf, Stephan von Haehling, Peter Schlattmann, Gabriele Lehmann, Marcus Franz, Sven Möbius-Winkler, Christian Schulze
Publikováno v:
Cells, Vol 11, Iss 10, p 1674 (2022)
Aims: Metabolic and structural perturbations in skeletal muscle have been found in patients with heart failure (HF) both with preserved (HFpEF) and reduced (HFrEF) ejection fraction in association with reduced muscle endurance (RME). We aimed in the
Externí odkaz:
https://doaj.org/article/2af77d2db5fa47db87adebdf9a997da9
Autor:
Marion S. Hilse, Tom Kretzschmar, Rudin Pistulli, Marcus Franz, Tarek Bekfani, Daniela Haase, Sophie Neugebauer, Michael Kiehntopf, Jan F. Gummert, Hendrik Milting, P. Christian Schulze
Publikováno v:
Metabolites, Vol 11, Iss 9, p 615 (2021)
Chronic heart failure (HF) is a clinical syndrome characterized by functional impairments of the myocardium. Metabolic and clinical changes develop with disease progression. In an advanced state, left ventricular assist devices (LVADs) are implanted
Externí odkaz:
https://doaj.org/article/8f152033f49e45c9aed6d1b1602ee657