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pro vyhledávání: '"Sophie Moullec"'
Long-term microdystrophin gene therapy is effective in a canine model of Duchenne muscular dystrophy
Autor:
Caroline Le Guiner, Laurent Servais, Marie Montus, Thibaut Larcher, Bodvaël Fraysse, Sophie Moullec, Marine Allais, Virginie François, Maeva Dutilleul, Alberto Malerba, Taeyoung Koo, Jean-Laurent Thibaut, Béatrice Matot, Marie Devaux, Johanne Le Duff, Jack-Yves Deschamps, Inès Barthelemy, Stéphane Blot, Isabelle Testault, Karim Wahbi, Stéphane Ederhy, Samia Martin, Philippe Veron, Christophe Georger, Takis Athanasopoulos, Carole Masurier, Federico Mingozzi, Pierre Carlier, Bernard Gjata, Jean-Yves Hogrel, Oumeya Adjali, Fulvio Mavilio, Thomas Voit, Philippe Moullier, George Dickson
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Duchenne muscular dystrophy is a progressive degenerative disease of muscles caused by mutations in the dystrophin gene. Here the authors use AAV vectors to deliver microdystrophin to dogs with muscular dystrophy, and show restoration of dystrophin e
Externí odkaz:
https://doaj.org/article/d425f7f6bf364aa99c6850ae61ecdd6b
Autor:
Judith Lorant, Thibaut Larcher, Nicolas Jaulin, Benoît Hedan, Aurélie Lardenois, Isabelle Leroux, Laurence Dubreil, Mireille Ledevin, Hélicia Goubin, Sophie Moullec, Jack-Yves Deschamps, Chantal Thorin, Catherine André, Oumeya Adjali, Karl Rouger
Publikováno v:
Cell Transplantation, Vol 27 (2018)
Growing demonstrations of regenerative potential for some stem cells led recently to promising therapeutic proposals for neuromuscular diseases. We have shown that allogeneic MuStem cell transplantation into Golden Retriever muscular dystrophy (GRMD)
Externí odkaz:
https://doaj.org/article/94c2e7d00d8d4b60b00dad13e3e6a9ea
Autor:
Benoit Delache, Bérangère Bertin, Jack-Yves Deschamps, Virginie Latournerie, Carole Masurier, Christian Leborgne, Sophie Moullec, Olivier Benveniste, Roger Le Grand, Philippe Moullier, Fanny Collaud, Sylvie Boutin, Otto Wilhelm Merten, Philippe Veron, Laetitia van Wittenberghe, Yves Fromes, Nathalie Dereuddre-Bosquet, Federico Mingozzi
Publikováno v:
Scientific Reports
Scientific Reports, Nature Publishing Group, 2020, 10 (1), pp.864. ⟨10.1038/s41598-020-57893-z⟩
Scientific Reports, 2020, 10 (1), pp.864. ⟨10.1038/s41598-020-57893-z⟩
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports, Nature Publishing Group, 2020, 10 (1), pp.864. ⟨10.1038/s41598-020-57893-z⟩
Scientific Reports, 2020, 10 (1), pp.864. ⟨10.1038/s41598-020-57893-z⟩
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Neutralizing antibodies directed against adeno-associated virus (AAV) are commonly found in humans. In seropositive subjects, vector administration is not feasible as antibodies neutralize AAV vectors even at low titers. Consequently, a relatively la
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::546fe2adb17ce6e26f7d3cb1efb28b38
https://www.hal.inserm.fr/inserm-02489693/file/s41598-020-57893-z.pdf
https://www.hal.inserm.fr/inserm-02489693/file/s41598-020-57893-z.pdf
Autor:
Laurence Dubreil, Hélicia Goubin, Isabelle Leroux, Judith Lorant, Aurélie Lardenois, Karl Rouger, Sophie Moullec, Catherine André, Oumeya Adjali, Nicolas Jaulin, Jack-Yves Deschamps, Benoit Hedan, Thibaut Larcher, Chantal Thorin, Mireille Ledevin
Publikováno v:
Cell Transplantation
Cell Transplantation, Cognizant Communication Corporation, 2018, 27 (7), pp.1096-1110. ⟨10.1177/0963689718776306⟩
Cell Transplantation, 096368971877630. (2018)
Cell Transplantation, 2018, pp.963689718776306. 〈10.1177/0963689718776306〉
Cell Transplantation, 2018, 27 (7), pp.1096-1110. ⟨10.1177/0963689718776306⟩
Cell Transplantation, Vol 27 (2018)
Cell Transplantation, Cognizant Communication Corporation, 2018, 27 (7), pp.1096-1110. ⟨10.1177/0963689718776306⟩
Cell Transplantation, 096368971877630. (2018)
Cell Transplantation, 2018, pp.963689718776306. 〈10.1177/0963689718776306〉
Cell Transplantation, 2018, 27 (7), pp.1096-1110. ⟨10.1177/0963689718776306⟩
Cell Transplantation, Vol 27 (2018)
Growing demonstrations of regenerative potential for some stem cells led recently to promising therapeutic proposals for neuromuscular diseases. We have shown that allogeneic MuStem cell transplantation into Golden Retriever muscular dystrophy (GRMD)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::940e7290bdcbdea6b4ac9a8a803cae0b
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01812518
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01812518
Long-term microdystrophin gene therapy is effective in a canine model of Duchenne muscular dystrophy
Autor:
Virginie François, Oumeya Adjali, Jean-Yves Hogrel, George Dickson, Thibaut Larcher, Maeva Dutilleul, Taeyoung Koo, Marie Montus, Stéphane Ederhy, Stéphane Blot, M. Allais, Carole Masurier, Alberto Malerba, Marie Devaux, B. Matot, Karim Wahbi, Sophie Moullec, Bernard Gjata, Bodvael Fraysse, Laurent Servais, Fulvio Mavilio, Inès Barthélémy, Pierre G. Carlier, Takis Athanasopoulos, Isabelle Testault, Samia Martin, Jack-Yves Deschamps, Philippe Moullier, Federico Mingozzi, Philippe Veron, Christophe Georger, Johanne Le Duff, Caroline Le Guiner, Thomas Voit, Jean-Laurent Thibaut
Publikováno v:
Nature Communications
Nature Communications, 2017, 8 (1), pp.16105. ⟨10.1038/ncomms16105⟩
Nature communications (8), 16105. (2017)
Nature Communications, Nature Publishing Group, 2017, 8 (1), pp.16105. ⟨10.1038/ncomms16105⟩
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Nature Communications, 2017, 8 (1), pp.16105. ⟨10.1038/ncomms16105⟩
Nature communications (8), 16105. (2017)
Nature Communications, Nature Publishing Group, 2017, 8 (1), pp.16105. ⟨10.1038/ncomms16105⟩
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Duchenne muscular dystrophy (DMD) is an incurable X-linked muscle-wasting disease caused by mutations in the dystrophin gene. Gene therapy using highly functional microdystrophin genes and recombinant adeno-associated virus (rAAV) vectors is an attra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c348d77df95e4b68a2b7f4ada280b2b
https://univ-evry.hal.science/hal-02179396
https://univ-evry.hal.science/hal-02179396
Autor:
Thibaut Larcher, V. Guilloux, Carinne Roudaut, Isabelle Richard, Jack-Yves Deschamps, Sophie Moullec, William Lostal
Publikováno v:
Neuromuscular Disorders
22nd International Annual Congress of the World-Muscle-Society (WMS)
22nd International Annual Congress of the World-Muscle-Society (WMS), Oct 2017, Saint Malo, France. pp.1, ⟨10.1016/j.nmd.2017.06.186⟩
22nd International Annual Congress of the World-Muscle-Society (WMS)
22nd International Annual Congress of the World-Muscle-Society (WMS), Oct 2017, Saint Malo, France. pp.1, ⟨10.1016/j.nmd.2017.06.186⟩
National audience
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5ab6473711ee28cb8e8d1006924d9f4
https://hal.inrae.fr/hal-02735155
https://hal.inrae.fr/hal-02735155
Autor:
L. Servais, Takis Athanasopoulos, Oumeya Adjali, F Mingozzi, George Dickson, J.Y. Hogrel, Yan Cherel, Pierre G. Carlier, Marie Montus, Taeyoung Koo, T. Voit, Sophie Moullec, Fulvio Mavilio, Philippe Moullier, Bernard Gjata, F. Bodvael, C. Le Guiner, Carole Masurier
Publikováno v:
20. International Congress of the World-Muscle-Society
20. International Congress of the World-Muscle-Society, Sep 2015, Brighton, United Kingdom. Elsevier Ltd, Neuromuscular Disorders, 25, pp.1, 2015, ⟨10.1016/j.nmd.2015.06.458⟩
20. International Congress of the World-Muscle-Society, Sep 2015, Brighton, United Kingdom. Elsevier Ltd, Neuromuscular Disorders, 25, pp.1, 2015, ⟨10.1016/j.nmd.2015.06.458⟩
International audience; Duchenne muscular dystrophy (DMD) is an X-linked inherited muscle-wasting disease primarily affecting young boys with a prevalence of 1:5000. The disease is caused by loss-of-function mutations in the gene encoding for the Dys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73254e184ed560bf9fe76df200a1fb3a
https://hal.inrae.fr/hal-02744289
https://hal.inrae.fr/hal-02744289
Autor:
Sophie Moullec, Taeyoung Koo, Fulvio Mavilio, Bernard Gjata, Takis Athanasopoulos, Thomas Voit, Marie Montus, Philippe Moullier, Matthias Hebben, Oumeya Adjali, Bodvael Fraysse, Federico Mingozzi, George Dickson, Thibaut Larcher, Alberto Malerba, Yan Cherel, Carole Masurier, Jean-Yves Hogrel, Pierre G. Carlier, Christine Le Bec, Caroline Le Guiner, Laurent Servais
Publikováno v:
Molecular Therapy. 24:S200
Duchenne Muscular Dystrophy (DMD) is a X-linked inherited muscle-wasting disease primarily affecting young boys with a prevalence of 1:5,000. The disease is caused by loss-of-function mutations in the gene encoding for the Dystrophin protein and is c
Autor:
Yan Cherel, Philippe Veron, F. Barnay-Toutain, Virginie Latournerie, Christian Leborgne, Jean-Laurent Thibaud, Marie Montus, Claire Wary, Nicolas Jaulin, C. Le Guiner, Claire Domenger, Christel Rivière, Oumeya Adjali, H. Goubin, T. Voit, Carole Masurier, Lydie Guigand, N. Delaunay, Philippe Moullier, Sylvie Boutin, Diana Desgue, B. Matot, Gisèle Bonne, Virginie François, J.Y. Hogrel, Maeva Dutilleul, L. Servais, Pierre G. Carlier, Marie Devaux, M. Allais, Sophie Moullec, J. Le Duff, Mickaël Guilbaud, Jack-Yves Deschamps, T. Larche
Publikováno v:
Neuromuscular Disorders. 24:822
We have previously demonstrated that a recombinant adeno-associated virus vector, serotype 8 (rAAV8) carrying a modified U7snRNA sequence promoting exon skipping injected in GRMD by locoregional transvenous perfusion of the forelimb, restores up to 8
Autor:
Jean-Laurent Thibaud, Yan Cherel, Claire Wary, Sophie Moullec, T. Voit, S. Roques, C. Le Guiner, Pierre G. Carlier, L. Servais, Luis Garcia, Noura Azzabou, Philippe Moullier, Yves Fromes, Marie Montus
Publikováno v:
Neuromuscular Disorders. 22:859
Replacement therapy of dystrophinopathies has begun with promising results both in animals and in patients. Non-invasive quantitative tools are needed to evaluate its potential benefits or side effects but also to determine the optimal protocol. Fift