Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Sophie Minaee"'
Autor:
Graham Anderson, Arlene H. Sharpe, Johan Verhagen, Catherine A. Sabatos, David C. Wraith, Leona Gabryšová, Sophie Minaee
Publikováno v:
Proceedings of the National Academy of Sciences. 106:3306-3311
It is generally acknowledged that cytotoxic T-lymphocyte–associated antigen-4 (CTLA-4/CD152) plays a pivotal role in the regulation of T-cell activation and the establishment of self-tolerance in the periphery. CTLA-4–deficient (CTLA-4KO) mice de
Autor:
David C. Wraith, Anette Sundstedt, Sophie Minaee, Kirsty S. Nicolson, Emma J. O’Neill, Streeter Heather Barbara
Publikováno v:
The Journal of Immunology. 176:5329-5337
Recent studies have emphasized the importance of T cells with regulatory/suppressor properties in controlling autoimmune diseases. A number of different types of regulatory T cells have been described with the best characterized being the CD25+ popul
Autor:
Per Anderson, Sophie Minaee, David C. Wraith, Li Li, Anette Sundstedt, Zihni Acar Yazici, Kirsty S. Nicolson, Ping Wang, R T Woolf, Suling Li, Nathaniel T Whitley
Publikováno v:
The Journal of Immunology. 174:310-319
Intranasal administration of peptide Ac1–9[4Y], based on the N-terminal epitope of myelin basic protein, can induce CD4+ T cell tolerance, and suppress experimental autoimmune encephalomyelitis induction. The peptide-induced regulatory T (PI-TReg)
Autor:
Kathryn P. Burdon, Sophie Minaee, Gregory A. Hawkins, Sarah L. Allford, Donald W. Bowden, Geoffrey Russell, Andrew D Mumford, D. Wynne Jones
Publikováno v:
British Journal of Haematology. 127:220-223
An elderly patient with no abnormal bleeding presented with prolongation of the activated partial thromboplastin time (aPTT). Preincubation of plasma with aPTT reagent caused shortening of the abnormal clotting time. Plasma prekallikrein (PK) activit
Autor:
Pierangela Sabbattini, Niall Dillon, Sophie Minaee, Andrew Georgiou, Mats Lundgren, Cheok-man Chow
Publikováno v:
Cell. 103(5):733-743
The mechanisms of transcriptional activation in heterochromatin were investigated by using FISH to directly visualize changes in chromatin organization during activation of a heterochromatic λ5 transgene. A DNase I hypersensitive site was shown to r
Autor:
Per Anderson, David C. Wraith, Kirsty S. Nicolson, María Elena Rodríguez-Cabezas, Alistair L. J. Symonds, Anette Sundstedt, Suling Li, Ping Wang, Sabah Khalid, Barbara Ada Manzo, Sophie Minaee
Repetitive antigen stimulation induces peripheral T cell tolerance in vivo. It is not known, however, whether multiple stimulations merely suppress T cell activation or, alternatively, change the transcriptional program to a distinct, tolerant state.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1b0876cd91cd1fccb1be3ee0ee82af9
https://europepmc.org/articles/PMC2652694/
https://europepmc.org/articles/PMC2652694/
Autor:
Sophie Minaee, Thomas Barthlott, Franck J. Barrat, David C. Wraith, Anne O'Garra, Jillian R. Christensen, Andre Boonstra, Emma J. O’Neill, Brigitta Stockinger, Pedro L. Vieira
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 172(10)
Regulatory T cells (TReg) control immune responses to self and nonself Ags. The relationship between Ag-driven IL-10-secreting TReg (IL-10-TReg) and naturally occurring CD4+CD25+ TReg is as yet unclear. We show that mouse IL-10-TReg obtained using ei