Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Sophie Mainguy‐Seers"'
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 38, Iss 3, Pp 1835-1841 (2024)
Abstract Background Salbutamol and hyoscine butylbromide (HBB) are commonly used bronchodilators in horses with severe asthma (SA). Objective To compare the bronchodilation potency, duration, and adverse effects of salbutamol and HBB in SA. Animals S
Externí odkaz:
https://doaj.org/article/9fa12a38759e4b548b5e667528245cb6
Autor:
Eloïse Greim, Jan Naef, Sophie Mainguy‐Seers, Jean‐Pierre Lavoie, Sophie Sage, Gaudenz Dolf, Vinzenz Gerber
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 38, Iss 1, Pp 495-504 (2024)
Abstract Background Standard thoracic auscultation suffers from limitations, and no systematic analysis of breath sounds in asthmatic horses exists. Objectives First, characterize breath sounds in horses recorded using a novel digital auscultation de
Externí odkaz:
https://doaj.org/article/20084f0609ca442183c214e9094bf65c
Publikováno v:
Animals, Vol 14, Iss 22, p 3310 (2024)
Vitamin D deficiency is associated with asthma development and severity of symptoms in humans, but whether the same occurs in horses is unknown. We aimed to determine whether the serum vitamin D levels differ in horses with asthma compared to control
Externí odkaz:
https://doaj.org/article/2f563385aa854226a2097657ba1fbad5
Autor:
Sophie Mainguy-Seers, Roxane Boivin, Sheila Pourali Dogaheh, Francis Beaudry, Pierre Hélie, Alvaro G. Bonilla, James G. Martin, Jean-Pierre Lavoie
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Steroid resistance in asthma has been associated with neutrophilic inflammation and severe manifestations of the disease. Macrolide add-on therapy can improve the quality of life and the exacerbation rate in refractory cases, possibly with g
Externí odkaz:
https://doaj.org/article/4e29fcaedb0b413c9473aede0318ae78
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 35, Iss 4, Pp 2045-2057 (2021)
Abstract Despite substantial research efforts to improve the treatment and outcome of horses with asthma, glucocorticoids (GC) remain the cornerstone of drug treatment of this prevalent disease. The high efficacy of GC to relieve airway obstruction e
Externí odkaz:
https://doaj.org/article/7b47a573803e42aebb2e8ca8a2585a00
Autor:
Sophie Mainguy-Seers, Francis Beaudry, Christopher Fernandez-Prada, James G. Martin, Jean-Pierre Lavoie
Publikováno v:
Cells, Vol 11, Iss 21, p 3347 (2022)
Extracellular vesicles (EVs) contribute to intercellular communication through the transfer of their rich cargo to recipient cells. The EVs produced by LPS-stimulated neutrophils from healthy humans and horses increase airway smooth muscle (ASM) prol
Externí odkaz:
https://doaj.org/article/9da7a9cea25d4bc696ec5b16e77afc91
Publikováno v:
Animals, Vol 12, Iss 4, p 494 (2022)
While the prevalence of asthma is higher in boys than in girls during childhood, this tendency reverses at puberty, suggesting an effect of sex hormones on the disease pathophysiology. Fluctuations of asthma severity concurring with the estrus cycle
Externí odkaz:
https://doaj.org/article/7743d994e4494f8480e658ec4c1b8932
Publikováno v:
Equine Veterinary Journal. 51:641-645
Background Inhaled corticosteroids are effective in the treatment of equine asthma. A recent study reported that nebulisation of injectable dexamethasone had low systemic bioavailability in healthy horses and could represent a cost-effective therapy
Publikováno v:
A63. PATHOPHYSIOLOGY OF ASTHMA IN CELLS, TISSUES, AND ANIMAL MODELS.
Autor:
Jean-Pierre Lavoie, Sophie Mainguy-Seers, Amandine Vargas, Christian Bédard, Pierre Hélie, Olivia Labrecque
Publikováno v:
The Veterinary record. 185(5)
Neutrophilic inflammation is believed to contribute to the airway obstruction and remodelling in equine asthma. Azithromycin, an antibiotic with immunomodulatory properties, reduces pulmonary neutrophilia and hyper-responsiveness in human asthmatics