Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Sophie M. Poznanski"'
Autor:
Ana L. Portillo, Richard Hogg, Sophie M. Poznanski, Eduardo A. Rojas, Niamh J. Cashell, Joanne A. Hammill, Marianne V. Chew, Mira M. Shenouda, Tyrah M. Ritchie, Quynh T. Cao, Jeremy A. Hirota, Sukhbinder Dhesy-Thind, Jonathan L. Bramson, Ali A. Ashkar
Publikováno v:
iScience, Vol 24, Iss 6, Pp 102619- (2021)
Summary: Despite the remarkable success of chimeric antigen receptor (CAR)-T cells against hematologic malignancies, severe off-tumor effects have constrained their use against solid tumors. Recently, CAR-engineered natural killer (NK) cells have eme
Externí odkaz:
https://doaj.org/article/be2ea8985203437bad60b92b16b38d23
Autor:
Amanda J. Lee, Firoz Mian, Sophie M. Poznanski, Michele Stackaruk, Tiffany Chan, Marianne V. Chew, Ali A. Ashkar
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
NK cells are a key antiviral component of the innate immune response to HSV-2, particularly through their production of IFN-γ. It is still commonly thought that type I IFN activates NK cell function; however, rather than requiring the type I IFN rec
Externí odkaz:
https://doaj.org/article/afa462e16097466aaae09852f512e2ee
Autor:
Sophie M. Poznanski, Ali A. Ashkar
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
NK cells are capable of an array of functions that range widely from their classic anti-tumor and anti-viral cytotoxic effector functions, to their critical regulatory roles in controlling inflammatory immune responses and promoting tissue growth. Ho
Externí odkaz:
https://doaj.org/article/ba470d7ef1424d22aedb937205e9e4cd
Publikováno v:
Cells, Vol 10, Iss 3, p 708 (2021)
As highlighted by the COVID-19 global pandemic, elderly individuals comprise the majority of cases of severe viral infection outcomes and death. A combined inability to control viral replication and exacerbated inflammatory immune activation in elder
Externí odkaz:
https://doaj.org/article/c4ad4557cb8d47fa8cae2850865f7164
Autor:
Ali A. Ashkar, Hal W. Hirte, Dean A. Lee, Jonathan L. Bramson, Martin Butcher, Isabella Y. Fan, Joanne A. Hammill, Amanda J. Lee, Marianne V. Chew, Tina Nham, Sophie M. Poznanski
Natural killer (NK) cells are useful for cancer immunotherapy and have proven clinically effective against hematologic malignancies. However, immunotherapies for poor prognosis solid malignancies, including ovarian cancer, have not been as successful
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28fde7221724f3dcb346f3da713a0077
https://doi.org/10.1158/2326-6066.c.6548206.v1
https://doi.org/10.1158/2326-6066.c.6548206.v1
Autor:
Ali A. Ashkar, Hal W. Hirte, Dean A. Lee, Jonathan L. Bramson, Martin Butcher, Isabella Y. Fan, Joanne A. Hammill, Amanda J. Lee, Marianne V. Chew, Tina Nham, Sophie M. Poznanski
Expression of NK cell activation and inhibitory ligands on resistant primary ovarian cancer cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5246be899e0432b7c626a781070dc853
https://doi.org/10.1158/2326-6066.22536676.v1
https://doi.org/10.1158/2326-6066.22536676.v1
Autor:
Ali A. Ashkar, Katherine Radford, Sophie M. Poznanski, Manali Mukherjee, Nan Zhao, Parameswaran Nair, Chynna Huang
Publikováno v:
Allergy. 76:375-379
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f84ebfb2468c975a0ca50a1c2d2e54c
https://doi.org/10.1111/all.14514
https://doi.org/10.1111/all.14514
Autor:
Jonathan L. Bramson, Marianne V. Chew, Jeremy A. Hirota, Niamh J. Cashell, Mira M. Shenouda, Ali A. Ashkar, Sophie M. Poznanski, Richard Hogg, Tyrah M. Ritchie, Quynh T. Cao, Joanne A. Hammill, Sukhbinder Dhesy-Thind, Eduardo A. Rojas, Ana L. Portillo
Publikováno v:
iScience, Vol 24, Iss 6, Pp 102619-(2021)
iScience
iScience
Summary Despite the remarkable success of chimeric antigen receptor (CAR)-T cells against hematologic malignancies, severe off-tumor effects have constrained their use against solid tumors. Recently, CAR-engineered natural killer (NK) cells have emer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dc2c60ee64fecd6302b4282435a8c17
http://www.sciencedirect.com/science/article/pii/S2589004221005873
http://www.sciencedirect.com/science/article/pii/S2589004221005873
Publikováno v:
Cells
Cells, Vol 10, Iss 708, p 708 (2021)
Cells, Vol 10, Iss 708, p 708 (2021)
As highlighted by the COVID-19 global pandemic, elderly individuals comprise the majority of cases of severe viral infection outcomes and death. A combined inability to control viral replication and exacerbated inflammatory immune activation in elder
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e96681a86a1f9a12541741788cc7a6f6
http://hdl.handle.net/11375/26583
http://hdl.handle.net/11375/26583
Autor:
Ronny Ben-Avi, Abdullah El-Sayes, Ali A. Ashkar, Ana L. Portillo, Marianne V. Chew, Yaron Shargall, Sophie M. Poznanski, Isabella Y. Fan, Eduardo A. Rojas, Tyrah M. Ritchie
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 1 (2021)
Journal for Immunotherapy of Cancer
Journal for Immunotherapy of Cancer
Lung cancer remains the leading cause of cancer death worldwide despite the significant progress made by immune checkpoint inhibitors, including programmed death receptor-1 (PD1)/PD ligand 1 (PDL1)-blockade therapy. PD1/PDL1−blockade has achieved u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5b1e6707a934c1eebd002288801dc46
https://jitc.bmj.com/content/9/1/e001933.full
https://jitc.bmj.com/content/9/1/e001933.full